Cystic pancreatic lesions - do we need radical surgery?

The results of 205 puncture biopsies of solid and cystic pancreatic lesions performed in 202 patients at the Republican Oncological Dispensary of the Republic of Karelia for a 7-year period (2009-2015) are presented. Informative material for morphological investigation was obtained in 95.5% of cases. A comparison of results of cytological examination of the material from 56 patients with pancreatic lesions with histological data was carried out. The efficiency of the cytological method was 90.6%, sensitivity - 87.8%, specificity - 100%. To determine histological form of tumor in cytological examination of the material of the pancreas was successful in 82.1% of cases.

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EFFICIENCY OF ADJUVANT XELOX CHEMOTHERAPY FOR PATIENTS WITH RESECTABLE GASTRIC IN RUSSIA (SINGLE INSTITUTION RETROSPECTIVE STUDY)

Problems in oncology ◽

10.37469/0507-3758-2019-65-2-256-262 ◽

2019 ◽

Vol 65 (2) ◽

pp. 256-262

Author(s):

Ivan Stilidi ◽

Sergey Nered ◽

Aleksey Kalinin ◽

Olesya Rossomakhina ◽

Anton Barchuk

Keyword(s):

Gastric Cancer ◽

Adjuvant Chemotherapy ◽

Radical Surgery ◽

Univariate Analysis ◽

European Population ◽

Single Institution ◽

Regional Lymph Nodes ◽

Lymph Nodes Metastasis ◽

Retrospective Assessment ◽

Resectable Gastric Cancer

Introduction. The effectiveness of the Asian regimen of adjuvant chemotherapy in patients with gastric cancer in the European population remains unclear. The aim of our study was a retrospective assessment of adjuvant chemotherapy (XELOX regimen) after radical surgery (R0) on overall survival. Methods. Database of pts with resectable gastric cancer with stage >pT3 and/or pN+ and M0, who were operated (R0) at single oncological institution during 2007-2017 was reviewed. In univariate and multivariate analyzes were included demographic characteristics, type of tumor according to Lauren, stage, type of treatment and others. Results. 396 pts were identified and 286 were available for analysis.106 (37%) pts received at least one cycle of adjuvant chemotherapy. In univariate analysis, 5OS rate was 64% [95% Cl, 52-80] и 56% [95% Cl, 48-64; p=0,21] in patients received adjuvant chemotherapy and only surgical treatment. After stratifying patients depending on the regional lymph nodes metastasis, 5OS rate in pts with pN1-3 was 69% [95% CI, 57-85] vs 47% [95% CI, 39-58; p = 0,01], respectively...

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Cosmetics or Radical Surgery? What's Right For the Top Levels of the U.S Defense Establishment as it Downsizes?

10.21236/ada264052 ◽

1993 ◽

Author(s):

Michal R. Robinson

Keyword(s):

Radical Surgery ◽

The U.S

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Radical Surgery for Carcinoma of the Middle Ear

Proceedings of the Royal Society of Medicine ◽

10.1177/003591577206500310 ◽

1972 ◽

Vol 65 (3) ◽

pp. 248-249

Author(s):

D C Bodenham

Keyword(s):

Middle Ear ◽

Radical Surgery

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T2 Gallbladder Cancer—Aggressive Therapy is Warranted

The American Surgeon ◽

10.1177/000313481608200612 ◽

2016 ◽

Vol 82 (6) ◽

pp. 518-521 ◽

Cited By ~ 2

Author(s):

Mohd Raashid Sheikh ◽

Houssam Osman ◽

Susannah Cheek ◽

Shenee Hunter ◽

Dhiresh Rohan Jeyarajah

Keyword(s):

Clinical Presentation ◽

Radical Surgery ◽

Radical Resection ◽

Gall Bladder Cancer ◽

Incidental Diagnosis ◽

Radical Cholecystectomy ◽

Node Positive ◽

Operative Findings ◽

Worse Prognosis

Treatment of gall bladder cancer (GBC) has traditionally been viewed with pessimism and lymph node positivity has been associated with worse prognosis. The aim of this study is to analyze the role of radical cholecystectomy in T2 tumors. All patients who underwent surgery for GBC between September 2005 and June 2014 were identified retrospectively. Data collected included clinical presentation, operative findings, and histopathological data. Twenty-five patients had incidental GBC diagnosis after cholecystectomy. Ten patients were T2 on initial cholecystectomy pathology and all underwent radical resection. Two patients were N1 on initial cholecystectomy pathology. Four were upstaged to N1 and two patients were upstaged to T3 after further surgery. Overall, 60 per cent patients with T2 disease had node positivity and 60 per cent were upstaged by further surgery. Eleven patients were diagnosed on imaging. Four of these patients were unresectable and six were either stage T3 or higher or node positive. Sixty per cent of T2 GBC was node positive and 60 per cent were upstaged with radical cholecystectomy. This finding supports the call for radical resection in patients with incidental diagnosis of T2 tumor on cholecystectomy. This study also emphasizes the role of radical surgery in accurate T staging.

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