Intercepting the Nazarov Oxyallyl Intermediate with α-Formylvinyl Anion Equivalents to Access Formal Morita–Baylis–Hillman Alkylation Products
Keyword(s):
A Lewis acid catalyzed cationic domino reaction involving sequential electrocyclization and polar addition of allenol ethers onto the resulting oxyallyl species is described. The overall sequence allows a highly stereoselective synthesis of densely substituted cyclopentanoid compounds containing α-formylvinyl functionality which is formally equivalent to products of a Morita–Baylis–Hillman alkylation process.
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2001 ◽
Vol 7
(3)
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pp. 565-572
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2006 ◽
Vol 348
(7-8)
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pp. 924-930
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2011 ◽
Vol 76
(4)
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pp. 1045-1053
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2020 ◽
Vol 2020
(44)
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pp. 6814-6814
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