Use of Porcine Small Intestinal Submucosal Grafts in Skull Base Reconstruction after Resection of Cerebellopontine Angle Tumors

2019 ◽  
Author(s):  
Douglas Totten ◽  
Robert Yawn ◽  
Nauman Manzoor ◽  
Matthew Dedmon ◽  
Reid Thompson ◽  
...  
2003 ◽  
Vol 50 (1) ◽  
pp. 63-67
Author(s):  
Vladimir Bascarevic ◽  
Miroslav Samardzic ◽  
Lukas Rasulic ◽  
Vesna Simic

The facial nerve is main motor nerve of the face and its injury leads to total ipsilateral paralysis. There are several surgical procedures in reconstruction of the facial nerve, and the most frequent one is hypoglosso-facial anastomosis. In this study were analysed a series of 69 patients operated on Institute of neurosurgery from 1981 to 2000 year. The most frequent cause of injury was the operation of cerebellopontine angle tumors, as well as the skull base fractures. Hypoglosso-facial anastomosis was done in 57 patients, in 5 cases we performed nerve grafting in the cerebellopontine angle, and in 7 patients the facial nerve was operated peripherally. Results were analyzed in 27 of 57 patients with hipoglosso-facial nerve anastomosis. Functional recovery was achived in 22 (81,4%) patients.


Author(s):  
Douglas J. Totten ◽  
Nauman F. Manzoor ◽  
Kristen L. Yancey ◽  
Robert J. Yawn ◽  
David S. Haynes ◽  
...  

Abstract Objective To compare the use of porcine small intestinal submucosal grafts (SISG) and standard autologous material (fascia) in prevention of cerebrospinal fluid (CSF) leak and pseudomeningocele formation after translabyrinthine resection. Setting Set at the tertiary skull base center. Methods This is a retrospective chart review. After Institutional Review Board approval, we performed a retrospective cohort study evaluating CSF leak in patients who underwent resection of lateral skull base defects with multilayered reconstruction using either fascia autograft or porcine SISGs. Demographics were summarized with descriptive statistics. Logistic regression was used to compare autograft and xenograft cohorts in terms of CSF complications. Results Seventy-seven patients underwent lateral skull base resection, followed by reconstruction of the posterior cranial fossa. Of these patients, 21 (27.3%) underwent multilayer repair using SISG xenograft. There were no significant differences in leak-associated complications between autograft and xenograft cohorts. Ventriculoperitoneal shunt was necessary in one (1.8%) autograft and one (4.8) xenograft cases (p = 0.49). Operative repair to revise surgical defect was necessary in three (5.4%) autograft cases and none in xenograft cases. Conclusion The use of SISG as a component of complex skull base reconstruction after translabyrinthine tumor resection may help reduce CSF leak rates and need for further intervention.


2013 ◽  
Vol 74 (S 01) ◽  
Author(s):  
Mihir Patel ◽  
Robert Taylor ◽  
Trevor Hackman ◽  
Deanna Sasaki-Adams ◽  
Matthew Ewend ◽  
...  

Author(s):  
Anat Wengier ◽  
Dan Fliss ◽  
Zvi Ram ◽  
Nevo Margalit ◽  
Avraham Abergel

Sign in / Sign up

Export Citation Format

Share Document