scholarly journals Local Drug Delivery in periodontal diseases. ……A Review

2016 ◽  
Vol 06 (01) ◽  
pp. 074-079
Author(s):  
Amitha Ramesh ◽  
Agumbe Priyanka Prakash ◽  
Biju Thomas

AbstractPeriodontitis is an immuno-inflammatory disease of the tissues surrounding the teeth. Various treatment modalities like mechanical debridement and use of antimicrobials have been followed in the treatment of such conditions. Introduction of local drug delivery system in the periodontal pocket is a promising therapeutic modality for achieving better clinical outcomes when used as an adjunct to conventional non surgical periodontal therapy. Intensive research efforts are now focussed on the development of new strategies for more effective treatment.

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 192-199
Author(s):  
Dhivyadharshini J ◽  
Ezhilarasan ◽  
Jayalakshmi Somasundaram

Oral diseases play a serious challenge to public health around the world. When left untreated, both the mouth and also the remaining the body would be adversely affected by oral diseases. Different treatment modalities are available for various dental diseases, but the most downside of those modern drug treatments are the frequent side effects related to their use. This has contributed to renewing interest in the development of novel plant-derived anti-infective natural compounds. Curcumin is an anti-inflammatory agent that occurs naturally, with different biological and medicinal properties. It has proven anti-inflammatory, antioxidant, antimicrobial, hepato-protective, immuno-stimulant, antiseptic, and anti-mutagenic properties. Due to these properties, it is especially useful in dentistry for the treatment of periodontal diseases and oral cancers. Turmeric can also be utilized in alternative treatments as a pit and fissure sealant, mouthwash and subgingival irrigant. Its gel form can even be used as a local drug delivery system. It is evaluated with a view to mitigate the human diseases, particularly in cancer and its potential to reduce cancer risk. Curcumin has only negligible side effects such as diarrhoea, diarrhoea, allergic skin reaction, gastric pain. The objective of this article is to review the efficacy and therapeutic properties of curcumin in maintaining oral health.


2015 ◽  
Vol 3 (24) ◽  
pp. 4871-4883 ◽  
Author(s):  
Yuqiong Wu ◽  
Lunguo Xia ◽  
Yuning Zhou ◽  
Wudi Ma ◽  
Na Zhang ◽  
...  

Icariin has been identified to promote osteogenic differentiation of bone mesenchymal stem cells (BMSCs).


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Evgenii Rubalskii ◽  
Stefan Ruemke ◽  
Christina Salmoukas ◽  
Andrey Aleshkin ◽  
Svetlana Bochkareva ◽  
...  

2020 ◽  
Vol 56 (64) ◽  
pp. 9190-9193
Author(s):  
Xin Shen ◽  
Zhenxia Zhou ◽  
Dongmei Qi ◽  
Yanchao Li ◽  
Zhiying Zeng ◽  
...  

Self-assembled highly uniform microspheres has been developed as a local drug delivery system for effective synergistic immunotherapy.


2008 ◽  
Vol 118 (4) ◽  
pp. 706-711 ◽  
Author(s):  
David P. Paulson ◽  
Waleed Abuzeid ◽  
Hao Jiang ◽  
Tomoyuki Oe ◽  
Bert W. O'Malley ◽  
...  

2008 ◽  
Vol 466 (6) ◽  
pp. 1377-1382 ◽  
Author(s):  
Scott P. Noel ◽  
Harry Courtney ◽  
Joel D. Bumgardner ◽  
Warren O. Haggard

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