scholarly journals The Effectiveness of 0.2% Chlorhexidine Gel on Early Wound Healing after Tooth Extraction: A Randomized Controlled Trial

Author(s):  
Amaliya Amaliya ◽  
Rika Ramadhanti ◽  
Indra Hadikrishna ◽  
Tantry Maulina

Abstract Objective This study aimed to evaluate the effect of 0.2% chlorhexidine (CHX) gel on wound healing after tooth extraction. Materials and Methods A single blind, randomized controlled trial was performed recruiting 32 participants who underwent dental extractions. Patients were randomly allocated for CHX group or placebo group. The primary outcomes were wound closure measured with calipers and healings were assessed by Landry et al index after 7 days of topical application of allocated gels on extraction sites. Results The wound closures were greater in CHX group compared with placebo group and healing scores were correlated with the use of CHX gel (p-value < 0.05). Conclusion In a population of healthy nonsmoker adults, application of 0.2% CHX gel twice a day for 7 days after tooth extraction has a beneficial effect on wound healing.

2020 ◽  
Vol 5 (1) ◽  
pp. 45
Author(s):  
Zaki Irwan ◽  
Andi Salim ◽  
Adriyani Adam

Handling of nutritional problems of children under five can be done through the development of food products in the form of Moringa leaf flour cookies and Moringa seed flour cookies given to toddlers, and then assessed an increase in body weight and nutritional status. The purpose of the study was to look at differences in body weight and nutritional status after intervention from Moringa leaf flour cookies and Moringa seed flour cookies in toddlers. The study design uses a Randomized Controlled Trial Single Blind Pre-post Study. The study was conducted in the working area of the Tampa Padang Public Health Center in August-October 2019 on children aged 3-5 years. The number of samples was 50 people, 25 children have interfered with Moringa leaf flour cookies, and 25 children were intervened by Moringa seed flour. Analysis of nutrient consumption of toddler foods using the Nutri Survey program. Maternal nutrition consumption is expressed in percent of RDA. Statistical analysis using the T-test. The results showed changes in body weight before and after giving Moringa seed cookies and Moringa leaf cookies (p=0,025). There is a difference in the increase in weight of the two groups of samples, but statistically has not been able to improve the nutritional status, both those who were given Moringa seed flour substitute cookies and those who were given Moringa leaf flour substitution cookies (p=0,495). In conclusion, there is a change in toddler's body weight, but it is not yet significant to the nutritional status of toddlers. Penanganan masalah gizi anak balita dapat dilakukan melalui pengembangan produk pangan berupa cookies tepung daun kelor dan cookies tepung biji kelor yang diberikan kepada balita, selanjutnya dinilai peningkatan Berat Badan dan Status gizinya. Tujuan penelitian yaitu melihat perbedaan berat badan dan status gizi setelah diintervensi cookies tepung daun kelor dan cookies tepung biji kelor pada anak balita. Desain penelitian menggunakan Randomized Controlled Trial Single Blind Pre-post Study. Penelitian dilakukan di Wilayah Kerja Puskesmas Tampa Padang Kecamatan Kaluku, Kabupaten Mamuju Sulawesi Barat. Waktu penelitian dimulai pada bulan Agustus – Oktober 2019 terhadap anak balita berumur 3-5 tahun. Jumlah sampel 50 orang, 25 anak diintervensi cookies tepung daun kelor dan 25 anak diintervensi tepung biji kelor. Analisis zat gizi konsumsi pangan anak balita menggunakan program Nutri Survei. Konsumsi gizi ibu dinyatakan dalam persen AKG. Analisis statistik menggunakan uji T. Hasil penelitian menunjukkan perubahan berat badan sebelum dan setelah pemberian cookies biji kelor dan cookies daun kelor dengan nilai p=0,025 (p-value<0,05). Terdapat perbedaan peningkatan BB kedua kelompok sampel, namun secara statistik belum bisa memperbaiki status gizi, baik yang diberi cookies subtitusi tepung biji kelor maupun yang diberi cookies subtitusi tepung daun kelor dengan nilai p=0,495 (p-value>0,05). Kesimpulan, terdapat perubahan berat badan balita namun belum signifikan terhadap status gizi balita  yang mendapatkan cookies berbahan daun kelor.


2021 ◽  
Vol 15 (8) ◽  
pp. 1852-1854
Author(s):  
Aneeque Alam Khan ◽  
Kiran Mehwish ◽  
Ravi Kumar ◽  
Pavan Kumar ◽  
Tahir Ali ◽  
...  

Aim: To compare the frequency of absence of pain with injection paracetamol versus placebo given before injection rocuronium in patients undergoing elective procedures Study design: Randomized Controlled Trial Place and duration of study: Dept of Anaesthesia, Civil Hospital, Karachi from 15th January to 14th July 2017. Methodology: One hundred and two patients aged 25-75 years of either gender undergoing elective surgery were enrolled. The lottery method was used to divide the patients into two equal groups. Paracetamol (5 mL, 10 mg/mL) or normal saline (5 mL) were used as pretreatment solutions. When the tourniquet was removed after 2 minutes, the rocuronium at 1% concentration was injected throughout the 10 second’s period. Patients were then advised and asked to rate their pain on the hand's dorsum using VAS. Results: Mean age of the patients was 44.11±7.75 years. Mean pain score was 1.49±1.38. Significant difference was observed in the mean pain score in between paracetamol and placebo group (p-value <0.001). Overall absence of pain was found in 49 (40.8%). Absence of pain was found to be higher 34 (69.4%) in paracetamol group as compared to placebo group (p-value <0.001). Conclusion: Frequency of absence of pain found lower in patients undergoing elective procedures with injection paracetamol versus placebo given before injection rocuronium. Keywords: Injection rocuronium, Elective procedures, Injection paracetamol, Absence of pain


2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Elexis C. Kierstead ◽  
Emily Harvey ◽  
Denisse Sanchez ◽  
Kimberly Horn ◽  
Lorien C. Abroms ◽  
...  

Abstract Objective Morbidity and mortality from smoking-related diseases among people living with HIV (PLWH) in the U.S. surpasses that due to HIV itself. Conventional smoking cessation treatments have not demonstrated strong efficacy among PLWH. We conducted a pilot randomized controlled trial (RCT) to evaluate a tailored smoking cessation intervention based on the minority stress model. We compared standard of care counseling (SOC) to a tailored intervention (TI) including one face-to-face counseling session incorporating cognitive behavioral therapy to build resilience, and 30 days of 2-way text messaging. Results The primary outcome was smoking cessation. Secondary outcomes included cigarettes per day (CPD), exhaled carbon monoxide (CO), and cessation self-efficacy. A total of 25 participants were enrolled (TI:11, SOC:14), and 2 were lost to follow-up. There were no significant differences in quit rates between study groups. However, there was a significantly greater decrease in CPD in the TI versus SOC (13.5 vs. 0.0, p-value:0.036). Additionally, self-efficacy increased in both groups (TI p-value:0.012, SOC p-value:0.049) and CO decreased in both groups (TI p-value: < 0.001, SOC p-value:0.049). This intervention shows promise to support smoking cessation among PLWH. A larger study is needed to fully evaluate the efficacy of this approach. Clinical trial: Trial Registration: Retrospectively registered (10/20/2020) NCT04594109.


2010 ◽  
Vol 38 (05) ◽  
pp. 849-859 ◽  
Author(s):  
Mei-Yuan Sun ◽  
Ching-Liang Hsieh ◽  
Yung-Yen Cheng ◽  
Hung-Chang Hung ◽  
Tsai-Chung Li ◽  
...  

Chronic neck myofascial pain syndrome (MPS) is a common disorder seen in clinics. There is no gold standard method to treat myofascial pain. We investigated the effects of acupuncture on patients with chronic neck MPS by a single-blind randomized controlled trial. A total of 35 patients were randomly allocated to an acupuncture group (AG) or a sham acupuncture group (SG). Each subject received acupuncture treatment twice per week for three consecutive weeks. The primary outcome measure was quality of life as assessed with Short Form-36, and secondary outcome measures were neck range of motion (ROM), motion-related pain, and Short-Form McGill Pain Questionnaire (SF-MPQ), as determined by a blinded investigator. The clinical assessments were made before treatment (BT) and after six acupuncture treatments (AT), as well as four weeks (F1) and 12 weeks (F2) after the end of the treatment. A total of 34 patients completed the trial. The results indicated that there is no significant difference in the ROM, motion-related pain, and SF-MPQ scores between AG and SG at AT, F1 and F2 (all p > 0.05). However, AG has greater improvement in physical functioning and role emotional of Short Form-36 quality of life at F2. The results indicate that acupuncture may be used to improve the quality of life in patients with chronic neck MPS.


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