scholarly journals Use of a Styrene-Maleic Anhydride Copolymer as an Adjuvant with Testosterone-Serum Albumin Immunogens and its Application to Increasing Ovulation Rate in the Ewe

1986 ◽  
Vol 39 (1) ◽  
pp. 99
Author(s):  
MSF Wong ◽  
RM Hoskinson ◽  
RI COX ◽  
D O Hawthorne ◽  
DH Solomon ◽  
...  

A synthetic poly(styrene-maleic anhydride) copolymer of average molecular weight 470000 potentiated a testosterone-binding antibody response during immunization of sheep with immunogenic testosterone- 3-carboxymethyloxime-serum albumin conjugates.

Polymers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 2243
Author(s):  
Jiali Qu ◽  
Yi Gao ◽  
Wantai Yang

In this paper, we developed a reactive molecular dynamics (RMD) scheme to simulate the Self-Stable Precipitation (SP) polymerization of 1-pentene and cyclopentene (C5) with maleic anhydride (MAn) in an all-atom resolution. We studied the chain propagation mechanism by tracking the changes in molecular conformation and analyzing end-to-end distance and radius of gyration. The results show that the main reason of chain termination in the reaction process was due to intramolecular cyclic entanglement, which made the active center wrapped in the center of the globular chain. After conducting the experiment in the same condition with the simulation, we found that the distribution trend and peak value of the molecular-weight-distribution curve in the simulation were consistent with experimental results. The simulated number average molecular weight (Mn) and weight average molecular weight (Mw) were in good agreement with the experiment. Moreover, the simulated molecular polydispersity index (PDI) for cyclopentene reaction with maleic anhydride was accurate, differing by 0.04 from the experimental value. These show that this model is suitable for C5–maleic anhydride self-stable precipitation polymerization and is expected to be used as a molecular weight prediction tool for other maleic anhydride self-stable precipitation polymerization system.


PEDIATRICS ◽  
1959 ◽  
Vol 24 (4) ◽  
pp. 521-522
Author(s):  
ROBERT A. ULSTROM

Loss of plasma protein into the gastrointestinal tract in the absence of actual bleeding has recently been demonstrated as a cause of "idiopathic hypoproteinemia." The euphonious name, "exudative enteropathy," has been used by Gordon to describe a group of nine patients, including a 2-year-old boy, whose common finding was hypoproteinemia due to loss of plasma protein into the gastrointestinal tract. A concomitant report by Schwartz and Jarnum confirms the association of these events in four additional patients. Although the first such patient reported had quantities of plasma protein present in the gastric juice sufficient to allow their demonstration by electrophoresis, the rapid digestion of the proteins by the enzymes normally present in the gastrointestinal tract has required the use of less direct methods in most of the subsequent cases. Using a preparation of I131-labelled polyvinyl pyrrolidone (a plasma substitute with average molecular weight the same as serum albumin) Gordon has devised a test that avoids the problems created by the gastrointestinal digestion of protein.


2009 ◽  
Vol 30 (3) ◽  
pp. 420-426 ◽  
Author(s):  
A. M. Al-Sabagh ◽  
M. R. Noor El-Din ◽  
R. E. Morsi ◽  
M. Z. Elsabee

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