Prevalence of cystic metastases in a consecutive cohort of surgically removed branchial cleft cysts

2021 ◽  
pp. 1-6
Author(s):  
Lalle Hammarstedt Nordenvall ◽  
Evelina Jörtsö ◽  
Mathias von Beckerath ◽  
Edneia Tani ◽  
Sushma Nordemar ◽  
...  
2003 ◽  
Vol 127 (4) ◽  
pp. e205-e208
Author(s):  
Elliot Carter ◽  
Ozlem Ulusarac

Abstract We report a case of multiple lymphoepithelial cysts of the thyroid gland in a patient with severe chronic lymphocytic thyroiditis. Lymphoepithelial cysts of the thyroid gland are rare lesions that are histologically similar to branchial cleft cysts found in the lateral neck. The cysts have an epithelial lining that is usually stratified squamous epithelium but may be focally respiratory-type epithelium. Abundant lymphoid tissue is present beneath the epithelium, and lymphoid follicles with reactive germinal centers are common features in the walls of the cysts. Because of their similarity to branchial cleft cysts and the presence of intrathyroidal branchiae-derived structures such as thymus and parathyroid gland tissue in the vicinity of some cysts, lymphoepithelial cysts of the thyroid have been postulated to arise from remnants of branchial derivatives; origination from solid cell nest remnants of the ultimobranchial bodies has been raised as a possibility. A definitive origin, however, has not been established. An association with chronic thyroiditis has been noted in 8 of the previously reported 16 cases occurring in a background of Hashimoto or chronic lymphocytic thyroiditis.


2021 ◽  
Vol 162 (15) ◽  
pp. 595-600
Author(s):  
Tamás Major ◽  
Krisztina Szarka ◽  
Zsófia Nagy ◽  
Ilona Kovács ◽  
Csaba Balog ◽  
...  

Összefoglaló. A lateralis cysticus nyaki terimék két leggyakoribb oka a branchiogen cysta és a cysticus nyaki áttét. Az átfedő lokalizáció (a leggyakrabban a IIA nyaki régióban), a betegek életkora és az esetenként hirtelen kezdet alapján a két leggyakoribb ok differenciáldiagnózisa nagy kihívást jelenthet. Egy hirtelen fellépő fájdalmas, bal oldali nyaki duzzanattal, dysphagiával és lázzal jelentkező 72 éves férfi esetét ismertetjük. A nyak komputertomográfiás vizsgálata egy 6 cm legnagyobb átmérőjű, vastag falú, többrekeszes cysticus terimét igazolt. Infektív branchiogen cysta lehetőségére gondolva az elváltozást eltávolítottuk. A szövettan azonban p16-pozitív laphámrákot igazolt. A primer tumort végül az ipsilateralis tonsilla palatina állományában sikerült azonosítani. A beteg definitív radioterápiában részesült, és 18 hónappal a diagnózis után tumormentes. A nyaki cystákon, az infektív nyaki cystákon és a cysticus metastasisokon kívül a humán papillómavírussal összefüggő szájgarati laphámrákok infektív cysticus vagy necroticus metastasisait is figyelembe kell venni a lateralis cysticus nyaki terimék differenciáldiagnózisában. Orv Hetil. 2020; 162(15): 595–600. Summary. Branchial cleft cysts and cystic neck metastases are the two most common causes of cystic lateral neck masses. Based on the overlapping location (neck level IIA), patient age at onset and the occasionally sudden onset, their differential diagnosis is challenging. We present a 72-year-old male presenting with a suddenly emerging painful, left-sided neck swelling, dysphagia and fever. Computed tomography showed a 6 cm thick-walled multicystic mass. With the suspected diagnosis of an infected branchial cleft cyst, the lesion was removed. Histology confirmed p16 positive squamous cell carcinoma. Primary tumor was identified in the ipsilateral palatine tonsil. Definive radiotherapy was performed and the patient is free of disease at the 18-month follow-up. Beyond pure and infected branchial cleft cysts and pure cystic metastases, infected cystic or necrotic metastasis of human papillomavirus associated oropharyngeal squamous cell carcinoma should be included in the differential diagnosis of cystic lateral neck lesions. Orv Hetil. 2021; 162(15): 595–600.


1998 ◽  
Vol 108 (10) ◽  
pp. 1524-1527 ◽  
Author(s):  
Jean-Yves Sichel ◽  
Doron Halperin ◽  
Itzhak Dano ◽  
Eric Dangoor

2005 ◽  
Vol 21 (2) ◽  
pp. 137-141 ◽  
Author(s):  
Anne Walton ◽  
Kim Michael

2009 ◽  
Vol 13 (2) ◽  
pp. 79-85 ◽  
Author(s):  
Nikolaos Papadogeorgakis ◽  
Vassilis Petsinis ◽  
Eleni Parara ◽  
Konstantinos Papaspyrou ◽  
Lampros Goutzanis ◽  
...  

1994 ◽  
Vol 33 (1) ◽  
pp. 72-74 ◽  
Author(s):  
William M. Baader ◽  
James M. Lewis

Head & Neck ◽  
2009 ◽  
Vol 31 (5) ◽  
pp. 695-698 ◽  
Author(s):  
Wei-Liang Chen ◽  
Si-Lian Fang

2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
Jan D. Raguse ◽  
Ioannis Anagnostopoulos ◽  
Christian Doll ◽  
Max Heiland ◽  
Korinna Jöhrens

Background. Even though branchial cleft cysts are currently accepted as a congenital anomaly, there is often a long delay until clinical presentation; branchial cleft cysts classically appear in the second to fourth decade of life. Our observation of their occurrence in three pregnant women encouraged us to contemplate a possible hormonal influence. Methods. Immunohistological analysis was performed for the evaluation of the estrogen receptor alpha (ERα) in paraffin-embedded tissue specimens of 16 patients with a diagnosis of branchial cleft cyst, with three of them being pregnant. Results. Expression of ERα was detected within epithelial cells only in branchial cleft cysts in pregnant females; moreover, higher growth fractions (Ki-67/Mib1) were found. Conclusion. The fact that the estrogen receptor was expressed only in pregnant women, in contrast to 13 investigated cases, may suggest that the high level of estrogen in pregnancy is a possible explanation for the spontaneous growth of branchial cleft cysts.


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