Identifying chronic disease patients using predictive algorithms in pharmacy administrative claims: an application in rheumatoid arthritis

BackgroundRecently, the local governments in Japan implemented the measures for people requiring assistance during a disaster (PRAD). These measures aim to provide public assistance during a disaster for the citizens who registered themselves to the PRAD list in advance, by sharing their personal information among relevant local authorities. However, the needs for such assistance were not clear among chronic disease patients, and there are some concerns about privacy protection in relation to the PRAD list.ObjectivesThe objective of this study is to describe the attitudes toward the registration to the PRAD list among rheumatoid arthritis (RA) patients.MethodsStudy subjects were the members of a nationwide RA patient group in Japan. Of about 20,000 members, 1,477 who lived in the municipalities affected by disasters from 2004 to 2006 were enrolled. Self-administered questionnaires were sent by mail. The subjects were asked their attitudes toward the registration to the PRAD list and categorized into three groups: (1) no need for assistance; (2) need assistance but will not register; and (3) need assistance and wish to register or already registered. Their concerns about privacy protection as well as socio-demographic and health status were also asked.ResultsOf 1,477, 664 (45%) responded validly, and 596 (40%) answered on their attitudes toward the PRAD list. Of these, 365 (61%) reported they need assistance, though 30% of them (108) did not wish to register. A majority of the subjects concerned about privacy protection among those did not wish to register (65%) as well as among those wished to register (55%). Patients who lived alone, and those with low income were more likely to wish to register.ConclusionsThere are substantial needs for public assistance during a disaster among RA patients although the privacy protection issue would be a barrier to be overcome for successful utilization of the list.

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Medication adherence using self-report measures among chronic disease patients: A review

International Journal of Pharmaceutical Research ◽

10.31838/ijpr/2020.12.01.066 ◽

2020 ◽

Vol 12 (01) ◽

Keyword(s):

Chronic Disease ◽

Medication Adherence ◽

Self Report ◽

Chronic Disease Patients

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Role of Cytokines in the Pathogenesis of Anemia of Chronic Disease in Rheumatoid Arthritis

Clinical Immunology ◽

10.1006/clim.1999.4736 ◽

1999 ◽

Vol 92 (2) ◽

pp. 153-160 ◽

Cited By ~ 62

Author(s):

P.V. Voulgari ◽

G. Kolios ◽

G.K. Papadopoulos ◽

A. Katsaraki ◽

K. Seferiadis ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Chronic Disease ◽

Anemia Of Chronic Disease

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Rheumatoid arthritis: still a chronic disease

The Lancet ◽

10.1016/s0140-6736(12)62192-8 ◽

2013 ◽

Vol 381 (9870) ◽

pp. 884-886 ◽

Cited By ~ 22

Author(s):

Pierre Miossec

Keyword(s):

Rheumatoid Arthritis ◽

Chronic Disease

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Role of Biological Response Modifiers in the Treatment of Rheumatoid Arthritis - A Review

TAJ Journal of Teachers Association ◽

10.3329/taj.v18i1.3309 ◽

1970 ◽

Vol 18 (1) ◽

pp. 60-65

Author(s):

Md Azizul Haque ◽

ARM Saifuddin Ekram ◽

Quazi Tarikul Islam

Keyword(s):

Rheumatoid Arthritis ◽

Monoclonal Antibody ◽

Chronic Disease ◽

Receptor Antagonist ◽

Disease Progression ◽

Joint Damage ◽

Biological Response ◽

The Past ◽

Conventional Dmards

Rheumatoid arthritis is a chronic disease with the potential to cause substantial joint damage and disability. During the past 10 years, improved understanding of the pathophysiology of rheumatoid arthritis has led to several key changes in the approach to therapy. Most important of that is the development of some biological agents interfering with the activity of several important cytokines. Infliximab, etanarcept, and adalimumab are TNF blockers, anakinra is IL-1 receptor antagonist, and rituximab is anti CD-20 monoclonal antibody. These newer agents proved to be useful for alleviating symptoms and slowing the disease progression in the patients with RA who have failed to respond to conventional DMARDs. doi: 10.3329/taj.v18i1.3309 TAJ 2005; 18(1): 60-65

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Hospital-based chronic disease care model: protocol for an effectiveness and implementation evaluation

BMJ Open ◽

10.1136/bmjopen-2020-037843 ◽

2020 ◽

Vol 10 (7) ◽

pp. e037843

Author(s):

Jennifer Sumner ◽

Jason Phua ◽

Yee Wei Lim

Keyword(s):

Primary Care ◽

Chronic Disease ◽

Emergency Room ◽

Clinical Outcomes ◽

Qualitative Data ◽

Emergency Room Visit ◽

Type I ◽

Care Model ◽

Implementation Evaluation ◽

Chronic Disease Patients

IntroductionNovel and efficient healthcare approaches are needed to better serve increasingly older chronic disease patients. Many effective integrated chronic disease management strategies have emerged from the primary care sector. However, in many Asian and developing countries, primary care is underdeveloped, and patients prefer secondary-based services. The Integrated Generalist-led Hospital (IGH) care model is a new approach, which may be better suited for chronic disease patients in the local context.Methods and analysisA hybrid type I study on the effectiveness and implementation of the IGH care model will be conducted. Implementation evaluation will be informed by the Consolidated Framework of Implementation Research (CFIR). Quantitative and qualitative data will be collected through in-depth interviews and focus group discussions with staff, a staff survey, patient interviews, clinical outcomes and cost data. Clinical outcomes include the length of stay, readmission, emergency room visit rate and mortality. Clinical outcomes will be summarised and compared with a propensity-matched ‘usual care’ group (derived from the general medicine ward(s) at a separate hospital). The Kaplan-Meier approach will be used to estimate time until death and time until first readmission (both within 30 days of discharge) and time until discharge. Multivariate regression models will be used to investigate the association between the care model and occurrence of readmission, emergency room visit and death, all within 30 days of discharge. Qualitative data will be analysed using a thematic analysis method. Qualitative and quantitative data will also be coded according to the five domains of the CFIR.Ethics and disseminationThis protocol was reviewed and approved by the National Healthcare Group Domain Specific Review Board (NHG DSRB 2019/00308). Results will be published in peer-reviewed scientific journals and conference presentations. Findings will also be discussed with key stakeholders through local dissemination events.

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High Sedentary Behaviour and Low Physical Activity are Associated with Anxiety and Depression in Myanmar and Vietnam

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph16071251 ◽

2019 ◽

Vol 16 (7) ◽

pp. 1251 ◽

Cited By ~ 6

Author(s):

Supa Pengpid ◽

Karl Peltzer

Keyword(s):

Physical Activity ◽

Chronic Disease ◽

Sedentary Behaviour ◽

Sedentary Time ◽

Anxiety And Depression ◽

Cross Sectional ◽

High Physical Activity ◽

Chronic Disease Patients ◽

General Physical ◽

Activity Questionnaire

The study aimed to estimate independent and combined associations of sedentary behaviour and physical activity with anxiety and depression among chronic disease patients in Myanmar and Vietnam. The cross-sectional sample included 3201 chronic disease patients (median age 51 years, interquartile range 25) systematically recruited from primary care facilities in 2015. Sedentary time and physical activity were assessed with the General Physical Activity Questionnaire (GPAQ). Overall, the prevalence of sedentary time per day was 51.3% < 4 h, 31.2% between 4 and 8 h, and 17.5% 8 or more hours a day), and 30.7% engaged in low physical activity, 50.0% moderate, and 23.6% high physical activity. The prevalence of anxiety and depression was 12.7% and 19.9%, respectively. In the final logistic regression model, adjusted for relevant confounders, higher sedentary time (≥8 h) did not increase the odds for anxiety or depression, but moderate to high physical activity decreased the odds for anxiety and depression. Combined regression analysis found that participants with both less than eight hours of sedentary time and moderate or high physical activity had significantly lower odds of having anxiety and depression. Findings suggest an independent and combined association between moderate or high physical activity and low sedentary time with anxiety and/or depression among chronic disease patients in Myanmar and Vietnam.

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