Differential Predictors of Suicidal Ideation and Suicide Attempts: Internalizing Disorders and Substance Use in a Clinical Sample of Adolescents

2022 ◽  
pp. 1-11
Author(s):  
Lauren M. Berny ◽  
Emily E. Tanner-Smith
Keyword(s):  
Substance Use ◽  
Suicidal Ideation ◽  
Suicide Attempts ◽  
Clinical Sample ◽  
Internalizing Disorders

scholarly journals Associations between Abortion, Mental Disorders, and Suicidal Behaviour in a Nationally Representative Sample

2010 ◽  
Vol 55 (4) ◽  
pp. 239-247 ◽  
Author(s):  
Natalie P Mota ◽  
Margaret Burnett ◽  
Jitender Sareen
Keyword(s):  
Substance Use ◽  
Suicidal Ideation ◽  
Mental Disorders ◽  
Mental Disorder ◽  
Representative Sample ◽  
Suicide Attempts ◽  
World Health ◽  
Population Attributable Fractions ◽  
Attributable Fractions ◽  
Nationally Representative

Objective: Most previous studies that have investigated the relation between abortion and mental illness have presented mixed findings. We examined the relation between abortion, mental disorders, and suicidality using a US nationally representative sample. Methods: Data came from the National Comorbidity Survey Replication ( n = 3310 women, aged 18 years and older). The World Health Organization-Composite International Diagnostic Interview was used to assess mental disorders based on the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria and lifetime abortion in women. Multiple logistic regression analyses were employed to examine associations between abortion and lifetime mood, anxiety, substance use, eating, and disruptive behaviour disorders, as well as suicidal ideation and suicide attempts. We calculated the percentage of respondents whose mental disorder came after the first abortion. The role of violence was also explored. Population attributable fractions were calculated for significant associations between abortion and mental disorders. Results: After adjusting for sociodemographics, abortion was associated with an increased likelihood of several mental disorders—mood disorders (adjusted odds ratio [AOR] ranging from 1.75 to 1.91), anxiety disorders (AOR ranging from 1.87 to 1.91), substance use disorders (AOR ranging from 3.14 to 4.99), as well as suicidal ideation and suicide attempts (AOR ranging from 1.97 to 2.18). Adjusting for violence weakened some of these associations. Forall disorders examined, less than one-half of women reported that their mental disorder had begun after the first abortion. Population attributable fractions ranged from 5.8% (suicidal ideation) to 24.7% (drug abuse). Conclusions: Our study confirms a strong association between abortion and mental disorders. Possible mechanisms of this relation are discussed.

Suicidal Ideation and Suicide Attempts among Women Seeking Treatment for Substance Use and Trauma Symptoms

2018 ◽  
Vol 43 (2) ◽  
pp. 76-83 ◽  
Author(s):  
Stella M Resko ◽  
Sarah Kruman Mountain ◽  
Suzanne Browne ◽  
David C Kondrat ◽  
Michael Kral
Keyword(s):  
Substance Use ◽  
Suicidal Ideation ◽  
Suicide Attempts ◽  
Trauma Symptoms

scholarly journals Emergency Psychiatric Consultations During and After the COVID-19 Lockdown in Italy. A Multicentre Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Matteo Balestrieri ◽  
Paola Rucci ◽  
Davide Amendola ◽  
Miki Bonizzoni ◽  
Giancarlo Cerveri ◽  
...  
Keyword(s):  
Substance Use ◽  
Suicidal Ideation ◽  
Multicentre Study ◽  
Suicide Attempts ◽  
Gradual Increase ◽  
Psychiatric Services ◽  
Lower Percentage ◽  
Hospital Emergency ◽  
Psychiatric Hospitalizations ◽  
Hospital Emergency Departments

Aims: The aim was to analyse the psychiatric consultations in nine Italian hospital emergency departments, by comparing the lockdown and post-lockdown periods of 2020 with the equivalent periods of 2019.Methods: Characteristics of psychiatric consultations, patients, and drug prescriptions were analyzed. Joinpoint models were used to identify changes in the weekly trend of consultations.Results: A 37.5% decrease in the number of consultations was seen during the lockdown period and 17.9% after the lockdown. The number of individual patients seen decreased by 34.9% during the lockdown and 11.2% after the lockdown. A significant change in the number of consultations from week 11 to week 18 occurred, followed by a gradual increase. There was a higher percentage of patients with previous psychiatric hospitalizations during the lockdown period (61.1 vs. 56.3%) and a lower percentage after the lockdown (59.7 vs. 64.7%). During the lockdown there was a large increase in psychiatric consultations for substance use disorders, whereas more consultations for manic episodes occurred after the lockdown. A 3.4% decrease was observed in consultations for suicidal ideation and planning during the lockdown, followed by an upward rebound after the lockdown, along with an increase in consultations for suicide attempts. During lockdown antipsychotic and benzodiazepine prescriptions increased by 5.2 and 4.1%, respectively. After the lockdown, the number of compulsory hospitalizations was higher than in 2019.Conclusions: We observed a decrease of psychiatric consultations during and after the lockdown. There was an increase in consultations for manic episodes and suicidality after the lockdown. The focus of psychiatric services must remain high particularly in this latter period.

scholarly journals Associations of Substance Use Behaviors With Suicidal Ideation and Suicide Attempts Among US and Chinese Adolescents

2021 ◽  
Vol 11 ◽  
Author(s):  
Lan Guo ◽  
Wanxin Wang ◽  
Xueying Du ◽  
Yangfeng Guo ◽  
Wenyan Li ◽  
...  
Keyword(s):  
Substance Use ◽  
Suicidal Ideation ◽  
Alcohol Use ◽  
Suicide Attempts ◽  
Chinese Adolescents ◽  
Health Policies ◽  
Adolescent Group ◽  
Public Health Policies ◽  
The Us ◽  
Adolescent Groups

Background: Adolescence has been described as a period of increased health risk-taking behaviors. Given the variety of cultural contexts, healthcare systems, and public health policies in different regions, the present study aimed to determine whether there are similar or different associations of substance use behaviors with suicidal ideation and suicide attempts among US and Chinese adolescents.Methods: This study included a total of 14,765 US adolescents from the 2017 National Youth Risk Behavior Surveillance System (YRBSS) and 24,345 Chinese adolescents from the 2017 School-based Chinese Adolescents Health Survey (SCAHS).Results: The proportions of suicidal ideation and suicide attempts were 17.4 and 5.7% among US adolescents, which were higher than those among Chinese adolescents (suicidal ideation: 13.7% and suicide attempts: 2.7%). Among Chinese adolescents, the most common substance use behavior was “alcohol use (55.4%),” followed by “cigarette use (11.6%).” Among US adolescents, the most popular substance was alcohol (ever used: 55.9%), followed by marijuana (ever used: 34.6%). Moreover, alcohol use was significantly related to suicidal ideation/suicide attempts only in Chinese adolescents [suicidal ideation: Adjusted odds ratio (AOR) = 1.88, 95% CI = 1.71~2.06; suicide attempts: AOR = 2.12, 95% CI = 1.71~2.63], and marijuana use was associated with suicidal ideation and suicide attempts only in the US adolescent group (suicidal ideation: AOR = 1.23, 95% CI = 1.06~1.44; suicide attempts: AOR = 1.51, 95% CI = 1.21~1.87). Moreover, although the associations of prescription pain medication use with suicide attempts were significant in both Chinese and US adolescent groups, the adjusted associations were stronger in Chinese adolescents than in US adolescents (Chinese adolescents: AOR = 3.97, 95% CI = 2.76~5.72; US adolescents: AOR = 1.76, 95% CI = 1.43~2.16; P < 0.05).Conclusions: The associations of alcohol use with suicidal ideation and suicide attempts were only significant in Chinese adolescents. Marijuana use was associated with suicidal ideation and suicide attempts only in the US adolescent group. Although the associations of prescription pain medication use with suicide attempts were significant in both Chinese and US adolescent groups, the adjusted associations were significantly stronger for Chinese adolescents. These findings might be related to the differences in cultural contexts, healthcare systems, and public health policies in the two different countries.

scholarly journals Reciprocal relationships between substance use and disorders and suicidal ideation and suicide attempts in the Collaborative Study of the Genetics of Alcoholism

2017 ◽  
Vol 213 ◽  
pp. 96-104 ◽  
Author(s):  
Arpana Agrawal ◽  
Rebecca Tillman ◽  
Richard A. Grucza ◽  
Elliot C. Nelson ◽  
Vivia V. McCutcheon ◽  
...  
Keyword(s):  
Substance Use ◽  
Suicidal Ideation ◽  
Suicide Attempts ◽  
Collaborative Study ◽  
Reciprocal Relationships

Factors associated with lifetime suicidal ideation and suicide attempts in outpatients with substance use disorders

2018 ◽  
Vol 262 ◽  
pp. 440-445 ◽  
Author(s):  
Laia Rodríguez-Cintas ◽  
Constanza Daigre ◽  
María Dolores Braquehais ◽  
Raúl Felipe Palma-Alvarez ◽  
Lara Grau-López ◽  
...  
Keyword(s):  
Substance Use ◽  
Suicidal Ideation ◽  
Substance Use Disorders ◽  
Suicide Attempts ◽  
Factors Associated

scholarly journals Clustering suicidal phenotypes and genetic associations with brain-derived neurotrophic factor in patients with substance use disorders

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Romain Icick ◽  
Vanessa Bloch ◽  
Nathalie Prince ◽  
Emily Karsinti ◽  
Jean-Pierre Lépine ◽  
...  
Keyword(s):  
Substance Use ◽  
Substance Use Disorders ◽  
Neurotrophic Factor ◽  
Associated Factors ◽  
Suicide Attempts ◽  
Clinical Sample ◽  
Brain Derived Neurotrophic Factor ◽  
Structured Interview ◽  
Phenotypic Characterization ◽  
Multinomial Regression

AbstractSuicide attempts (SA), especially recurrent SA or serious SA, are common in substance use disorders (SUD). However, the genetic component of SA in SUD samples remains unclear. Brain-derived neurotrophic factor (BDNF) alleles and levels have been repeatedly involved in stress-related psychopathology. This investigation uses a within-cases study of BDNF and associated factors in three suicidal phenotypes (‘any’, ‘recurrent’, and ‘serious’) of outpatients seeking treatment for opiate and/or cocaine use disorder. Phenotypic characterization was ascertained using a semi-structured interview. After thorough quality control, 98 SNPs of BDNF and associated factors (the BDNF pathway) were extracted from whole-genome data, leaving 411 patients of Caucasian ancestry, who had reliable data regarding their SA history. Binary and multinomial regression with the three suicidal phenotypes were further performed to adjust for possible confounders, along with hierarchical clustering and compared to controls (N = 2504). Bayesian analyses were conducted to detect pleiotropy across the suicidal phenotypes. Among 154 (37%) ever suicide attempters, 104 (68%) reported at least one serious SA and 96 (57%) two SA or more. The median number of non-tobacco SUDs was three. The BDNF gene remained associated with lifetime SA in SNP-based (rs7934165, rs10835210) and gene-based tests within the clinical sample. rs10835210 clustered with serious SA. Bayesian analysis identified genetic correlation between ‘any’ and ‘serious’ SA regarding rs7934165. Despite limitations, ‘serious’ SA was shown to share both clinical and genetic risk factors of SA—not otherwise specified, suggesting a shared BDNF-related pathophysiology of SA in this population with multiple SUDs.

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