The mediation role of schizotypal traits in the relationship between childhood trauma and earlier onset of panic disorder

Psychosis ◽  
2021 ◽  
pp. 1-11
Author(s):  
Cansu Baygin ◽  
Levent Sevincok ◽  
Bilge Dogan ◽  
Doga Sevincok ◽  
Yasan Bilge Sair
1998 ◽  
Vol 43 (2) ◽  
pp. 148-153 ◽  
Author(s):  
Joel Paris

Objective: To examine the relationship between trauma in childhood and personality disorders in adulthood. Method: A review of the literature was conducted. Results: The reported associations between trauma and personality pathology are illuminated by the following research findings: 1) personality is heritable; 2) only a minority of patients with severe personality disorders report childhood trauma; and 3) children are generally resilient, and traumatic experiences do not consistently lead to psychopathology. Conclusions: The role of trauma in the personality disorders is best understood in the context of gene–environment interactions.


1998 ◽  
Vol 172 (6) ◽  
pp. 465-471 ◽  
Author(s):  
C. J. Bell ◽  
D. J. Nutt

BackgroundTricyclic (TCA) and monoamine oxidase inhibitor (MAOI) antidepressants are effective in the treatment of panic disorder. Two selective serotonin reuptake inhibitors (SSRIs) have also been licensed in the UK for this indication and studies with three other SSRIs have recently been completed. These provide further evidence for the role of serotonin in panic.MethodReview of clinical, animal and laboratory studies.ResultsSSRIs have been shown to be effective in the treatment of panic disorder. The reported rates of improvement of 60–70% of patients taking SSRIs are similar to those seen withTCAs and greater than placebo. Other serotonergic agents do not appear to be effective. Animal work and human studies including measures of 5-HT in plasma, cerebrospinal fluid and platelets, challenge paradigms and tryptophan depletion show that the relationship between 5-HT and anxiety is complex.ConclusionClinical trials have shown that of all the serotonergic agents only the SSRIs are effective in panic disorder. They are as beneficial as the TCAs and seem to be better tolerated which may be particularly significant in view of the chronic nature of the condition. Serotonin plays a role in panic disorder and serotonergic dysfunction, however the results and evidence do not fit one theory alone. It is also likely that different brain regions and 5-HTreceptors are involved in specific ways.


Appetite ◽  
2015 ◽  
Vol 91 ◽  
pp. 129-136 ◽  
Author(s):  
Vasiliki Michopoulos ◽  
Abigail Powers ◽  
Carla Moore ◽  
Stephanie Villarreal ◽  
Kerry J. Ressler ◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Pelin Karaca Dinç ◽  
Seda Oktay ◽  
Ayşegül Durak Batıgün

Abstract Background There is overwhelming evidence for a strong association between childhood trauma and adult psychopathology. This study aimed to investigate the mediation roles of alexithymia, sensory processing sensitivity, and emotional-mental processes in the relationship between childhood traumas and adult psychopathology. Methods The sample consisted of 337 people (78.9% female, 21.1% male) aged between 20 and 64 years. Participants filled the scales online via a Google form. Reading Mind in the Eyes (EYES), Sensory Processing Sensitivity Scale (SPS), Toronto Alexithymia Scale (TAS-26), Childhood Trauma Questionnaire (CTQ), and the Brief Symptom Inventory (BSI) were used. PROCESS (Model 4) macro was used to examine the mediating role of sensory processing sensitivity, alexithymia, and the EYES test results in the relationship between childhood trauma and psychopathology. Results The results of mediation analysis demonstrated that sensory processing sensitivity and alexithymia mediated the relationship between childhood trauma and adult psychopathology. However, the EYES test (mentalization) did not mediate in this relationship. Conclusion This study shows that childhood traumas may relate to more psychological symptoms in individuals with high sensory processing sensitivity and alexithymia. Our study may contribute to the understanding of what may lead to a person’s vulnerability to experiencing psychological symptoms after childhood trauma. It may be crucial that future treatment and intervention programs should include sensory sensitivity and alexithymia. Sensory processing sensitivity and alexithymia can be examined in the treatment of psychological problems of individuals who have experienced childhood trauma.


2021 ◽  
Author(s):  
Pelin KARACA DİNÇ ◽  
Seda OKTAY ◽  
Ayşegül DURAK BATIGÜN

Abstract Background There is overwhelming evidence for a strong association between childhood trauma and adult psychopathology. This study aims to investigate the mediation roles of alexithymia, sensory processing sensitivity, and emotional-mental processes in the relationship between childhood traumas and adult psychopathology. Methods 337 people (78.9% female, 21.1% male) between the ages of 20–64 participated in this study. Participants filled the scales online via google form. Reading Mind in the Eyes (EYES), Sensory Processing Sensitivity Scale (SPS), Toronto Alexithymia Scale (TAS-26), Childhood Trauma Questionnaire (CTQ), and the Brief Symptom Inventory (BSI) were used. SPSS Process (Model 4) was used to examine the mediating role of sensory processing sensitivity, alexithymia and the eyes test results in the relationship between childhood trauma and psychopathology. Results Sensory processing sensitivity and alexithymia have been found to mediate the relationship between childhood trauma and adult psychopathology. The eyes test (mentalization) was not found to have a mediating effect on this relationship. Conclusion This study shows that childhood traumas may relate more psychopathology in individuals with high sensory processing sensitivity and alexithymia. Our study may contribute to the understanding of what may lead to a person's vulnerability to experiencing psychopathology after childhood trauma. It may be important that future treatment and intervention programs should include sensory sensitivity and alexithymia. Sensory processing sensitivity and alexithymic characteristics of individuals can be examined in the treatment of psychological problems of individuals who have experienced childhood trauma.


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