Antiretroviral Therapy and Sexual Behavior: A Comparative Study between Antiretroviral- Naive and -Experienced Patients at an Urban HIV/AIDS Care and Research Center in Kampala, Uganda

Purpose: This study aimed to determine the quality of life among people living with HIV/AIDS based on the criteria for diagnosis and other factors.Methods: This study was conducted in the VCT clinic hospital of Dr. Moewardi. The population was HIV-positive patients with antiretroviral therapy. Data collection conducted through medical records and interview to patients. Results: Out of a total of 89 respondents, 66.29% were males and 71.91% were aged between 26-45 years. We found significant correlations for diagnosis of HIV/AIDS, opportunistic infections, time since HIV diagnosis, duration of ARV therapy, social support, modes of transport, sex, age, and marital status with the quality of life. Multivariate analysis obtained by each variable showed the strongest association with the quality of life was time since diagnosis, social support and duration of ARV therapy. Conclusion: The quality of life was better for those who have been diagnosed with HIV/AIDS ≥ 32 months, with social support, and who have been undergoing antiretroviral therapy ≥ 29 months. Improved counseling in the early days of ARV therapy is necessary to always maintain the treatment and provide support for their social life.

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Predictors of glucose metabolism and blood pressure among Ethiopian individuals with HIV/AIDS after one‐year antiretroviral therapy

Tropical Medicine & International Health ◽

10.1111/tmi.13544 ◽

2021 ◽

Author(s):

Hiwot Amare ◽

Mette F. Olsen ◽

Henrik Friis ◽

Åse B. Andersen ◽

Alemseged Abdissa ◽

...

Keyword(s):

Blood Pressure ◽

Antiretroviral Therapy ◽

Glucose Metabolism ◽

One Year ◽

Hiv Aids

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Assessing antiretroviral therapy success in HIV/AIDS morbidity and mortality trends in Brazil, 1990–2017: an interrupted time series study

International Journal of STD & AIDS ◽

10.1177/0956462420952989 ◽

2020 ◽

pp. 095646242095298

Author(s):

Augusto Cesar Lara de Sousa ◽

Tatiana de Araujo Eleuterio ◽

José Victor Afonso Coutinho ◽

Raphael Mendonça Guimarães

Keyword(s):

Time Series ◽

Antiretroviral Therapy ◽

Burden Of Disease ◽

Interrupted Time Series ◽

People Living With Hiv ◽

Disability Adjusted Life Years ◽

Disability Adjusted Life ◽

Life Years ◽

The Impact ◽

Hiv Aids

To describe the trends of HIV/AIDS metrics related to the burden of disease for Brazil between 1990 and 2017 we conducted a timeseries analysis for HIV/AIDS indicators by extracting data from the Global Burden of Disease study. We calculated traditional prevalence, incidence and mortality rates, the number of years lost by HIV-related deaths (YLL) and disability (YLD), and disability-adjusted life years (DALY). We estimated time series models and assessed the impact of highly active antiretroviral therapy (HAART) on the same indicators. In the set of disability-adjusted life years (DALY), the highest weight of its magnitude was due to YLL. There was a decline, especially after 1996, of DALY, mortality and YLL for HIV/AIDS. However, YLD, incidence, and prevalence increased over the same period. Also, the analysis of interrupted time series showed that the introduction of HAART into health policy had a significant impact on indicators, especially for DALY and YLL. We need to assess the quality of life of people living with HIV, especially among older adults. In addition, we need to focus on primary prevention, emphasizing methods to avoid infection and public policies should reflect this.

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Correlation between metabolic syndrome and relative telomere length shortening in HIV/AIDS patients on combined antiretroviral therapy

Experimental Gerontology ◽

10.1016/j.exger.2021.111269 ◽

2021 ◽

Vol 147 ◽

pp. 111269

Author(s):

Gordana Dragović ◽

Mladen Andjić ◽

Boško Toljić ◽

Djordje Jevtović ◽

Relja Lukić ◽

...

Keyword(s):

Metabolic Syndrome ◽

Antiretroviral Therapy ◽

Telomere Length ◽

Aids Patients ◽

Relative Telomere Length ◽

Combined Antiretroviral Therapy ◽

Hiv Aids

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Male circumcision and global HIV/AIDS epidemic challenges

African Journal of Urology ◽

10.1186/s12301-019-0005-2 ◽

2019 ◽

Vol 25 (1) ◽

Cited By ~ 2

Author(s):

Emiola Oluwabunmi Olapade-Olaopa ◽

Mudasiru Adebayo Salami ◽

Taiwo Akeem Lawal

Keyword(s):

Sexual Behavior ◽

Male Circumcision ◽

Preventive Measure ◽

Population Level ◽

Surgical Removal ◽

Main Body ◽

Prevention Measures ◽

Mortality And Morbidity ◽

Aids Epidemic ◽

Hiv Aids

Abstract Background Given the devastating mortality and morbidity associated with HIV/AIDS, many potential prevention measures against HIV infection continue to be explored. Most prevention methods are in the realm of sexual behavior change. However, of all aspects of human behavior, it is sexual behavior that is least amenable to change. Newer and simpler interventions are therefore required. Male circumcision, the surgical removal of some or all of the foreskin (or prepuce) from the penis, is one of the ways being promoted as a preventive measure. This paper reviews the scientific basis and evidence for the efficacy of male circumcision within the context of the global challenges involved. Main body We reviewed articles with emphasis on male circumcision and HIV/AIDS transmission. Published abstracts of presentations at international scientific meetings were also reviewed. Conclusions Current epidemiological evidence supports the promotion of male circumcision for HIV prevention, especially in populations with high HIV prevalence and low circumcision rates. Three notable randomized control trials strengthen the case for applied research studies to demonstrate that safe male circumcision is protective at the population level, particularly as ideal and well-resourced conditions of a randomized trial are often not replicated in other service delivery settings. Ethically and culturally responsive strategies in promoting circumcision in a culturally heterogenous world need to be developed, too. Male circumcision should also be viewed as a complementary measure along with other proven approaches to turn the HIV/AIDS epidemic around.

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