MRI-Guided Transurethral Ultrasound Ablation of Prostate Cancer: A Systematic Review

2022 ◽  
Author(s):  
Chandler Dora ◽  
Gina M Clarke ◽  
Gregory Frey ◽  
David Sella
2020 ◽  
pp. 028418512097693
Author(s):  
Pietari Mäkelä ◽  
Mikael Anttinen ◽  
Visa Suomi ◽  
Aida Steiner ◽  
Jani Saunavaara ◽  
...  

Background Magnetic resonance imaging (MRI)-guided transurethral ultrasound ablation (TULSA) is an emerging method for treatment of localized prostate cancer (PCa). TULSA-related subacute MRI findings have not been previously characterized. Purpose To evaluate acute and subacute MRI findings after TULSA treatment in a treat-and-resect setting. Material and Methods Six men with newly diagnosed MRI-visible and biopsy-concordant clinically significant PCa were enrolled and completed the study. Eight lesions classified as PI-RADS 3–5 were focally ablated using TULSA. One- and three-week follow-up MRI scans were performed between TULSA and robot-assisted laparoscopic prostatectomy. Results TULSA-related hemorrhage was detected as a subtle T1 hyperintensity and more apparent T2 hypointensity in the MRI. Both prostate volume and non-perfused volume (NPV) markedly increased after TULSA at one week and three weeks after treatment, respectively. Lesion apparent diffusion coefficient values increased one week after treatment and decreased nearing the baseline values at the three-week MRI follow-up. Conclusion The optimal timing of MRI follow-up seems to be at the earliest at three weeks after treatment, when the post-procedural edema has decreased and the NPV has matured. Diffusion-weighted imaging has little or no added diagnostic value in the subacute setting.


2019 ◽  
Vol 201 (Supplement 4) ◽  
Author(s):  
Scott Eggener* ◽  
David Penson ◽  
Christian Pavlovich ◽  
Joseph Chin ◽  
Steven S. Raman ◽  
...  

2021 ◽  
Vol 206 (Supplement 3) ◽  
Author(s):  
Laurence Klotz ◽  
Christian P. Pavlovich ◽  
Joseph Chin ◽  
Gencay Hatiboglu ◽  
Michael Koch ◽  
...  

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