scholarly journals 692 Does Sleep Laterality Influence Kidney Stone Formation and Clearance? – A Review of The Current Literature

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
J W Yun ◽  
L Saada

Abstract Introduction Stone disease is a common urological presentation that carries significant morbidity. Patients with renal calculi often experience ipsilateral recurrences. Sleep posture has been implicated in conditions ranging from heart failure to glaucoma. We seek a consensus view on the association between sleep laterality and stone disease and discuss its possible clinical implications. Method A literature search was conducted on the PubMed database from its inception through to September 2020. Publications assessing the correlation between sleep laterality and unilateral stone formation or clearance were included. 19 results were identified, of which 13 were excluded due to irrelevance. Results A review of the literature suggests that sleep laterality is positively correlated with ipsilateral stone formation. Interestingly, a study examining the interaction between sleep laterality and stone clearance following shock wave lithotripsy showed greater clearance of stones in patients who slept on the ipsilateral side. Conclusions Sleep laterality may positively influence both the formation and clearance of unilateral kidney stones. The mechanism for this remains unclear. However, sleep posture aids may prove to be a low-cost intervention with potential for both preventative and therapeutic benefit. This would be of particular value in patients with recurrent unilateral stone disease as well as those with a single-functioning kidney.

2012 ◽  
Vol 584 ◽  
pp. 504-508 ◽  
Author(s):  
Deeptiman Chatterjee ◽  
Vishaka Verma ◽  
Amiti ◽  
Sheija Rohil ◽  
Narayanasamy Arunai Nambi Raj ◽  
...  

Kidney stones or renal calculi or Nephrolithiasis is a common health problem in both developed and developing nations [1,2]. Analysis of the chemical and physical properties of renal calculi helps in preventing their formation and treatment. In this study, we evaluated the hardness of water used for drinking purposes, in an attempt to correlate water hardness with an increased incidence of stone formation. Identifying risk factors help to develop a preventive strategy to reduce the risk of renal calculi formation. The incidence of kidney stone formation in Vellore district was correlated with the hardness of water samples taken from different areas in Vellore. The study can be employed at a larger demographic level for effective and economic monitoring of the risk of kidney stone formation.


1998 ◽  
Vol 9 (9) ◽  
pp. 1645-1652
Author(s):  
G C Curhan ◽  
W C Willett ◽  
E B Rimm ◽  
F E Speizer ◽  
M J Stampfer

A variety of factors influence the formation of calcium oxalate kidney stones, including gender, diet, and urinary excretion of calcium, oxalate, and uric acid. Several of these factors may be related to body size. Because men on average have a larger body size and a threefold higher lifetime risk of stone formation than women, body size may be an important risk factor for calcium oxalate stone formation. The association between body size (height, weight, and body mass index) and the risk of kidney stone formation was studied in two large cohorts: the Nurses' Health Study (NHS; n = 89,376 women) and the Health Professionals Follow-up Study (HPFS; n = 51,529 men). Information on body size, kidney stone formation, and other exposures of interest was obtained by mailed questionnaires. A total of 1078 incident cases of kidney stones in NHS during 14 yr of follow-up and a total of 956 cases in HPFS during 8 yr of follow-up were confirmed. In both cohorts, the prevalence of a stone disease history and the incidence of stone disease were directly associated with weight and body mass index. However, the magnitude of the associations was consistently greater among women. Specifically, the age-adjusted prevalence odds ratio for women with body mass index > or = 32 kg/m2 compared with 21 to 22.9 kg/m2 was 1.76 (95% confidence interval, 1.50 to 2.07), but 1.38 (95% confidence interval, 1.16 to 1.65) for the same comparison in men. For incident stone formation, the multivariate relative risks for the similar comparisons were 1.89 (1.51 to 2.36) for women and 1.19 (0.83 to 1.70) in men. Height was inversely associated with the prevalence of stone disease but was not associated with incident stone formation. These results suggest that body size is associated with the risk of stone formation and that the magnitude of risk varies by gender. Additional studies are necessary to determine whether a reduction in body weight decreases the risk of stone formation, particularly in women.


Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1917
Author(s):  
Roswitha Siener

The prevalence of kidney stone disease is increasing worldwide. The recurrence rate of urinary stones is estimated to be up to 50%. Nephrolithiasis is associated with increased risk of chronic and end stage kidney disease. Diet composition is considered to play a crucial role in urinary stone formation. There is strong evidence that an inadequate fluid intake is the major dietary risk factor for urolithiasis. While the benefit of high fluid intake has been confirmed, the effect of different beverages, such as tap water, mineral water, fruit juices, soft drinks, tea and coffee, are debated. Other nutritional factors, including dietary protein, carbohydrates, oxalate, calcium and sodium chloride can also modulate the urinary risk profile and contribute to the risk of kidney stone formation. The assessment of nutritional risk factors is an essential component in the specific dietary therapy of kidney stone patients. An appropriate dietary intervention can contribute to the effective prevention of recurrent stones and reduce the burden of invasive surgical procedures for the treatment of urinary stone disease. This narrative review has intended to provide a comprehensive and updated overview on the role of nutrition and diet in kidney stone disease.


2021 ◽  
pp. 105257
Author(s):  
Narjess Bostanghadiri ◽  
Pardis Ziaeefar ◽  
Fatemeh Sameni ◽  
Mohammad Mahmoudi ◽  
Ali Hashemi ◽  
...  

Author(s):  
Raymundo Alejandro Pérez-Hernández ◽  
Silvia Guadalupe Treviño-Moreno ◽  
Gilberto Arévalo- Martínez ◽  
Eduardo Sánchez -García ◽  
Catalina Leos-Rivas ◽  
...  

Background: In clinical therapy, there is no satisfactory drug available for treatment of urolithiasis, especially for the prevention of their recurrence. The aim of this work was to evaluate in vivo antiurolithic activity of methanolic extract of Berberis trifoliata leaves. Material and methods: Urolithiasis was induced in Wistar rats by zinc disc implantation in urinary bladder. Upon postsurgical recovery, different doses of the methanolic extract of B. trifoliata leaves (50, 100 and 150 mg/kg body weight) were administered orally to zinc disc implanted rats for a period of 20 days. Antiurolithiatic activity was evaluated by measuring the difference between the weight of the implanted zinc discs at the time of implantation and the final weight of the dried calculi taken out from the bladder at the end of the 20 days period of treatment. Results: Extract of B. trifoliata significantly reduced calculi deposition around the implanted zinc disc at all doses (50, 100, and 150 mg/kg). Conclusion: Treatment with methanolic extract of B. trifoliata is useful agent against the kidney stone formation.


2016 ◽  
Vol 195 (4S) ◽  
Author(s):  
Andrew Cohen ◽  
Melanie Adamsky ◽  
Charles Nottingham ◽  
Jaclyn Pruitt ◽  
Brittany Lapin ◽  
...  

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