scholarly journals 1447 Trends in Lower Extremity Amputation Incidence in European Union 15+ Countries 1990-2017

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
R Goodall ◽  
W Hughes ◽  
J Salciccioli ◽  
D Marshall ◽  
A H Davies ◽  
...  
Keyword(s):  
European Union ◽  
Lower Extremity ◽  
Incidence Rates ◽  
Lower Extremity Amputation ◽  
Female Patients ◽  
Time Period ◽  
Male Patients ◽  
Increasing Trends ◽  
Extremity Amputation ◽  
Toe Amputation

Abstract Aim To assess trends in lower extremity amputation (LEA) incidence in European Union (EU15+) countries for the years 1990-2017. Method This was an observational study using data obtained from the 2017 Global Burden of Disease (GBD) Study. Age standardised incidence rates (ASIRs) for LEA (stratified into toe amputation, and LEA proximal to toes) were extracted from the GBD Results Tool (http://ghdx.healthdata.org/gbd-results-tool) for EU15+ countries for each of the years 1990-2017. Trends were analysed using Joinpoint regression analysis. Results Between 1990 and 2017, variable trends in the incidence of LEA were observed in EU15+ countries. For LEAs proximal to toes, increasing trends were observed in six of 19 countries and decreasing trends in nine of 19 countries, with four countries showing varying trends between sexes. For toe amputation, increasing trends were observed in eight of 19 countries and decreasing trends in eight of 19 countries for both sexes, with three countries showing varying trends between sexes. Australia had the highest ASIRs for both sexes in all LEAs at all time points, with steadily increasing trends. The USA observed the greatest reduction in all LEAs in both sexes over the time period analysed (LEAs proximal to toes: female patients 22.93%, male patients 29.76%; toe amputation: female patients 29.93%, male patients 32.67%). The greatest overall increase in incidence was observed in Australia. Conclusions Variable trends in LEA incidence were observed across EU15+ countries. These trends do not reflect previously observed reductions in incidence of PAOD over the same time period.

Temporal Trends in Cardiovascular Complications in People With or Without Type 2 Diabetes: The Fremantle Diabetes Study

2020 ◽  
Vol 105 (7) ◽  
pp. e2471-e2482 ◽  
Author(s):  
Wendy A Davis ◽  
Edward W Gregg ◽  
Timothy M E Davis
Keyword(s):  
Type 2 Diabetes ◽  
Lower Extremity ◽  
Proportional Hazards ◽  
Temporal Trends ◽  
Incidence Rates ◽  
Cox Proportional Hazards ◽  
Lower Extremity Amputation ◽  
All Cause Mortality ◽  
Extremity Amputation

Abstract Context There is evidence that diabetes-related complications are declining but most data sources have limitations. Objective To characterize temporal changes in incidence rates (IRs) of chronic complications and mortality in well-characterized, community-based Australians. Design Longitudinal observational study. Setting Urban population. Participants Participants with type 2 diabetes from the Fremantle Diabetes Study phases I (FDS1; n = 1291 recruited 1993-1996) and II (FDS2; n = 1509 recruited 2008-2011) age-, sex,- and ZIP code-matched 1:4 to people without diabetes. Main outcome measures First hospitalizations for/with myocardial infarction (MI), stroke, heart failure (HF), lower extremity amputation, and cardiovascular disease (CVD) and all-cause mortality. Five-year IRs, IR ratios for those with versus without diabetes in FDS1 and FDS2, and IR differences (IRDs), were calculated. Results The 13,995 participants had a mean age of 64.8 years and 50.4% were males. There were lower IR ratios for MI, stroke, HF, and CVD death in FDS2 versus FDS1. IRDs for people with versus without type 2 diabetes had reduced by >50% between phases for MI, stroke, HF, lower extremity amputation, and CVD death, with no change in IRD for all-cause mortality. Within the pooled type 2 diabetes cohort, FDS2 versus FDS1 participation was an independent inverse predictor of stroke, HF, CVD death, and all-cause mortality after adjustment in Cox proportional hazards models. Conclusions Cardiovascular outcomes in Australians have improved since the 1990s, especially in type 2 diabetes. The difference in all-cause mortality between those with and without type 2 diabetes has persisted despite longer survival.

scholarly journals Editor's Choice – Trends in Lower Extremity Amputation Incidence in European Union 15+ Countries 1990–2017

2020 ◽  
Vol 60 (4) ◽  
pp. 602-612 ◽  
Author(s):  
Will Hughes ◽  
Richard Goodall ◽  
Justin D. Salciccioli ◽  
Dominic C. Marshall ◽  
Alun H. Davies ◽  
...  
Keyword(s):  
European Union ◽  
Lower Extremity ◽  
Lower Extremity Amputation ◽  
Extremity Amputation

Trends in Lower Extremity Amputation Incidence in European Union 15+ Countries 1990–2017

2020 ◽  
Vol 72 (5) ◽  
pp. 1818
Author(s):  
W. Hughes ◽  
R. Goodall ◽  
J.D. Salciccioli ◽  
D.C. Marshall ◽  
A.H. Davies ◽  
...  
Keyword(s):  
European Union ◽  
Lower Extremity ◽  
Lower Extremity Amputation ◽  
Extremity Amputation

Review of Research on Prosthetic Devices for Lower Extremity Amputation

2006 ◽  
Vol 34 (5) ◽  
pp. 379-438 ◽  
Author(s):  
Diane M. Collins ◽  
Amol Karmarkar ◽  
Rick Relich ◽  
Paul F. Pasquina ◽  
Rory A. Cooper
Keyword(s):  
Lower Extremity ◽  
Lower Extremity Amputation ◽  
Prosthetic Devices ◽  
Extremity Amputation

1497-P: Secular Trends in Incidence and One-Year Mortality Rates of Lower Extremity Amputation in People with Diabetes in Hong Kong between 2001 and 2016

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1497-P
Author(s):  
HONGJIANG WU ◽  
AIMIN YANG ◽  
ERIC S. LAU ◽  
RONALD C. MA ◽  
ALICE P. KONG ◽  
...  
Keyword(s):  
Hong Kong ◽  
Lower Extremity ◽  
Mortality Rates ◽  
Secular Trends ◽  
Lower Extremity Amputation ◽  
One Year ◽  
Extremity Amputation

Lower-extremity amputation. Incidence, risk factors, and mortality in the Oklahoma Indian Diabetes Study

Diabetes ◽  
1993 ◽  
Vol 42 (6) ◽  
pp. 876-882 ◽  
Author(s):  
J. S. Lee ◽  
M. Lu ◽  
V. S. Lee ◽  
D. Russell ◽  
C. Bahr ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lower Extremity ◽  
Lower Extremity Amputation ◽  
Incidence Risk ◽  
Extremity Amputation
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