scholarly journals Fulminant Myocarditis Following COVID-19 Vaccination: A Case Report

2022 ◽  
Author(s):  
Arianne Clare C Agdamag ◽  
Daniel Gonzalez ◽  
Katie Carlson ◽  
Suma Konety ◽  
William C McDonald ◽  
...  
Keyword(s):  
Mechanical Circulatory Support ◽  
Rare Complication ◽  
Stable Condition ◽  
Fulminant Myocarditis ◽  
Circulatory Support ◽  
Myocardial Inflammation ◽  
High Dose ◽  
High Morbidity ◽  
Case Summary ◽  
Clinical Benefits

Abstract Background The BNT162b2 vaccine received emergency use authorization from the U.S. Food and Drug Administration for the prevention of severe COVID-19 infection. We report a case of biopsy and MRI-proven severe myocarditis that developed in a previously healthy individual within days of receiving the first dose of the BNT162b2 COVID-19 vaccine. Case Summary An 80-year-old female with no significant cardiac history presented with cardiogenic shock and biopsy-proven fulminant myocarditis within 12 days of receiving the BNT162b2 COVID-19 vaccine. She required temporary mechanical circulatory support, inotropic agents and high-dose steroids for stabilization and management. Ultimately her cardiac function recovered, and she was discharged in stable condition after 2 weeks of hospitalization. A repeat cardiac MRI 3 months after her initial presentation demonstrated stable biventricular function and continued improvement in myocardial inflammation. Discussion Fulminant myocarditis is a rare complication of vaccination. Clinicians should stay vigilant to recognize this rare, but potentially deadly complication. Due to the high morbidity and mortality associated with COVID-19 infection, the clinical benefits of the BNT162b2 vaccine greatly outweighs the risks of complications.

Recent clinical outcome in children with acute fulminant myocarditis supported by mechanical circulatory support

2015 ◽  
Vol 30 (4) ◽  
pp. 852
Author(s):  
Hong ju Shin ◽  
Yu rim Shin ◽  
Han ki Park ◽  
Young hwan Park ◽  
Nam kyun Kim ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Mechanical Circulatory Support ◽  
Fulminant Myocarditis ◽  
Circulatory Support

Abstract 15170: In-hospital Utilization and Outcomes of Palliative Care Consultation in Patients With Advanced Heart Failure Complicated by Cardiogenic Shock Requiring Mechanical Circulatory Support

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Jelani Grant ◽  
Louis Vincent ◽  
Bertrand Ebner ◽  
Jennifer Maning ◽  
Igor Vaz ◽  
...  
Keyword(s):  
Heart Failure ◽  
Palliative Care ◽  
Cardiogenic Shock ◽  
Mechanical Circulatory Support ◽  
Life Experiences ◽  
Advanced Heart Failure ◽  
Circulatory Support ◽  
High Morbidity ◽  
Palliative Care Consultation ◽  
Care Consultation

Introduction: Hospitalizations associated with advanced heart failure (HF) requiring mechanical circulatory support (MCS) are usually associated with a high morbidity, mortality and a protracted hospital course. Prior studies have shown that the early inclusion of palliative care specialist is associated with better end-of-life experiences. Methods: The National Inpatient Sample Database was queried from 2012 to 2017 for relevant International Classification of Diseases (ICD)-9 and ICD-10 procedural and diagnostic codes to identify patients above 18 years with advanced HF admitted with cardiogenic shock requiring MCS. Baseline characteristics and in-hospital outcomes were compared among patients evaluated by palliative care and those who were not. A p-value of <0.001 was considered statistically significant. Results: There were 748,360 patients hospitalized for advanced HF complicated by cardiogenic shock requiring MCS, of these a palliative care consult was placed in 118,015 (15.8%) patients. Patients evaluated by palliative care were older (70.6±14.9 vs. 64.9±16.3 years old, p<0.001) and had a higher prevalence of atrial fibrillation (39.3 vs. 35.1%,p<0.001) and chronic kidney disease (40.4 vs. 33.3, p<0.001), however had lower hypertension (57.4 vs. 59.7%, p<0.001), diabetes (35.4 vs. 36.5%, p<0.001), coronary artery disease (51.2 vs. 58.4%, p<0.001) and acute coronary syndromes (39.2 vs. 45.0%, p<0.001). Consulting palliative care was associated with a shorter length of stay (8.8±12.0 vs. 11.9±15.5 days, p<0.001), lower total hospital cost ($161,972±265,156 vs. $219,114±318,387, p<0.001) and higher Do Not Resuscitate (DNR) orders (30.8 vs. 5.8%, p<0.001). Mortality rates were higher in the palliative care cohort (73.4 vs. 29.4%, p<0.001). Conclusions: Despite the high morbidity and mortality associated with advanced HF patients with cardiogenic shock requiring MCS, the overall prevalence of palliative care consultation is exceedingly low. DNR orders were more prevalent in patients seen by the palliative care service. This study highlights the underutilization of palliative care services in this patient population, precluding any perceived benefit in end of life experiences.

Risk Factors for Cardiac Arrest or Mechanical Circulatory Support in Children with Fulminant Myocarditis

2016 ◽  
Vol 38 (1) ◽  
pp. 128-134 ◽  
Author(s):  
Joseph R. Casadonte ◽  
Mjaye L. Mazwi ◽  
Katheryn E. Gambetta ◽  
Hannah L. Palac ◽  
Mary E. McBride ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiac Arrest ◽  
Mechanical Circulatory Support ◽  
Fulminant Myocarditis ◽  
Circulatory Support

scholarly journals Mechanical circulatory support for the treatment of children with acute fulminant myocarditis

2001 ◽  
Vol 122 (3) ◽  
pp. 440-448 ◽  
Author(s):  
Brian W. Duncan ◽  
Desmond J. Bohn ◽  
Andrew M. Atz ◽  
James W. French ◽  
Peter C. Laussen ◽  
...  
Keyword(s):  
Mechanical Circulatory Support ◽  
Fulminant Myocarditis ◽  
Circulatory Support

scholarly journals Atrial pacing and administration of nifekalant hydrochloride for unstable atrial fibrillation: a case report

2020 ◽  
Vol 4 (3) ◽  
pp. 1-5
Author(s):  
Daisuke Yakabe ◽  
Masahiro Araki ◽  
Kojiro Furukawa ◽  
Toshihiro Nakamura
Keyword(s):  
Atrial Fibrillation ◽  
Case Report ◽  
Hypertrophic Cardiomyopathy ◽  
Aortic Valve ◽  
Mechanical Circulatory Support ◽  
Rhythm Control ◽  
Circulatory Support ◽  
Atrial Pacing ◽  
Septal Myectomy ◽  
Case Summary

Abstract Background Atrial fibrillation (AF) is a common arrhythmia in patients with hypertrophic cardiomyopathy (HCM) and can deteriorate haemodynamic status. Case summary We report a case of a 77-year-old woman with cardiogenic shock due to paroxysmal AF, complicated with HCM and aortic stenosis. Atrial fibrillation was successfully managed with temporary atrial pacing and administration of nifekalant hydrochloride without invasive mechanical circulatory support until surgery. Septal myectomy, aortic valve replacement, and pulmonary vein isolation were performed. Discussion This case suggests that atrial pacing and nifekalant may be safe and effective for rhythm control.

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