scholarly journals Coronary artery calcification and cardiovascular risk factors in 3477 asymptomatic and symptomatic individuals

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P4694-P4694
Author(s):  
K. A. Oevrehus ◽  
J. Jasinskiene ◽  
N. P. R. Sand ◽  
J. M. Jensen ◽  
H. Munkholm ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Cardiovascular Risk Factors ◽  
Coronary Artery Calcification

Traditional Cardiovascular Risk Factors and Coronary Artery Calcification in Adults With Polymyositis and Dermatomyositis: A Danish Multicenter Study

2015 ◽  
Vol 67 (6) ◽  
pp. 848-854 ◽  
Author(s):  
Louise P. Diederichsen ◽  
Axel C. P. Diederichsen ◽  
Jane A. Simonsen ◽  
Peter Junker ◽  
Klaus Søndergaard ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Cardiovascular Risk Factors ◽  
Multicenter Study ◽  
Coronary Artery Calcification

Subclinical coronary atherosclerosis is more pronounced in men and women with lower socio-economic status: associations in a population-based study Coronary atherosclerosis and social status

2007 ◽  
Vol 14 (4) ◽  
pp. 568-574 ◽  
Author(s):  
Nico Dragano ◽  
Pablo Emilio Verde ◽  
Susanne Moebus ◽  
Andreas Stang ◽  
Axel Schmermund ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Cardiovascular Risk Factors ◽  
Coronary Artery Calcification ◽  
Coronary Atherosclerosis ◽  
Social Inequalities ◽  
Heart Diseases ◽  
Economic Status ◽  
Socio Economic Status

Background Social inequalities of manifest coronary heart diseases are well documented in modern societies. Less evidence is available on subclinical atherosclerotic disease despite the opportunity to investigate processes underlying this association. Therefore, we examined the relationship between coronary artery calcification as a sign of subclinical coronary atherosclerosis, socio-economic status and established cardiovascular risk factors in a healthy population. Design Cross-sectional. Methods In a population-based sample of 4487 men and women coronary artery calcification was assessed by electron beam computed tomography quantified by the Agatston score. Socio-economic status was assessed by two indicators, education and income. First, we investigated associations between the social measures and calcification. Second, we assessed the influence of cardiovascular risk factors on this association. Results After adjustment for age, men with 10 and less years of formal education had a 70% increase in calcification score compared with men with high education. The respective increase for women was 80%. For income the association was weaker (among men 20% higher for the lowest compared with the highest quartile; and among women 50% higher, respectively). Consecutive adjustment for cardiovascular risk factors significantly attenuated the observed association of socio-economic status with calcification. Conclusions Social inequalities in coronary heart diseases seem to influence signs of subclinical coronary atherosclerosis as measured by coronary artery calcification. Importantly, cumulation of major cardiovascular risk factors in lower socio-economic groups accounted for a substantial part of this association.

scholarly journals Prevalence of coronary artery calcification in young adults in UK

2021 ◽  
Vol 22 (Supplement_3) ◽  
Author(s):  
G Koulaouzidis
Keyword(s):  
Risk Factors ◽  
Computed Tomography ◽  
Young Adults ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Cardiovascular Risk Factors ◽  
Coronary Artery Calcification ◽  
Subclinical Atherosclerosis ◽  
Study Cohort ◽  
History Of

Abstract Funding Acknowledgements Type of funding sources: None. Background Coronary atherosclerosis is a continuous process beginning early in life, with a long and clinically asymptomatic phase, before manifestations appear in middle and/or late adulthood. Coronary artery calcification (CAC) is a well-established marker of atherosclerosis; but the clinical validity of CAC in young adults (traditionally considered as a population group of low cardiovascular risk) remains unclear. Aim We aimed to assess the prevalence of CAC in a population of young individuals without previous history of coronary artery disease (CAD) in the UK and its association with conventional cardiovascular risk factors. Methods This analysis includes 4186 asymptomatic young individuals who underwent electron beam computed tomography (EBCT). Demographic information and the presence of cardiovascular risk factors were abstracted from referral letters and/or questionnaires completed by the patients prior to their tests. Individuals with previously documented CAD or chronic kidney disease were excluded. All EBCT CAC studies were performed using the same scanner (Imatron C300 Ultrafast computed tomography scanner, GE Healthcare, London, UK) and the same scanning protocol. Results The age (mean SD) of the study cohort was 40.5 ±3.6 years (range 26–45 years, 83.8% males). Hypertension, dyslipidemia, and diabetes mellitus (DM) were present in 15.5, 7.9, and 2.8% of individuals, respectively. Family history of premature CAD was present in 17% and 17.4% were smokers.  CAC was present in 21.8% of the cohort, while individuals with CAC comparing with those with CAC score 0 were males (95.2 vs. 80%, p < 0.002), older in age (41.4 3.2 vs. 40.3 3.7 years, p < 0.0001), with DM (5.5 vs. 25%, p < 0.0001), hypertension (22 vs. 13.7%, p < 0.0001), and dyslipidemia (14.8 vs. 6%, p < 0.0001). The prevalence of CAC score 0, 1–100, 101–400, 401–1000, >1000 were 78.2, 19, 2.1, 0.5, and 0.2%, respectively. The prevalence and distribution of CAC among various age groups are shown in Table 1. CAC was found in 24.8% of males (CAC score 1–100, 101–400, 400–1000, >1000 in 21.6, 2.5, 0.5, and 0.1%, respectively) and 6.6% of females (CAC score 1–100, 101–400, 400–1000, >1000 in 5.4, 0.6, 0.15 and 0.4%, respectively) (p < 0.0001). There was no statistical difference of mean CAC score between genders (males 13.8 72.7; females 11.8 142.4; p = 0.6). In multivariate analysis, the presence of CAC was associated with age (p< 0.0001), male gender (p< 0.0001), DM (p< 0.0001), hypertension (p< 0.0001), and dyslipidemia (p< 0.0001).  Conclusion   In a large cohort of asymptomatic young individuals, subclinical atherosclerosis (CAC score >0) was identified in approximately 20%. Assessment of CAC score is a useful clinical tool in young individuals, as it can confirm the presence of subclinical atherosclerosis.

Association of Traditional and Nontraditional Cardiovascular Risk Factors with Coronary Artery Calcification

Angiology ◽  
2004 ◽  
Vol 55 (6) ◽  
pp. 613-623 ◽  
Author(s):  
Aaron R. Folsom ◽  
Gregory W. Evans ◽  
J. Jeffery Carr ◽  
Arthur E. Stillman ◽  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Cardiovascular Risk Factors ◽  
Coronary Artery Calcification
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