scholarly journals Epicardial adipose tissue and left atrial size as CT-derived predictors of atrial fibrillation: the heinz nixdorf recall study

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P5330-P5330
Author(s):  
A. A. Mahabadi ◽  
N. Lehmann ◽  
H. Kalsch ◽  
M. Bauer ◽  
I. Dykun ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Adipose Tissue ◽  
Left Atrial ◽  
Epicardial Adipose Tissue ◽  
Left Atrial Size ◽  
Heinz Nixdorf Recall Study ◽  
Atrial Size

scholarly journals Association of Epicardial Adipose Tissue Thickness with Left Atrial Size and Atrial Fibrillation

2021 ◽  
pp. 60-66
Author(s):  
Ahmed M. Abd ElSalam ◽  
Amany M. Allaithy ◽  
Mona Elsaedy ◽  
Ekram Sadek Said
Keyword(s):  
Atrial Fibrillation ◽  
Adipose Tissue ◽  
Left Atrial ◽  
Epicardial Adipose Tissue ◽  
Left Atrial Size ◽  
Operating Characteristics ◽  
Tissue Thickness ◽  
Epicardial Adipose Tissue Thickness ◽  
Atrial Size ◽  
Significant Difference

Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with detrimental consequences. Epicardial fat is consistently associated with the presence, severity, and recurrence of AF. Aim: The aim of the work was to investigate the association of epicardial adipose tissue thickness with left atrial size in patients with atrial fibrillation. Patients and Methods: This study was conducted on 25 atrial fibrillation (AF) patients and 25 subjects with normal sinus rhythm as a control group matched in body weight. All patients underwent transthoracic echocardiogram. EAT (epicardial adipose tissue) thickness was measured on the right ventricular free wall of the two- dimensional parasternal long-axis view at end systole.  Results: The results showed that there was a significant difference between the two groups in waist circumference, EAT (epicardial adipose tissue) thickness, left atrium diameter, LA volume. Receiver operating characteristics (ROC) analysis showed that an EAT thickness of > 0.30 cm maximizes the sensitivity and specificity to predict the development of AF. Conclusion: Increases epicardial adipose tissue is associated with the occurrence of atrial fibrillation.

scholarly journals Opposite relations of epicardial adipose tissue to left atrial size in paroxysmal and permanent atrial fibrillation

2018 ◽  
Vol 6 ◽  
pp. 205031211879990 ◽  
Author(s):  
Stavroula N Psychari ◽  
Dionysios Tsoukalas ◽  
Dimitrios Varvarousis ◽  
Anastasios Papaspyropoulos ◽  
Eleni Gkika ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Adipose Tissue ◽  
Interleukin 6 ◽  
Left Atrial ◽  
Epicardial Adipose Tissue ◽  
High Sensitivity ◽  
Left Atrial Size ◽  
Reactive Protein ◽  
Permanent Atrial Fibrillation ◽  
Atrial Size

Objectives: Atrial fibrillation has been associated with obesity in epidemiological studies. Epicardial adipose tissue is an ectopic fat depot in the proximity of atria, with endocrine and inflammatory properties that is implicated in the pathophysiology of atrial fibrillation. Inflammation also has a role in atrial arrhythmogenesis. The aim of this study was to investigate the potential relations of epicardial adipose tissue to left atrial size and to adiponectin and the pro-inflammatory mediators, high-sensitivity C-reactive protein, and interleukin-6 in paroxysmal and permanent atrial fibrillation. Methods: This was a cross-sectional study of 103 atrial fibrillation patients, divided into two subgroups of paroxysmal and permanent atrial fibrillation, and 81 controls, in sinus rhythm. Echocardiography was used for estimation of epicardial adipose tissue and left atrial size and high-sensitivity C-reactive protein, interleukin-6 and adiponectin were measured in all subjects. Results: Atrial fibrillation patients had significantly larger epicardial adipose tissue compared with controls (0.43 ± 0.17 vs 0.34 ± 0.17 cm, p = 0.002). Atrial fibrillation presence was independently related to epicardial adipose tissue thickness ( b = 0.09, p = 0.002). Opposite associations of epicardial adipose tissue with left atrial volume existed in atrial fibrillation subgroups; in the paroxysmal subgroup, epicardial adipose tissue was directly related to left atrial volume ( R = 0.3, p = 0.03), but in the permanent one the relation was inverse ( R = −0.7, p < 0.0001). Adiponectin, high-sensitivity C-reactive protein and interleukin-6 were elevated in both atrial fibrillation groups. Only interleukin-6 was related to epicardial adipose tissue size. Conclusion: Opposite associations of epicardial adipose tissue with left atrial size in paroxysmal and permanent Atrial fibrillation and elevated inflammatory markers, suggest a role of epicardial adipose tissue and inflammation in the fibrotic and remodeling process.

scholarly journals The Effect of Catheter Ablation on Left Atrial Size and Function for Patients with Atrial Fibrillation: An Updated Meta-Analysis

PLoS ONE ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. e0129274 ◽  
Author(s):  
Bin Xiong ◽  
Dan Li ◽  
Jianling Wang ◽  
Laxman Gyawali ◽  
Jinjin Jing ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Left Atrial ◽  
Meta Analysis ◽  
Left Atrial Size ◽  
Atrial Size ◽  
And Function

scholarly journals 312 Correlation between Atrial Fibrillation Burden and Changes in Indices of Left Atrial Size and Function

2020 ◽  
Vol 29 ◽  
pp. S174
Author(s):  
D. Makarious ◽  
A. Bhat ◽  
S. Khanna ◽  
H. Chen ◽  
A. Drescher ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Left Atrial ◽  
Left Atrial Size ◽  
Atrial Size ◽  
Atrial Fibrillation Burden ◽  
And Function

The association of left atrial size and occurrence of atrial fibrillation: A prospective cohort study from the Canadian Registry of Atrial Fibrillation

2004 ◽  
Vol 148 (4) ◽  
pp. 649-654 ◽  
Author(s):  
Ratika Parkash ◽  
Martin S. Green ◽  
Charles R. Kerr ◽  
Stuart J. Connolly ◽  
George J. Klein ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Left Atrial ◽  
Left Atrial Size ◽  
Atrial Size

scholarly journals HOLTER MONITORING AND ECHOCARDIOGRAPHY FOR PREDICTING THE EFFECTIVENESS OF PULMONARY VIEN ISOLATION IN PATIENTS WITH PAROXYSMAL AND PERSISTENT ATRIAL FIBRILLATION

2018 ◽  
Vol 7 (3) ◽  
pp. 12-23
Author(s):  
A. V. Tregubov ◽  
Yu. V. Shubik
Keyword(s):  
Atrial Fibrillation ◽  
Left Atrial ◽  
Persistent Atrial Fibrillation ◽  
Holter Monitoring ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Left Atrial Size ◽  
Ventricular Ejection Fraction ◽  
Atrial Size ◽  
The Impact

Aim. To evaluate the impact of the atrial ectopic activity and left ventricular diastolic dysfunction on predicting the effectiveness of pulmonary vein isolation (PVI) in patients with paroxysmal and persistent atrial fibrillation (AF).Methods. 54 patients with paroxysmal and persistent AF and the normal left ventricular ejection fraction were included in the study. Patients underwent Holter monitoring and echocardiography prior to the intervention to identify the predictors of successful PVI. The follow-up was 12 months after the indexed procedure. The effectiveness of treatment was assessed from the third month of the postoperative period. The criterion of the successful treatment was the absence of the AF paroxysms lasting more than 30 seconds, confirmed by Holter, diurnal and / or multi-day monitoring. The Student's t-test was used to assess the reliability of the differences between the variables characterizing the treatment results in the study groups. The discriminant analysis was performed to develop an algorithm that allows predicting the PVI result. A p value <0.05 was considered statistically significant.Results. Premature atrial contraction over 70 per hour can be considered as the predictor of the successful PVI in patients with normal left atrial size. The severe LA enlargement should be considered as a predictor of poor ablation efficacy. The obtained discriminant function allows predicting the effectiveness of PVI in patients with paroxysmal and persistent AF depending on Holter monitoring and echocardiography. Its sensitivity is high for both predicting success and failure of the intervention.Conclusion. Holter monitoring and echocardiography allow predicting the effectiveness of PVI. The intervention's efficacy in the groups of patients with severe LA enlargement and the combination of normal left atrial size with over 70 PAC per hour should be addressed in the further studies.

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