scholarly journals 461Alcohol use and anti-retroviral adherence among people living with HIV in ART centre of Nepal

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Upendra Dhungana ◽  
Durga Prasad Pahari ◽  
Amod Kumar Poudyal

Abstract Background Alcohol use is known to have higher prevalence among HIV infected individuals. Hazardous use of alcohol in many studies is negatively associated with the adherence to antiretroviral therapy. Use of alcohol and ART adherence among PLHIV is inadequately explored in Nepalese context. This study aimed at identifying the level of alcohol use and its relationship with adherence to ART among PLHIV. Methods A total of 205 PLHIV of age 18 years or more were randomly selected at a national ART centre of Nepal. Self-reported adherence questionnaire was used to get the level of adherence, Alcohol Use Disorder Identification Test (AUDIT) with five questions was adopted for screening the hazardous alcohol use. Those who took more than 95% of the prescribed doses were considered as adherent. Results About 86% of the respondents were adherent to ART in four days recall. About one third of the respondents were alcohol user and 40% of them had hazardous use of alcohol. Those having hazardous use of alcohol were four times (AOR=4.60, 95% CI 1.27,16.62) more likely to be non-adherent as compared to those who had not hazardous use of alcohol. Multivariate analyses adjusted ethnicity, Knowledge on dangers of non-adherence, subjective feeling of own health, use of memory aid, IDU background, treatment substitution and depression category. Conclusion Hazardous use of alcohol was independently associated with non-adherence with the ART. Key message Screening at the start of the treatment and intervention targeting alcohol use may improve HIV outcomes in individuals with hazardous alcohol use.

PLoS ONE ◽  
2014 ◽  
Vol 9 (12) ◽  
pp. e113122 ◽  
Author(s):  
María José Míguez-Burbano ◽  
Clery Quiros ◽  
John E. Lewis ◽  
Luis Espinoza ◽  
Robert Cook ◽  
...  

2021 ◽  
pp. 095646242110144
Author(s):  
Mayuko Takamiya ◽  
Kudawashe Takarinda ◽  
Shrish Balachandra ◽  
Musuka Godfrey ◽  
Elizabeth Radin ◽  
...  

We assessed the prevalence of isoniazid preventive therapy (IPT) uptake and explored factors associated with IPT non-uptake among people living with HIV (PLHIV) using nationally representative data from the Zimbabwe Population-based HIV Impact Assessment (ZIMPHIA) 2015–2016. This was a cross-sectional study of 3418 PLHIV ZIMPHIA participants eligible for IPT, aged ≥15 years and in HIV care. Logistic regression modeling was performed to assess factors associated with self-reported IPT uptake. All analyses accounted for multistage survey design. IPT uptake among PLHIV was 12.7% (95% confidence interval (CI): 11.4–14.1). After adjusting for sex, age, rural/urban residence, TB screening at the last clinic visit, and hazardous alcohol use, rural residence was the strongest factor associated with IPT non-uptake (adjusted OR (aOR): 2.39, 95% CI: 1.82–3.12). Isoniazid preventive therapy non-uptake having significant associations with no TB screening at the last HIV care (aOR: 2.07, 95% CI: 1.54–2.78) and with hazardous alcohol use only in urban areas (aOR: 10.74, 95% CI: 3.60–32.0) might suggest suboptimal IPT eligibility screening regardless of residence, but more so in rural areas. Self-reported IPT use among PLHIV in Zimbabwe was low, 2 years after beginning national scale-up. This shows the importance of good TB screening procedures for successful IPT implementation.


Author(s):  
Sean McCormick ◽  
Kathleen M Ward ◽  
Catherine G Sutcliffe ◽  
Risha Irvin ◽  
Geetanjali Chander ◽  
...  

Abstract Drug use, hazardous alcohol use, and mental health disorders are prevalent among people with HIV and HCV infection. Co-occurrence of alcohol use and depression negatively impacts substance use patterns. Nevertheless, HCV treatment provides a promising opportunity to identify and address co-occurring drug use, hazardous alcohol use, and mental health disorders.


AIDS ◽  
2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Jennifer A. Wagman ◽  
Adriane Wynn ◽  
Mika Matsuzaki ◽  
Natalia Gnatienko ◽  
Lisa R. Metsch ◽  
...  

2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Catherine O. Egbe ◽  
Patrick S. Dakum ◽  
Ernest Ekong ◽  
Brandon A. Kohrt ◽  
John G. Minto ◽  
...  

2020 ◽  
Author(s):  
Mogesie Necho ◽  
Asmare Belete ◽  
Yibeltal Getachew

Abstract Background Alcohol use disorder among people living with HIV/AIDS contributes to decreased adherence and effectiveness of antiretroviral medication, decreased help-seeking to HIV/AIDS care and treatment, increased load of the virus in the blood, and development of drug-resistant HIV strains. This study therefore aimed and assessed the pooled evidence on prevalence and associated factors of alcohol use disorder in retroviral infected patients in Africa. Methods We implemented our electronic data base search on PubMed, Scopus, EMBASE, and Psych-INFO libraries. In addition, WHO websites and Google scholar were also investigated for grey literatures. Moreover, we further investigated the reference lists of published articles. Stata-11meta-prop package with 95% confidence interval was used. Subgroup and sensitivity analysis were also performed. Cochran's Q- and the I2 test were used to check heterogeneity. Publication bias was evaluated with Egger's test and funnel plots. Results In this meta-analysis, we included 22 studies with a total of 16774 patients and the pooled prevalence of alcohol use disorder was 22.03%( 95% CI: 17.18, 28.67). The average prevalence of AUD in South Africa (28.77%) was higher than in Uganda (16.61%) and Nigeria (22.8%). Besides, the average prevalence of AUD in studies published before 2011, 2011–2015, and after 2015 was found to be 13.47%, 24.93% and 22.88% respectively. Moreover, the pooled magnitude of AUD among studies which utilized a sample size > 450 was 16.71% whereas it was 26.46% among studies that utilized sample size < 450. Furthermore, the pooled estimated prevalence of hazardous, harmful and dependent drinking was 10.87%, 8.1%, and 3.12% respectively. Being male was an associated factor for alcohol use disorder (AOR = 5.5%; 95% CI: 1.10, 9.98). Moreover, the average odds ratio of cigarette smoking and chat chewing were found to be 3.95% (95% CI: 3.00, 4.89) and 3.34% (95% CI: 1.71, 4.96) respectively. Conclusion The average estimated prevalence of AUD in HIV/AIDs patients was high and factors such as being Male, cigarette smoking and chat chewing were associated with it. Early detection and appropriate management of AUD and the mentioned associated factors have to be a routine practice.


2019 ◽  
Author(s):  
Bereket Beyene Gebre

Abstract Abstract Objective: To assess the magnitude of alcohol use and factors among HIV/AIDS positive adults visiting ART clinic at Mizan Tep university Teaching Hospital (MTUTH), Southern Ethiopia from October 2017 to December 2017. Result: A total of 332 participants were enrolled in the study with the prevalence of alcohol use disorder (AUD) of 18.4%. Factors associated with alcohol use disorder were sex AOR=3.48 (95%CI: 1.27, 9.59), cigarette smoking AOR=5.12(95%CI:4.02,8.61), “Khat” chewing AOR=3.23(95%CI: 2.06,6.89),and CD4 count of 0-200 AOR = 19.49 (95% CI:1.74 ,218.4). Key words:-Magnitude, Alcohol use disorder, factors.


2016 ◽  
Vol 12 (11) ◽  
pp. 241
Author(s):  
James E. Effiong ◽  
Okokon O. Umoh ◽  
Adedeji J. Ogunleye

A convenient sampling technique was used to draw a sample of 110 pregnant women reporting for antenatal clinical checks in both private and public medical facilities in Uyo, Nigeria to investigate marital satisfaction and age as predictors of alcohol use during pregnancy. Kansas Marital Satisfaction Scale was used in dichotomizing respondents into satisfied and dissatisfied pregnant women in marriage, while an item in Alcohol Use Disorder Identification Test (AUDIT) delineated our cohorts into users and non-users of alcohol. A 2x2 factorial design was adopted as regards the plan of the study while a 2-way analysis of variance was used for the analysis of data collected. Results confirmed the first hypothesis which predicted that pregnant women who are satisfied in their marriages would report less alcohol use than their dissatisfied counterparts {F (1, 104) = 4.70; p < .05}. Findings also confirmed our second hypothesis which stated that pregnant women who are younger would report more alcohol use than their elderly counterparts {F (5, 104) = 11.833; p, <.05}. Discussion of findings centered on the theories of learning which formed the nucleus of this paper and it was recommended that intervention would benefit from effective and affordable psychological counseling and treatment services for women exposed to harmful and/or hazardous alcohol use predicated by marital distress, violence, depression as well as those with limited coping skills.


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