scholarly journals Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study

2016 ◽  
Vol 214 (5) ◽  
pp. 762-771 ◽  
Author(s):  
Jason A. Regules ◽  
Susan B. Cicatelli ◽  
Jason W. Bennett ◽  
Kristopher M. Paolino ◽  
Patrick S. Twomey ◽  
...  
Keyword(s):  
Malaria Parasite ◽  
Parasite Infection ◽  
Candidate Vaccine ◽  
Human Malaria Parasite ◽  
Human Malaria ◽  
Malaria Parasite Infection ◽  
Fourth Dose ◽  
Immunogenicity Study

scholarly journals Development of humanized mouse models to study human malaria parasite infection

2012 ◽  
Vol 7 (5) ◽  
pp. 657-665 ◽  
Author(s):  
Ashley M Vaughan ◽  
Stefan HI Kappe ◽  
Alexander Ploss ◽  
Sebastian A Mikolajczak
Keyword(s):  
Mouse Models ◽  
Malaria Parasite ◽  
Parasite Infection ◽  
Humanized Mouse ◽  
Human Malaria Parasite ◽  
Human Malaria ◽  
Malaria Parasite Infection ◽  
Humanized Mouse Models

scholarly journals Aquatic Exposure to Abscisic Acid Transstadially Enhances Anopheles stephensi Resistance to Malaria Parasite Infection

Genes ◽  
2020 ◽  
Vol 11 (12) ◽  
pp. 1393
Author(s):  
Dean M. Taylor ◽  
Reagan S. Haney ◽  
Shirley Luckhart
Keyword(s):  
Abscisic Acid ◽  
Malaria Parasite ◽  
Anopheles Stephensi ◽  
Impact Resistance ◽  
Parasite Infection ◽  
Larval Rearing ◽  
Human Malaria Parasite ◽  
Malaria Parasite Infection ◽  
Immature Development ◽  
Mammalian Blood

The ancient stress signaling molecule abscisic acid (ABA) is ubiquitous in animals and plants but is perhaps most well-known from its early discovery as a plant hormone. ABA can be released into water by plants and is found in nectar, but is also present in mammalian blood, three key contexts for mosquito biology. We previously established that addition of ABA to Anopheles stephensi larval rearing water altered immature development and life history traits of females derived from treated larvae, while addition of ABA to an infected bloodmeal increased resistance of adult female A. stephensi to human malaria parasite infection. Here we sought to determine whether larval treatment with ABA could similarly impact resistance to parasite infection in females derived from treated larvae and, if so, whether resistance could be extended to another parasite species. We examined nutrient levels and gene expression to demonstrate that ABA can transstadially alter resistance to a rodent malaria parasite with hallmarks of previously observed mechanisms of resistance following provision of ABA in blood to A. stephensi.

scholarly journals Plasmodium knowlesi: An Important Yet Overlooked Human Malaria Parasite

2009 ◽  
Vol 84 (7) ◽  
pp. 664
Author(s):  
Balaji Yegneswaran ◽  
David Alcid ◽  
Janani Mohan
Keyword(s):  
Malaria Parasite ◽  
Plasmodium Knowlesi ◽  
Human Malaria Parasite ◽  
Human Malaria

Molecular Interaction of Ferredoxin and Ferredoxin-NADP+ Reductase from Human Malaria Parasite

2007 ◽  
Vol 142 (6) ◽  
pp. 715-720 ◽  
Author(s):  
Y. Kimata-Ariga ◽  
T. Saitoh ◽  
T. Ikegami ◽  
T. Horii ◽  
T. Hase
Keyword(s):  
Molecular Interaction ◽  
Malaria Parasite ◽  
Human Malaria Parasite ◽  
Human Malaria

Commitment to sexual differentiation in the human malaria parasite, Plasmodium falciparum

Parasitology ◽  
2000 ◽  
Vol 121 (2) ◽  
pp. 127-133 ◽  
Author(s):  
T. G. SMITH ◽  
P. LOURENÇO ◽  
R. CARTER ◽  
D. WALLIKER ◽  
L. C. RANFORD-CARTWRIGHT
Keyword(s):  
Plasmodium Falciparum ◽  
Sexual Differentiation ◽  
Malaria Parasite ◽  
Human Malaria Parasite ◽  
Human Malaria ◽  
Parasite Plasmodium ◽  
Parasite Plasmodium Falciparum
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