scholarly journals BT-05 A CASE OF GLIOMATOSIS CEREBRI WITH TOTAL SPINAL CORD EXTENSION

2019 ◽  
Vol 1 (Supplement_2) ◽  
pp. ii37-ii37
Author(s):  
Yasuyoshi Chiba ◽  
Osamu Takemoto ◽  
Junji Yamada ◽  
Takaki Matsumura
Keyword(s):  
Spinal Cord ◽  
Cerebral Hemisphere ◽  
Tumor Volume ◽  
Spinal Cord Tumor ◽  
Gliomatosis Cerebri ◽  
Eye Enucleation ◽  
Left Cerebral Hemisphere ◽  
First Occurrence ◽  
History Of ◽  
Important Disease

Abstract INTRODUCTION Although gliomatosis cerebri is no longer a pathological diagnostic name, it is still an important disease state as a gliomatosis cerebri growth pattern. Here we report a case of gliomatosis cerebri originating from the left cerebral hemisphere that developed whole spinal cord. CASE A 10-year-old boy. He has a history of 13q-syndrome and left retinoblastoma. Left eye enucleation and chemotherapy (modified 98A1) have been performed. MRI in July 2017 showed no abnormalities, but in September 2018, he developed epilepsy. MRI revealed a gliomatosis cerebri that spreads extensively in the left cerebral hemisphere. Biopsy revealed anaplastic astrocytoma (MIB-1 LI; 22%, IDH1 / 2; WT, TERT C228T mutation positive) and IMRT (59.4Gy) and temozolomide (Stupp regimen) were performed in December 2018. In June 2019, neck pain developed. Head and neck MRI revealed that the tumor in the head increased lightly, and there was no suspicion of tumor growth in the brainstem, but the tumor progressed to the entire spinal cord. Therefore, radiation therapy was started from the lower brainstem that had not been irradiated last time to the entire spinal cord, and administration of bevacizumab was started. DISCUSSION Based on the single cell origin theory, the left hemisphere tumor and spinal cord tumor should be continuous. Since gliomatosis cerebri is visualized on MRI only after the tumor volume has increased and edema has occurred, it may appear as if there is no tumor in between. The spinal cord MRI was not taken, so it is only speculation, but it seems that tumor cells had probably infiltrated the spinal cord from the beginning, and it seems that it gradually increased because it was not irradiated. Considering the possibility of remote invasion as in this case, it is necessary to consider taking MRI of spinal cord at the first occurrence.

Cerebral Malignant Tumors with Ependymal and Choroidal Differentiation in Two Siblings

Neurosurgery ◽  
1988 ◽  
Vol 22 (5) ◽  
pp. 928-933 ◽  
Author(s):  
David G. Munoz ◽  
Robert Griebel ◽  
Bohdan Rozdilsky ◽  
David George
Keyword(s):  
Choroid Plexus ◽  
Posterior Fossa ◽  
Cerebral Hemisphere ◽  
Malignant Tumors ◽  
Rare Tumor ◽  
Choroid Plexus Epithelium ◽  
Left Cerebral Hemisphere ◽  
Inherited Predisposition ◽  
History Of ◽  
Immunocytochemical Studies

Abstract Two siblings in a family without a history of phacomatosis or cerebral tumors developed malignant tumors in the posterior fossa at age 28 months and in the left cerebral hemisphere at age 15 months, respectively. Dual ependymal and choroid plexus epithelium differentiation was established by histological, ultrastructural, and immunocytochemical studies. The development of this rare tumor in siblings suggests an inherited predisposition, a common environmental insult, or both.

scholarly journals Neuro-muscular rehabilitation approach with favorable results in a case of a tetraplegia after a cervical ganglioneuroma – case presentation

2020 ◽  
pp. 530-532
Author(s):  
Cristina POPESCU ◽  
Mihai BAILA ◽  
Cristina DAIA ◽  
Ioana ANDONE ◽  
Daniel SERBAN ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Daily Living ◽  
Spinal Cord Tumor ◽  
Cord Compression ◽  
Rehabilitation Program ◽  
Traumatic Spinal Cord Injury ◽  
Case Presentation ◽  
Cord Injury ◽  
History Of

This is the case of a 52-year-old male patient with tetraplegia and muscle respiratory failure, due to an extradural compressive cervical ganglioneuroma (C1-C2), with a history of neurological symptoms for 3 years. The tumor was completely surgically removed and the patient followed a neuro-muscular rehabilitation program (NMRP) for 4 months, consisting of rehabilitation nursing, physical and occupational therapy. At the end of NMRP the patient’s achievements were: unilateral supported walking, partial autonomous daily living functioning, the improvement of quality of life and facilitation of social and professional participation. Keywords: ganglioneuroma, spinal cord tumor, neuro-muscular rehabilitation program, non-traumatic spinal cord injury, spinal cord compression,

Microsurgical resection of intramedullary spinal cord ependymoma

2014 ◽  
Vol 37 (v2supplement) ◽  
pp. Video9
Author(s):  
Paul C. McCormick
Keyword(s):  
Spinal Cord ◽  
Growth Rate ◽  
Spinal Cord Tumor ◽  
Intramedullary Spinal Cord ◽  
Clear Margin ◽  
Intramedullary Spinal Cord Tumor ◽  
Link Type ◽  
Microsurgical Resection ◽  
Spinal Cord Ependymoma ◽  
Posterior Midline

Ependymomas are the most commonly occurring intramedullary spinal cord tumor in adults. With few exceptions these tumors are histologically benign, although they exhibit some biologic variability with respect to growth rate. While unencapsulated, spinal ependymomas are non-infiltrative and present a clear margin of demarcation from the surrounding spinal cord that serves as an effective dissection plane. This video demonstrates the technique of microsurgical resection of an intramedullary ependymoma through a posterior midline myelotomy.The video can be found here: http://youtu.be/lcHhymSvSqU.

scholarly journals Autonomic dysreflexia associated with cervical spinal cord gliofibroma: case report

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hiroyuki Mizuno ◽  
Fumiaki Honda ◽  
Hayato Ikota ◽  
Yuhei Yoshimoto
Keyword(s):  
Spinal Cord ◽  
Cervical Spinal Cord ◽  
Spinal Cord Tumor ◽  
Autonomic Dysreflexia ◽  
Tumor Biopsy ◽  
Intramedullary Lesion ◽  
First Case ◽  
Cord Injury ◽  
Paroxysmal Hypertension ◽  
Upper And Lower Extremities

Abstract Background Autonomic dysreflexia (AD) is an abnormal reflex of the autonomic nervous system normally observed in patients with spinal cord injury from the sixth thoracic vertebra and above. AD causes various symptoms including paroxysmal hypertension due to stimulus. Here, we report a case of recurrent AD associated with cervical spinal cord tumor. Case presentation The patient was a 57-year-old man. Magnetic resonance imaging revealed an intramedullary lesion in the C2, C6, and high Th12 levels. During the course of treatment, sudden loss of consciousness occurred together with abnormal paroxysmal hypertension, marked facial sweating, left upward conjugate gaze deviation, ankylosis of both upper and lower extremities, and mydriasis. Seizures repeatedly occurred, with symptoms disappearing after approximately 30 min. AD associated with cervical spinal cord tumor was diagnosed. Histological examination by tumor biopsy confirmed the diagnosis of gliofibroma. Radiotherapy was performed targeting the entire brain and spinal cord. The patient died approximately 3 months after treatment was started. Conclusions AD is rarely associated with spinal cord tumor, and this is the first case associated with cervical spinal cord gliofibroma. AD is important to recognize, since immediate and appropriate response is required.

scholarly journals Intraoperative 3T MR Imaging for Spinal Cord Tumor Resection: Feasibility, Timing, and Image Quality Using a “Twin” MR–Operating Room Suite

2008 ◽  
Vol 29 (10) ◽  
pp. 1991-1994 ◽  
Author(s):  
T.P. Duprez ◽  
A. Jankovski ◽  
C. Grandin ◽  
L. Hermoye ◽  
G. Cosnard ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Image Quality ◽  
Mr Imaging ◽  
Operating Room ◽  
Spinal Cord Tumor ◽  
Tumor Resection ◽  
3T Mr

Infantile Spinal Cord Tumor: Diagnostic Difficulties. A Case Report

2002 ◽  
Vol 11 (1) ◽  
pp. 1-5
Author(s):  
Taichi Tsuji ◽  
Yukihiro Matsuyama ◽  
Koji Sato ◽  
Hisashi Iwata
Keyword(s):  
Spinal Cord ◽  
Case Report ◽  
Spinal Cord Tumor ◽  
Diagnostic Difficulties

An upper thoracic spinal cord tumor presenting as hemifacial hyperhidrosis

2007 ◽  
Vol 68 (4) ◽  
pp. 461-463 ◽  
Author(s):  
Cumhur Kilinçer ◽  
Levent Öztürk ◽  
M. Kemal Hamamcioglu ◽  
Emre Altunrende ◽  
Sebahattin Çobanoglu
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Tumor ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal ◽  
Upper Thoracic
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