Large Body Movements on Video-Polysomnography are Associated with Daytime Dysfunction in Children with Restless Sleep Disorder

Abstract Restless sleep disorder (RSD) is a newly defined sleep related movement disorder characterized by large muscle movements (LMM) in sleep. We examined the sleep study, clinical characteristics, and daytime functioning in children with RSD and compared them to children with Periodic Limb Movement Disorder (PLMD) or Restless Legs Syndrome (RLS). Video polysomnography from 47 children with restless sleep was retrospectively reviewed for LMM and age- and sex- matched to 34 children with PLMD and 12 children with RLS. Data examined included PSG characteristics, ferritin, Pediatric Quality of Life (PedsQL), and Epworth Sleepiness Scores (ESS). Fourteen children met the clinical criteria for RSD with a LMM index of 5 or more per hour of sleep . Mean ESS was elevated in RSD patients compared to either the PLMD or RLS groups though the result did not reach statistical significance (RSD = 10.20 ± 6.81, PLMD = 6.19 ± 4.14, RLS = 6.25 ± 4.90). The PedsQL score was significantly decreased in the RLS group compared to RSD and was reduced overall in all three groups (PedsQL Total RSD= 70.76 ± 18.05, PLMD = 57.05 ± 20.33, RLS = 53.24 ± 16.97). Serum ferritin values were similar in all three groups (RSD= 26.89 ± 10.29, PLMD = 33.91 ± 20.31, RLS = 23.69 ± 12.94 ng/mL, P= NS). Children with RSD demonstrate increased daytime sleepiness compared to PLMD or RLS and all three disease groups decreased quality of life. Further studies are needed to examine long term consequences of RSD.

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Surgical Repair of Ileovesical Fistulas: Long-term Complications, Quality of Life, and Patient Satisfaction

The American Surgeon ◽

10.1177/000313481408001221 ◽

2014 ◽

Vol 80 (12) ◽

pp. 1207-1211 ◽

Cited By ~ 3

Author(s):

Jeffrey W. Hastings ◽

Malika Garg ◽

Elizabeth T. Lynn ◽

Celia M. Divino

Keyword(s):

Quality Of Life ◽

Patient Satisfaction ◽

Statistical Significance ◽

Retrospective Chart Review ◽

Administrative Database ◽

Low Incidence ◽

Assess Quality

Ileovesical fistulas (IVFs) are an uncommon complication of Crohn's disease. The aim of this study is to compare long-term surgical outcomes, assess quality of life, and quantify patient satisfaction after IVF repair. A retrospective chart review followed by a prospective survey was carried out. Survey questions focused on patient satisfaction and quality of life after repair of IVF. Fifty-one patients were identified from an administrative database. Mean follow-up was 4.3 years with a response rate of 51 per cent. At the time of the study, 0 per cent mortality and 16 per cent morbidity were recorded. No recurrence was noted. There was no statistical significance in incidence of complications between laparoscopic and open surgery. Statistically significant differences in single-stage versus multistage operations were found in postoperative day of discharge ( P < 0.001) and patient satisfaction ( P = 0.049). Ninety-eight per cent of patients reported extreme satisfaction with their surgery and an improvement in quality of life. A low incidence of morbidity and recurrence supports early surgical intervention in IVFs.

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P6.048 Patient functional status/quality of life, safety,and tolerability with long-term modafinil in chronic shiftwork sleep disorder

European Neuropsychopharmacology ◽

10.1016/s0924-977x(04)80552-2 ◽

2004 ◽

Vol 14 ◽

pp. S376-S377

Author(s):

T. Roth ◽

C.A. Czeisler ◽

M.K. Erman ◽

J.K. Walsh ◽

J.R.L. Schwartz ◽

...

Keyword(s):

Quality Of Life ◽

Functional Status ◽

Sleep Disorder ◽

Life Safety

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586 Large Body Movements on Video-Polysomnography are Associated with Daytime Dysfunction in Children with Restless Sleep Disorder

SLEEP ◽

10.1093/sleep/zsab072.584 ◽

2021 ◽

Vol 44 (Supplement_2) ◽

pp. A231-A231

Author(s):

Wei Liu ◽

Dye Thomas ◽

Paul Horn ◽

David Garner ◽

Narong Simakajornboon

Keyword(s):

Quality Of Life ◽

Sleep Disorder ◽

Ferritin Level ◽

Large Body ◽

Sleep Onset ◽

Single Center ◽

Body Movements ◽

Nocturnal Sleep ◽

Quality Of Life Measures

Abstract Introduction Restless sleep disorder (RSD) is a recently described disorder of children and adolescents with complaints of restless sleep and is characterized by large body movements which interfere with nocturnal sleep, are associated with daytime dysfunction, and are not better explained by another disorder (1, 2). Polysomnography criteria for RSD includes the scoring of large body movements (LBMI) and identified an LBMI ≥ 5 as sensitive and specific for RSD. As data is currently limited to two pediatric centers, our study aims to identify RSD cases at our institution, characterize their PSG, and determine their effect on daytime dysfunction and quality of life. Methods This single center retrospective study included 41 children with complaints of restless sleep and 35 sex- and age-matched children with RLS/PLMD collected from February 2018 to November 2020. The video PSGs were re-scored utilizing the previously published criteria (1,3). We used two LBMI thresholds, LBMI ≥ 5 and an exploratory LBMI ≥ 4. We then compared Epworth Sleepiness Scores (ESS), Pediatric Quality of Life measures (PedsQL), PSG characteristics, LBM associated awakenings and ferritin level between groups. Results Twenty-one children (mean age=8.3 ± 3.13 SD) met the LBMI>=4 criteria, of which 11 (age=8.4±3.81 SD) met the LBMI>=5 criteria. All three groups reported decreased quality of life (PedsQL total LBMI>=4=66.21±20.28, LBMI>=5=72.39±18.24, RLS/PLMD=55.54±19.86), low mean ferritin values (LBMI>=4=33.18 ± 20.11, LBMI>=5 =28.38 ± 12.68, RLS/PLMD = 36.57±25.46), and increased wake after sleep onset (WASO) (LBMI>=4 = 42.82 ± 34.26, LBMI>=5=44.38 ± 38.4, RLS/PLMD = 52.34 ± 42.03), with no significant differences between groups. Both LBMI>=4 and LBMI>=5 groups exhibited higher ESS compared to the RLS/PLMD group (LBMI>=4=10.36±7.13; LBMI>=5=11.13±5.19; RLS/PLMD=6.17±4.04; LBMI>=4 vs RLS/PLMD, P=0.05; LBMI>=5 vs RLS/PLMD, P = 0.032). Both awakenings and WASO associated with LBM were high in LBMI>=4 and LBMI>=5 (Awakenings: LBMI>=4=8.43±9.96, LBMI>=5 =8.00±12.19, WASOassociatedLBM: LBMI>=4=23.60±44.64 LBMI>=5=29.46±57.57) Conclusion One quarter of children with complaints of restless sleep met the standard criteria for RSD. Both children with RSD (including the exploratory LBMI≥ 4 group) and RLS/PLMD had increased WASO, low ferritin and decreased quality of life, but the RSD group had more daytime sleepiness compared to RLS/PLMD. Support (if any):

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Thinking Beyond Language: Intervention for Severe Aphasia

Perspectives on Neurophysiology and Neurogenic Speech and Language Disorders ◽

10.1044/nnsld19.1.15 ◽

2009 ◽

Vol 19 (1) ◽

pp. 15-22 ◽

Cited By ~ 3

Author(s):

Nina Simmons-Mackie

Keyword(s):

Quality Of Life ◽

Communication Training ◽

Language Intervention ◽

Specific Training ◽

Environmental Support ◽

Total Communication ◽

Communication Partners

Abstract Purpose: This article addresses several intervention approaches that aim to improve life for individuals with severe aphasia. Because severe aphasia significantly compromises language, often for the long term, recommended approaches focus on additional domains that affect quality of life. Treatments are discussed that involve increasing participation in personally relevant life situations, enhancing environmental support for communication and participation, and improving communicative confidence. Methods: Interventions that have been suggested in the aphasia literature as particularly appropriate for people with severe aphasia include training in total communication, training of communication partners, and activity specific training. Conclusion: Several intervention approaches can be implemented to enhance life with severe aphasia.

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