Neuroprotective effects of a systemically active Group II metabotropic glutamate receptor agonist LY354740 in a gerbil model of global ischaemia

Ann Bond; Michael J. OʼNeill; Caroline A. Hicks; James A. Monn; David Lodge

doi:10.1097/00001756-199804200-00042

Neuroprotective effects of a systemically active Group II metabotropic glutamate receptor agonist LY354740 in a gerbil model of global ischaemia

Neuroreport ◽

10.1097/00001756-199804200-00042 ◽

1998 ◽

Vol 9 (6) ◽

pp. 1191-1193 ◽

Cited By ~ 58

Author(s):

Ann Bond ◽

Michael J. OʼNeill ◽

Caroline A. Hicks ◽

James A. Monn ◽

David Lodge

Keyword(s):

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Active Group ◽

Neuroprotective Effects ◽

Metabotropic Glutamate ◽

Global Ischaemia ◽

Group Ii ◽

Glutamate Receptor Agonist

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Neuroprotective effects of group II metabotropic glutamate receptor agonist DCG-IV on hippocampal neurons in transient forebrain ischemia

Neuroscience Letters ◽

10.1016/j.neulet.2009.06.056 ◽

2009 ◽

Vol 461 (3) ◽

pp. 266-270 ◽

Cited By ~ 7

Author(s):

Hideyuki Yoshioka ◽

Masao Sugita ◽

Hiroyuki Kinouchi

Keyword(s):

Glutamate Receptor ◽

Hippocampal Neurons ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Forebrain Ischemia ◽

Neuroprotective Effects ◽

Transient Forebrain Ischemia ◽

Metabotropic Glutamate ◽

Group Ii ◽

Glutamate Receptor Agonist

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LY379268, a potent and selective Group II metabotropic glutamate receptor agonist, is neuroprotective in gerbil global, but not focal, cerebral ischaemia

Neuroscience Letters ◽

10.1016/s0304-3940(99)00663-1 ◽

1999 ◽

Vol 273 (3) ◽

pp. 191-194 ◽

Cited By ~ 51

Author(s):

Ann Bond ◽

Nella Ragumoorthy ◽

James A. Monn ◽

Caroline A. Hicks ◽

Mark A. Ward ◽

...

Keyword(s):

Glutamate Receptor ◽

Cerebral Ischaemia ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Focal Cerebral Ischaemia ◽

Metabotropic Glutamate ◽

Group Ii ◽

Glutamate Receptor Agonist

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Reversal of Phencyclidine Effects by a Group II Metabotropic Glutamate Receptor Agonist in Rats

10.1126/science.281.5381.1349 ◽

1998 ◽

Vol 281 (5381) ◽

pp. 1349-1352 ◽

Cited By ~ 715

Author(s):

B. Moghaddam

Keyword(s):

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Metabotropic Glutamate ◽

Group Ii ◽

Glutamate Receptor Agonist

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Protection of neonatal rat brain from hypoxicischemic injury by LY379268, a Group II metabotropic glutamate receptor agonist

Neuroreport ◽

10.1097/00001756-199912160-00037 ◽

1999 ◽

Vol 10 (18) ◽

pp. 3927-3931 ◽

Cited By ~ 33

Author(s):

Zhengwei Cai ◽

Feng Xiao ◽

Jonathan D. Fratkin ◽

Philip G. Rhodes

Keyword(s):

Rat Brain ◽

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Neonatal Rat ◽

Metabotropic Glutamate ◽

Group Ii ◽

Glutamate Receptor Agonist ◽

Neonatal Rat Brain

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Modulation of Amphetamine-Induced Dopamine Release by Group II Metabotropic Glutamate Receptor Agonist LY354740 in Non-Human Primates Studied with Positron Emission Tomography

Neuropsychopharmacology ◽

10.1038/sj.npp.1300902 ◽

2005 ◽

Vol 31 (5) ◽

pp. 967-977 ◽

Cited By ~ 31

Author(s):

Bart N M van Berckel ◽

Lawrence S Kegeles ◽

Rikki Waterhouse ◽

Ningning Guo ◽

Dah-Ren Hwang ◽

...

Keyword(s):

Positron Emission Tomography ◽

Glutamate Receptor ◽

Receptor Agonist ◽

Dopamine Release ◽

Metabotropic Glutamate Receptor ◽

Emission Tomography ◽

Metabotropic Glutamate ◽

Positron Emission ◽

Group Ii ◽

Glutamate Receptor Agonist

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The Preclinical Properties of a Novel Group II Metabotropic Glutamate Receptor Agonist LY379268

CNS Drug Reviews ◽

10.1111/j.1527-3458.2007.00024.x ◽

2007 ◽

Vol 0 (0) ◽

pp. 071115144033001-??? ◽

Cited By ~ 6

Author(s):

Gabor Imre

Keyword(s):

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Metabotropic Glutamate ◽

Group Ii ◽

Glutamate Receptor Agonist

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Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate

Experimental Neurology ◽

10.1016/j.expneurol.2004.12.019 ◽

2005 ◽

Vol 192 (2) ◽

pp. 420-436 ◽

Cited By ~ 34

Author(s):

Jaroslava Folbergrová ◽

Rastislav Druga ◽

Jakub Otáhal ◽

Renata Haugvicová ◽

Pavel Mareš ◽

...

Keyword(s):

Brain Damage ◽

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Homocysteic Acid ◽

Metabotropic Glutamate ◽

Immature Rats ◽

Group Ii ◽

Glutamate Receptor Agonist

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METABOLISM AND DISPOSITION OF A POTENT GROUP II METABOTROPIC GLUTAMATE RECEPTOR AGONIST, IN RATS, DOGS, AND MONKEYS

Drug Metabolism and Disposition ◽

10.1124/dmd.105.004978 ◽

2005 ◽

Vol 33 (9) ◽

pp. 1373-1381 ◽

Cited By ~ 5

Author(s):

Joyce K. James ◽

Masato Nakamura ◽

Atsuro Nakazato ◽

Kanyin E. Zhang ◽

Merryl Cramer ◽

...

Keyword(s):

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Metabotropic Glutamate ◽

Group Ii ◽

Glutamate Receptor Agonist

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Pharmacological in vivo studies with LY 354740, a selective, group II metabotropic glutamate receptor agonist

European Neuropsychopharmacology ◽

10.1016/s0924-977x(98)90139-0 ◽

1998 ◽

Vol 8 ◽

pp. S43

Keyword(s):

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

In Vivo Studies ◽

Metabotropic Glutamate ◽

Group Ii ◽

Glutamate Receptor Agonist

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Effects of the group II metabotropic glutamate receptor agonist, LY354740 on schedule-controlled behaviour in rats

Behavioural Pharmacology ◽

10.1097/00008877-199905000-00008 ◽

1999 ◽

Vol 10 (3) ◽

pp. 319-325 ◽

Cited By ~ 10

Author(s):

N. A. Moore ◽

G. Rees ◽

J. A. Monn

Keyword(s):

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Metabotropic Glutamate ◽

Group Ii ◽

Glutamate Receptor Agonist

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