scholarly journals CORR Insights®: What is the Relative Effectiveness of the Various Surgical Treatment Options for Distal Radius Fractures? A Systematic Review and Network Meta-analysis of Randomized Controlled Trials

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Ryan P. Calfee
2021 ◽  
pp. 219256822110653
Author(s):  
Gustav Ø. Andersen ◽  
Stefan Milosevic ◽  
Mads M. Jensen ◽  
Mikkel Ø. Andersen ◽  
Ane Simony ◽  
...  

Study design Systematic Review Objective To evaluate the efficacy of available treatment options for patients with persistent coccydynia through a systematic review. Methods Original peer-reviewed publications on treatment for coccydynia were identified using Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines by performing a literature search of relevant databases, from their inception to January 17, 2020, combined with other sources. Data on extracted treatment outcome was pooled based on treatment categories to allow for meta-analysis. All outcomes relevant to the treatment efficacy of coccydynia were extracted. No single measure of outcome was consistently present among the included studies. Numeric Rating Scale, (NRS, 0–10) for pain was used as the primary outcome measure. Studies with treatment outcome on adult patients with chronic primary coccydynia were considered eligible. Results A total of 1980 patients across 64 studies were identified: five randomized controlled trials, one experimental study, one quasi-experimental study, 11 prospective observational studies, 45 retrospective studies and unpublished data from the DaneSpine registry. The greatest improvement in pain was achieved by patients who underwent radiofrequency therapy (RFT, mean Visual Analog Scale (VAS) decreased by 5.11 cm). A similar mean improvement was achieved from Extracorporeal Shockwave Therapy (ESWT, 5.06), Coccygectomy (4.86) and Injection (4.22). Although improved, the mean change was less for those who received Ganglion block (2.98), Stretching/Manipulation (2.19) and Conservative/Usual Care (1.69). Conclusion This study highlights the progressive nature of treatment for coccydynia, starting with noninvasive methods before considering coccygectomy. Non-surgical management provides pain relief for many patients. Coccygectomy is by far the most thoroughly investigated treatment option and may be beneficial for refractory cases. Future randomized controlled trials should be conducted with an aim to compare the efficacy of interventional therapies amongst each other and to coccygectomy.


2020 ◽  
Author(s):  
Fabrizio Brindisino ◽  
Mattia Salomon ◽  
Silvia Giagio ◽  
Chiara Pastore ◽  
Tiziano Innocenti

Shoulder pain (SP) is one of the most common musculoskeletal complaints 1 and it can negatively affect the correct movement of the upper limb, night rest, daily life activity, work and sports performances and autonomy 2-4. Rotator cuff (RC) disease represents the most common cause of SP and it is responsible for up to 70% of all shoulder related visits to clinicians 5. RC tears are generally considered to be a normal imaging result and a age related disorder 6, when we consider patients over 5th decade. Infact, RC tears are present between 20% to 54% of subjects aged between 60 and 80 years 7; moreover full-thickness RC tears can be evident in approximately 20% of patients over 65 years old 8. RC tears have been widely studied and a lot of management strategies of patients with RC tears are actually available in literature 9,10; even if successful results have been achieved for both conservative and surgical treatment of RC tears, optimal management and best choice treatments for patient with RC tears are still unknown and debated 11,12. Generally, conservative treatments were often administered in partial thickness RC tear, while surgery was judged as better option for massive tear 13. Furthermore, conservative treatment has often been advocated for older patients with comorbidities, while surgery is suggested for younger people 14,15. Lastly, physiotherapy did not reach structural healing of the tear, however successful rate was reported also after conservative treatment of massive tears: nevertheless, some concerns persist about the enlargement of the anatomical lesion and following loss of strength and pain persistence 7. In the USA, in 2006, the annual incidence of surgery for RC tear was 98 procedures per 100,000 inhabitants and the incidence was increased form the application of the arthroscopic strategies 16,17, moreover, despite being considered as a successful treatment option, surgical treatment is estimated to cause from 20 to 90% rate of re-tear after surgery 18,19. In such a framework of uncertainty on optimal management, several randomized controlled trials (RCTs) have been structured to compare the efficacy of surgical and conservative treatments for patient with any type of RC tears; results coming from different studies are often contradictory and substantially influenced by the recruited sample characteristics. The aim of this systematic review is to analyze the results of randomized controlled trials which compare surgical and conservative treatments for patient with any type of RC tear through meta-analysis. Furthermore, this study also aims to know which are the most common indication to surgery: authors would like to understand if the presence of structural failure at the imaging assessment, the presence of pain refractory to conservative treatment, the presence of strength deficit or the combination of this mentioned elements are considered as decision criteria for choosing a surgery approach.


2020 ◽  
Author(s):  
Yu Zhang ◽  
Xudong Jiang ◽  
Zhijie Wang ◽  
Mingming He ◽  
Zimeng Lv ◽  
...  

Abstract Background: Persistent and intractable hiccups are a common clinical symptom that cause considerable physical pain to patients and severely damage their quality of lives. An increasing number of studies have demonstrated that acupuncture applied at acupoints dominated by Cuanzhu (BL2) can be used as one of the nonpharmacological therapies for controlling intractable hiccups. However, there is insufficient evidence evaluating the safety and effectiveness of those interventions. Therefore, this study is intended to conduct a systematic review and meta-analysis to provide evidence for a further study investigating alternative treatment options for persistent and intractable hiccups.Methods: Randomized controlled trials (RCTs) of adult patients aged >18 years who meet the criteria for intractable hiccup diagnosis will be included, regardless of gender, nationality, and education level. Eight electronic databases will be searched, including four Chinese databases (CNKI, SinoMed, Wanfang Database, and Chinese Scientific Journal Database), four English databases (Web of Science, Medline, Embase, and Cochrane Library), from their date of establishment to September 2020. Two independent reviewers will evaluate the title summary for each RCT. Disagreements will be discussed with a third commentator. Data integration, heterogeneity analysis, subgroup analysis, and sensitivity analysis, will be performed using R-3.3.2 software. The RevMan 5.3 software will be used for the meta-analysis, and the “risk of bias” assessment will be conducted based on the methodological quality of the included trials recommended by the Cochrane Handbook 5.1. The quality evaluation of this study will be completed by the Grading of Recommendations, Assessment, Development, and Evaluation.Discusstion: This systematic review will provide evidence to assess the validity and safety of applying acupuncture at acupoints dominated by Cuanzhu (BL2) for persistent and intractable hiccups, which may provide clinicians with more choices in the treatment of this disease.Systematic review registration: PROSPERO CRD42020114900


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