Use of PD-1 Inhibitors in the Treatment of Advanced Basal Cell Carcinoma

Faculty Opinions recommendation of An Investigator-Initiated Open-Label Trial of Sonidegib in Advanced Basal Cell Carcinoma Patients Resistant to Vismodegib.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725919181.793539336 ◽

2017 ◽

Author(s):

David Leffell

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Open Label ◽

Open Label Trial ◽

Efficacy of sonidegib in histologic subtypes of advanced basal cell carcinoma: Results from the final analysis of the randomized phase 2 Basal Cell Carcinoma Outcomes With LDE225 Treatment (BOLT) trial at 42 months

10.1016/j.jaad.2020.08.042 ◽

2020 ◽

Author(s):

Reinhard Dummer ◽

John T. Lear ◽

Alex Guminski ◽

Liang Joo Leow ◽

Nicholas Squittieri ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Final Analysis ◽

Phase 2 ◽

Histologic Subtypes ◽

Randomized Phase 2 ◽

Neoadjuvant Vismodegib followed by radiation in locally advanced basal cell carcinoma

Current Problems in Cancer ◽

10.1016/j.currproblcancer.2021.100736 ◽

2021 ◽

pp. 100736

Author(s):

Diya M Sabu ◽

Jeska Kroes ◽

Charles Gilham ◽

Ann Fleming ◽

Fergal C Kelleher

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Time to tumor response and planned subgroup analyses from the BOLT trial for sonidegib in advanced basal cell carcinoma

10.1016/j.jaad.2018.05.1172 ◽

2018 ◽

Vol 79 (3) ◽

pp. AB297

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Tumor Response ◽

Subgroup Analyses ◽

LBA47 Primary analysis of phase II results for cemiplimab in patients (pts) with locally advanced basal cell carcinoma (laBCC) who progress on or are intolerant to hedgehog inhibitors (HHIs)

Annals of Oncology ◽

10.1016/j.annonc.2020.08.2277 ◽

2020 ◽

Vol 31 ◽

pp. S1175-S1176 ◽

Cited By ~ 1

Author(s):

A.J. Stratigos ◽

A. Sekulic ◽

K. Peris ◽

O. Bechter ◽

C. Dutriaux ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Phase Ii ◽

Basal Cell ◽

Locally Advanced ◽

Primary Analysis ◽

Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma

New England Journal of Medicine ◽

10.1056/nejmoa0905360 ◽

2009 ◽

Vol 361 (12) ◽

pp. 1164-1172 ◽

Cited By ~ 793

Author(s):

Daniel D. Von Hoff ◽

Patricia M. LoRusso ◽

Charles M. Rudin ◽

Josina C. Reddy ◽

Robert L. Yauch ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Hedgehog Pathway ◽

26200 Tumor burden in patients with locally advanced basal cell carcinoma and metastatic basal cell carcinoma following treatment with sonidegib: Results of the 42-month BOLT study

10.1016/j.jaad.2021.06.377 ◽

2021 ◽

Vol 85 (3) ◽

pp. AB89

Author(s):

Michael Migden ◽

Aaron S. Farberg ◽

James Spencer ◽

Felix Kiecker ◽

Alexander Guminski ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Tumor Burden ◽

Metastatic Basal Cell Carcinoma ◽

26202 Antineoplastic therapy after discontinuation of sonidegib 200 mg in patients with advanced basal cell carcinoma: Results from the 42-month, randomized, double-blind BOLT study

10.1016/j.jaad.2021.06.378 ◽

2021 ◽

Vol 85 (3) ◽

pp. AB89

Author(s):

Ralf Gutzmer ◽

Alexander Guminski ◽

Peter Foley ◽

Anne Lynn S. Chang ◽

Karl Lewis ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Antineoplastic Therapy ◽

Basal Cell ◽

Double Blind ◽

16306 Effect of concomitant medications on efficacy of sonidegib 200 mg daily in patients with locally advanced basal cell carcinoma: Results of the 42-month randomized, double-blind BOLT study

10.1016/j.jaad.2020.06.324 ◽

2020 ◽

Vol 83 (6) ◽

pp. AB59

Author(s):

Reinhard Dummer ◽

Michael R. Migden ◽

Nicholas A. Squittieri ◽

Li Liu ◽

Alexander Guminski ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽

Double Blind ◽

Concomitant Medications ◽

Xanthomatous Dermal Changes in a Patient With Locally Advanced Basal Cell Carcinoma Treated Using Vismodegib

American Journal of Dermatopathology ◽

10.1097/dad.0000000000001849 ◽

2021 ◽

Vol Publish Ahead of Print ◽

Author(s):

Shane D. B. Smith ◽

Callisia N. Clarke ◽

Melanie A. Clark ◽

Amy K. Harker-Murray ◽

Olayemi Sokumbi

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Locally Advanced ◽