White-coat hypertension/effect is associated with higher arterial stiffness and stroke events

2022 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Alec Saunders ◽  
Gani N. Nuredini ◽  
Frances A. Kirkham ◽  
Erin Drazich ◽  
Eva Bunting ◽  
...  
2020 ◽  
Vol 25 (Supplement 1) ◽  
pp. S156
Author(s):  
Fran Kirkham ◽  
A Saunders ◽  
GN Nuredini ◽  
E Drazich ◽  
Philip Rankin ◽  
...  

2021 ◽  
Vol 39 (Supplement 1) ◽  
pp. e313
Author(s):  
Christina Antza ◽  
Polychronis Vazakidis ◽  
Ioannis Doundoulakis ◽  
Stella Stabouli ◽  
Vasilios Kotsis

2019 ◽  
Vol 37 ◽  
pp. e147-e148
Author(s):  
A. Saunders ◽  
G.N. Nuredini ◽  
E. Drazich ◽  
F.A. Kirkham ◽  
E. Bunting ◽  
...  

2007 ◽  
Vol 1 (2) ◽  
pp. 69
Author(s):  
S.-M. Kyvelou ◽  
C. Vlachopoulos ◽  
G. Vyssoulis ◽  
P. Pietri ◽  
P. Spanos ◽  
...  

2016 ◽  
Vol 94 (1) ◽  
pp. 112-116 ◽  
Author(s):  
Michal Mestanik ◽  
Alexander Jurko ◽  
Andrea Mestanikova ◽  
Tomas Jurko ◽  
Ingrid Tonhajzerova

Elevated blood pressure (BP) is a major risk factor for atherosclerosis. As the studies concerning vascular alterations in pediatric patients are rare, we aimed to study the relationship between hypertension and arterial stiffness in adolescence by novel method independent from BP during examination. Twenty nonobese adolescent boys (16.5 ± 0.4 years) with newly diagnosed essential hypertension, 20 adolescent boys (16.7 ± 0.4 years) with newly diagnosed white-coat hypertension, and 20 healthy controls matched to age and body mass index were examined. Cardio-ankle vascular index (CAVI), brachial-ankle pulse wave velocity (baPWV), pre-ejection period (PEP), and ejection time (ET) were evaluated. CAVI was significantly increased in essential hypertension patients compared with controls (p < 0.05) with no significant difference in white-coat hypertension patients. Significantly higher baPWV was found in essential and white-coat hypertension patients compared with controls (both p < 0.001). White-coat hypertension patients showed significantly shortened PEP and ET compared with controls (p < 0.01 and p < 0.001, respectively) and essential hypertension patients (both p < 0.05). For the first time, the arterial stiffness in adolescents with newly diagnosed essential and white-coat hypertension was studied using BP-independent index CAVI combined with conventional baPWV. Our study revealed significantly increased CAVI in adolescents with newly diagnosed essential hypertension compared with controls. Our findings could help to understand hypertension–atherosclerosis interaction.


Hypertension ◽  
2016 ◽  
Vol 68 (suppl_1) ◽  
Author(s):  
Sikarin Upala ◽  
Anawin Sanguankeo

Background: Previous studies have shown inconclusive effects of target organ damage from white-coat hypertension (WCHT). Arterial stiffness is involved in the atherosclerotic processes in the setting of sustained hypertension. This meta-analysis aimed to compare arterial stiffness in subjects with diagnosis of WCHT to subjects with normotension (NT) and SHT. Methods: A comprehensive search of the databases of the MEDLINE and EMBASE was performed from inception through May 2016. The inclusion criterion was the observational studies’ assessment of the association between WCHT and NT or SHT in adult subjects. European Society of Hypertension practice guidelines for ambulatory blood pressure (BP) monitoring was used to define WCHT (office BP≥140/90mmHg and daytime BP <135/85mmHg), and SHT (office BP≥140/90mmHg and daytime BP≥135/85mmHg). Aortic stiffness was assessed using Carotid-femoral pulse wave velocity (PWV) measurements. Pooled mean difference (MD) of PWV and 95% confidence interval (CI) were calculated using a random-effect, generic inverse variance method. Results: Data were extracted from 4 observational studies involving 2,413 subjects. PWV is not different in patients with WCHT compared with SHT (pooled MD= -0.25 m/sec; 95% CI, -0.81 to 0.30; P-value=0.37, I 2 =74%). PWV in WCHT is also not different when compared with PWV in NT (MD= 0.86 m/sec; 95% CI, -0.30 to 2.03; P-value=0.15, I 2 =97%). Conclusion: In a meta-analysis, we observe that arterial stiffness measured by pulse wave velocity is not different in patients with white-coat hypertension when compared with sustained hypertension or normotension.


2011 ◽  
Vol 16 (5) ◽  
pp. 218-223 ◽  
Author(s):  
Ioannis Andrikou ◽  
Costas Tsioufis ◽  
Kyriakos Dimitriadis ◽  
Dimitris Syrseloudis ◽  
Panagiota Valenti ◽  
...  

Medicine ◽  
2018 ◽  
Vol 97 (42) ◽  
pp. e12888 ◽  
Author(s):  
Peng Cai ◽  
Yan Peng ◽  
Yan Wang ◽  
Xukai Wang

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