Progressive Decrease of Peripapillary Angioflow Vessel Density During Structural and Visual Field Progression in Early Primary Open-angle Glaucoma

2017 ◽  
Vol 26 (7) ◽  
pp. 661-664 ◽  
Author(s):  
Gábor Holló
Keyword(s):  
Visual Field ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Vessel Density ◽  
Open Angle ◽  
Progressive Decrease ◽  
Visual Field Progression ◽  
Early Primary

scholarly journals A Small Disc Area Is a Risk Factor for Visual Field Loss Progression in Primary Open-Angle Glaucoma: The Glaucoma Stereo Analysis Study

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Yasushi Kitaoka ◽  
Masaki Tanito ◽  
Yu Yokoyama ◽  
Koji Nitta ◽  
Maki Katai ◽  
...  
Keyword(s):  
Visual Field ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Visual Field Loss ◽  
Morphological Parameters ◽  
Open Angle ◽  
Analysis Study ◽  
Visual Field Progression ◽  
Stereo Analysis ◽  
Disc Area

Purpose. The Glaucoma Stereo Analysis Study, a cross-sectional multicenter collaborative study, used a stereo fundus camera (nonmyd WX) to assess various morphological parameters of the optic nerve head (ONH) in glaucoma patients. We compared the associations of each parameter between the visual field loss progression group and no-progression group. Methods. The study included 187 eyes of 187 patients with primary open-angle glaucoma or normal-tension glaucoma. We divided the mean deviation (MD) slope values of all patients into the progression group (<−0.3 dB/year) and no-progression group (≧−0.3 dB/year). ONH morphological parameters were calculated with prototype analysis software. The correlations between glaucomatous visual field progression and patient characteristics or each ONH parameter were analyzed with Spearman’s rank correlation coefficient. Results. The MD slope averages in the progression group and no-progression group were −0.58 ± 0.28 dB/year and 0.05 ± 0.26 dB/year, respectively. Among disc parameters, vertical disc width (diameter), disc area, cup area, and cup volume in the progression group were significantly less than those in the no-progression group. Logistic regression analysis revealed a significant association between the visual field progression and disc area (odds ratio 0.49/mm2 disc area). Conclusion. A smaller disc area may be associated with more rapid glaucomatous visual field progression.

scholarly journals Comparison of visual field progression in new-diagnosed primary open-angle and exfoliation glaucoma patients in Sweden.

2020 ◽  
Author(s):  
Marcelo Ayala
Keyword(s):  
Visual Field ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
T Test ◽  
Open Angle ◽  
Visual Field Progression ◽  
Exfoliation Glaucoma ◽  
The Difference ◽  
Glaucoma Group

Abstract Background: The present study aimed to compare visual field progression in new-diagnosed exfoliation versus open-angle glaucoma patients. Methods: Retrospective study. The study included patients with new-diagnosed primary open-angle and exfoliation glaucoma. All patients were followed for three years with reliable visual fields. At least five reliable fields were needed for inclusion. Exfoliation and open-angle glaucoma were defined based on the European Glaucoma Society guidelines. Visual field evaluation was performed using the software threshold 24-2 of the Humphrey Field Analysis. Outcomes: Visual field progression. For visual field progression, three different strategies were used: mean deviation (MD), visual field index (VFI), and the guided progression analysis (GPA). Results: The study included 128 subjects, of the 54 in the open-angle and 74 in the exfoliation glaucoma group. The MD difference values were higher in the exfoliation (-3.17 dB) than in the primary open-angle (-1.25 dB) glaucoma group in the three-year follow-up period. The difference between groups was significant (t-test, p=<0.001). The difference in VFI was calculated for the three years follow-up period. The difference was higher in the exfoliation (-7.65%) than in the primary open (-1.90%) glaucoma group (t-test, p=<0.001). The GPA showed progression in 58% of cases in exfoliation, and 13% in primary open glaucoma group (Chi-square, p=<0.001). Conclusion: The present study found a more frequent and faster visual field progression in exfoliation than in primary open-angle glaucoma patients. New-diagnosed exfoliation glaucoma patients must be controlled and treated more strictly than primary open-angle glaucoma patients to avoid visual field deterioration.

scholarly journals Peripapillary and Macular Vessel Density in Patients with Primary Open-Angle Glaucoma and Unilateral Visual Field Loss

Ophthalmology ◽  
2018 ◽  
Vol 125 (4) ◽  
pp. 578-587 ◽  
Author(s):  
Adeleh Yarmohammadi ◽  
Linda M. Zangwill ◽  
Patricia Isabel C. Manalastas ◽  
Nathanael J. Fuller ◽  
Alberto Diniz-Filho ◽  
...  
Keyword(s):  
Visual Field ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Visual Field Loss ◽  
Vessel Density ◽  
Open Angle

scholarly journals Early Primary Open-Angle Glaucoma

2018 ◽  
Vol 80 (4) ◽  
pp. 25-31
Author(s):  
Austin R. Lifferth
Keyword(s):  
Visual Field ◽  
Primary Open Angle Glaucoma ◽  
Population Studies ◽  
Open Angle Glaucoma ◽  
Visual Field Defects ◽  
Open Angle ◽  
Fiber Layer ◽  
Advanced Stages ◽  
Early Primary ◽  
Field Defects

Glaucoma is the leading cause of irreversible blindness worldwide and is projected to affect more than 79.6 million people by 2020, over 10% of whom will be bilaterally blind.1 This multifactorial progressive optic neuropathy causes characteristic retinal nerve fiber layer damage that will eventually lead to associated glaucomatous visual field defects if left untreated. Unfortunately, these visual field defects are difficult for the patient to detect until more advanced stages and, as a result, early glaucoma is usually asymptomatic.2 This paper presents a case that is consistent with population studies that suggest that as many as half of people with glaucoma are unaware that they have the disease.3

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