Changes in Disparities in Estimated HIV Incidence Rates Among Black, Hispanic/Latino, and White Men Who Have Sex With Men (MSM) in the United States, 2010–2015

2019 ◽  
Vol 81 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Donna Hubbard McCree ◽  
Austin M. Williams ◽  
Harrell W. Chesson ◽  
Linda Beer ◽  
William L. Jeffries ◽  
...  
Keyword(s):  
United States ◽  
White Men ◽  
The United States ◽  
Incidence Rates ◽  
Hiv Incidence ◽  
Sex With Men

scholarly journals Addressing Gaps in HIV Preexposure Prophylaxis Care to Reduce Racial Disparities in HIV Incidence in the United States

2018 ◽  
Author(s):  
Samuel M. Jenness ◽  
Kevin M. Maloney ◽  
Dawn K. Smith ◽  
Karen W. Hoover ◽  
Steven M. Goodreau ◽  
...  
Keyword(s):  
United States ◽  
Racial Disparities ◽  
Hiv Transmission ◽  
White Men ◽  
The United States ◽  
Hiv Incidence ◽  
Black And White ◽  
Empirical Estimates ◽  
Preexposure Prophylaxis ◽  
Sex With Men

ABSTRACTThe potential for HIV preexposure prophylaxis (PrEP) to reduce the racial disparities in HIV incidence in the United States may be limited by racial gaps in PrEP care. We used a network-based mathematical model of HIV transmission for younger black and white men who have sex with men (B/WMSM) in the Atlanta area to evaluate how race-stratified transitions through the PrEP care continuum from initiation to adherence and retention could impact HIV incidence overall and disparities in incidence between races, using current empirical estimates of BMSM continuum parameters. Relative to a no-PrEP scenario, implementing PrEP according to observed BMSM parameters was projected to yield a 23% decline in HIV incidence (HR = 0.77) among BMSM at year 10. The racial disparity in incidence in this observed scenario was 4.95 per 100 person-years at risk (PYAR), a 19% decline from the 6.08 per 100 PYAR disparity in the no-PrEP scenario. If BMSM parameters were increased to WMSM values, incidence would decline by 47% (HR = 0.53), with an associated disparity of 3.30 per 100 PYAR (a 46% decline in the disparity). PrEP could simultaneously lower HIV incidence overall and reduce racial disparities despite current gaps in PrEP care. Interventions addressing these gaps will be needed to substantially decrease disparities.

Incidence of testicular cancer in the United States from 1992 to 2009.

2013 ◽  
Vol 31 (6_suppl) ◽  
pp. 339-339 ◽  
Author(s):  
Manas Nigam ◽  
Brisa Aschebrook-Kilfoy ◽  
Sergey Shikanov ◽  
Scott E. Eggener
Keyword(s):  
United States ◽  
Testicular Cancer ◽  
White Men ◽  
The United States ◽  
Incidence Rates ◽  
The Us ◽  
Hispanic Men ◽  
Tumor Characteristic ◽  
Race Ethnicity ◽  
Hispanic White

339 Background: The incidence of testicular cancer (TC) increased in the US through 2003. However, little is known about these trends after 2003. We sought to determine trends in TC incidence based on race, ethnicity and tumor characteristics. Methods: TC incidence and tumor characteristic data from 1992-2009 were extracted from the Surveillance, Epidemiology, and End Results-13 (SEER) registry. Trends were determined using JoinPoint. Results: TC incidence in the US increased from 1992 (5.7/100,000) to 2009 (6.8/100,000) with annual percentage change (APC) of 1.1% (p < 0.001). TC rates were highest in non-Hispanic white men (1992: 7.5/100,000; 2009: 8.6/1000) followed by Hispanic men (1992: 4.0/100,000; 2009: 6.3/100,000) and lowest among non-Hispanic black men (1992: 0.7/100,000; 2009: 1.7/100,000). Significantly increasing incidence rates were observed in non-Hispanic white men (1.2%, p < 0.001) but most prominently among Hispanics, especially from 2002-2009 (5.6%, p < 0.01). A significant increase was observed for localized TC (1.21%, p < 0.001) and metastatic TC (1.43%, p < 0.01). Increased incidence occurred in localized tumors for non-Hispanic white men (1.56%, p <0.001), while Hispanic men experienced an increase in localized (2.6%, p < 0.001), regionalized (16.5% from 2002-09, p < 0.01), and distant (2.6%, p < 0.01) disease. Conclusions: Through 2009, testicular cancer incidence continues to increase in the United States, most notably among Hispanic men. [Table: see text]

scholarly journals Running Backwards: Consequences of Current HIV Incidence Rates for the Next Generation of Black MSM in the United States

2015 ◽  
Vol 20 (1) ◽  
pp. 7-16 ◽  
Author(s):  
Derrick D. Matthews ◽  
◽  
A. L. Herrick ◽  
Robert W. S. Coulter ◽  
M. Reuel Friedman ◽  
...  
Keyword(s):  
United States ◽  
The United States ◽  
Incidence Rates ◽  
Black Msm ◽  
Hiv Incidence ◽  
Next Generation

Incidence of Testicular Cancer in the United States, 1999-2004

2009 ◽  
Vol 4 (4) ◽  
pp. 353-360 ◽  
Author(s):  
Julie S. Townsend ◽  
Lisa C. Richardson ◽  
Robert R. German
Keyword(s):  
United States ◽  
Testicular Cancer ◽  
Alaska Native ◽  
Germ Cell Tumors ◽  
White Men ◽  
The United States ◽  
Incidence Rates ◽  
Testicular Germ Cell ◽  
Cancer Statistics ◽  
Hispanic White

Testicular cancer is rare but primarily affects young men. To characterize the current incidence of testicular cancer in the United States, U.S. Cancer Statistics data from 1999 through 2004 were examined. Age-adjusted (2000 U.S. standard) incidence rates were calculated for seminoma and nonseminoma testicular germ cell tumors (TGCTs). Hispanic men had the largest increase in incidence rates for nonseminomas, followed by non-Hispanic White men (annual percentage change of 3.2% and 1.9%, respectively, p < .05). Nonseminomas peaked at a younger age for Hispanic, American Indian/Alaska Native (AIAN), and Asian/Pacific Islander (API) men. Whereas 9.6% of TGCTs were diagnosed at a distant stage in non-Hispanic White men, more Hispanic (16.1%), Black (13.8%), AIAN (16.8%), and API (14.9%) men with TGCTs were diagnosed with distant stage. Monitoring incidence rates for rare cancers by race/ethnicity has improved with national population-based cancer registry coverage. Disparities in diagnosis stage have implications for effective treatment of TGCTs.

Increasing Incidence of Testicular Germ Cell Tumors Among Black Men in the United States

2005 ◽  
Vol 23 (24) ◽  
pp. 5757-5761 ◽  
Author(s):  
Katherine A. McGlynn ◽  
Susan S. Devesa ◽  
Barry I. Graubard ◽  
Philip E. Castle
Keyword(s):  
United States ◽  
Germ Cell ◽  
Black Men ◽  
Germ Cell Tumors ◽  
White Men ◽  
The United States ◽  
Incidence Rates ◽  
Seer Program ◽  
Testicular Germ Cell Tumors ◽  
Testicular Germ Cell

Purpose There has been marked disparity in the incidence of testicular germ cell tumors (TGCT) among white and black men for a number of decades in the United States. Since at least the beginning of the Surveillance, Epidemiology, and End Results (SEER) Program in 1973, incidence rates among white men have been five times higher than rates among black men. In addition, rates among white men have been increasing, whereas rates among black men have remained stable. However, a recent examination of ethnic-specific rates suggested that the incidence among black men may have begun to change in the 1990s. Patients and Methods TGCT incidence data from nine registries of the SEER Program were analyzed for the years 1973 to 2001. Trends were examined separately for seminoma and nonseminoma. Results Analyses found that the incidence of TGCT began to increase among black men between the 1988 to 1992 and 1993 to 1997 periods. Before that time, incidence among black men had decreased by 14.8%. Between 1988 to 1992 and 1998 to 2001, however, the incidence increased by 100%, with the incidence of seminoma increasing twice as much (124.4%) as the incidence of nonseminoma (64.3%). Over the 29-year time period, there was no evidence of a change in the proportion of tumors diagnosed at earlier stages among black men. In contrast, the proportion of tumors diagnosed at localized stages significantly increased among white men. Conclusion The incidence of TGCT among black men has increased since 1988 to 1992. Although the reasons for this increase are unclear, screening and earlier diagnosis of TGCT do not seem to be factors.

scholarly journals Running in Place: Implications of HIV Incidence Estimates among Urban Men Who Have Sex with Men in the United States and Other Industrialized Countries

2009 ◽  
Vol 13 (4) ◽  
pp. 615-629 ◽  
Author(s):  
Ron Stall ◽  
Luis Duran ◽  
Stephen R. Wisniewski ◽  
Mark S. Friedman ◽  
Michael P. Marshal ◽  
...  
Keyword(s):  
United States ◽  
The United States ◽  
Hiv Incidence ◽  
Industrialized Countries ◽  
Urban Men ◽  
Sex With Men

scholarly journals The Role of Networks in Racial Disparities in HIV Incidence Among Men Who Have Sex with Men in the United States

2020 ◽  
Vol 24 (10) ◽  
pp. 2781-2796
Author(s):  
Stephen Bonett ◽  
Steven Meanley ◽  
Robin Stevens ◽  
Bridgette Brawner ◽  
José Bauermeister
Keyword(s):  
United States ◽  
Racial Disparities ◽  
The United States ◽  
Hiv Incidence ◽  
Sex With Men

Determinants of HIV Incidence Disparities Among Young and Older Men Who Have Sex with Men in the United States

2018 ◽  
Vol 22 (7) ◽  
pp. 2199-2213 ◽  
Author(s):  
William L. Jeffries ◽  
Kevin M. Greene ◽  
Gabriela Paz-Bailey ◽  
Donna Hubbard McCree ◽  
Lamont Scales ◽  
...  
Keyword(s):  
United States ◽  
Older Men ◽  
The United States ◽  
Hiv Incidence ◽  
Sex With Men

scholarly journals Predicted Effectiveness of Daily and Nondaily Preexposure Prophylaxis for Men Who Have Sex With Men Based on Sex and Pill-taking Patterns From the Human Immuno Virus Prevention Trials Network 067/ADAPT Study

2019 ◽  
Vol 71 (2) ◽  
pp. 249-255 ◽  
Author(s):  
Dobromir Dimitrov ◽  
James R Moore ◽  
Daniel Wood ◽  
Kate M Mitchell ◽  
Maoji Li ◽  
...  
Keyword(s):  
United States ◽  
Mathematical Model ◽  
New York ◽  
The United States ◽  
Hiv Incidence ◽  
Percentage Points ◽  
Preexposure Prophylaxis ◽  
Dosing Regimens ◽  
Prevention Trials ◽  
Sex With Men

Abstract Background The HIV Prevention Trials Network (HPTN) 067/Alternative Dosing to Augment PrEP Pill Taking (ADAPT) Study evaluated the feasibility of daily and nondaily human immunodeficiency virus (HIV) preexposure prophylaxis (PrEP) regimens among high-risk populations, including men who have sex with men (MSM) and transgender women, in Bangkok, Thailand and Harlem, New York. We used a mathematical model to predict the efficacy and effectiveness of different dosing regimens. Methods An individual-based mathematical model was used to simulate annual HIV incidence among MSM cohorts. PrEP efficacy for covered sex acts, as defined in the HPTN 067/ADAPT protocol, was estimated using subgroup efficacy estimates from the preexposure prophylaxis initiative (iPrEx) trial. Effectiveness was estimated by comparison of the HIV incidence with and without PrEP use. Results We estimated that PrEP was highly protective (85%–96% efficacy across regimens and sites) for fully covered acts. PrEP was more protective for partially covered acts in Bangkok (71%–88% efficacy) than in Harlem (62%–81% efficacy). Our model projects 80%, 62%, and 68% effectiveness of daily, time-driven, and event-driven PrEP for MSM in Harlem compared with 90%, 85%, and 79% for MSM in Bangkok. Halving the efficacy for partially covered acts decreases effectiveness by 8–9 percentage points in Harlem and by 5–9 percentage points in Bangkok across regimens. Conclusions Our analysis suggests that PrEP was more effective among MSM in Thailand than in the United States as a result of more fully covered sex acts and more pills taken around partially covered acts. Overall, nondaily PrEP was less effective than daily PrEP, especially in the United States where the sex act coverage associated with daily use was substantially higher.

scholarly journals Optimizing Human Immunodeficiency Virus Testing Interventions for Men Who Have Sex With Men in the United States: A Modeling Study

2015 ◽  
Vol 2 (4) ◽  
Author(s):  
Kevin P. Delaney ◽  
Eli S. Rosenberg ◽  
Michael R. Kramer ◽  
Lance A. Waller ◽  
Patrick S. Sullivan
Keyword(s):  
United States ◽  
Human Immunodeficiency Virus ◽  
Hiv Testing ◽  
Viral Suppression ◽  
The United States ◽  
Hiv Care ◽  
Hiv Incidence ◽  
Test Sensitivity ◽  
Immunodeficiency Virus ◽  
Sex With Men

Abstract Background.  In the United States, public health recommendations for men who have sex with men (MSM) include testing for human immunodeficiency virus (HIV) at least annually. We model the impact of different possible HIV testing policies on HIV incidence in a simulated population parameterized to represent US MSM. Methods.  We used exponential random graph models to explore, among MSM, the short-term impact on baseline (under current HIV testing practices and care linkage) HIV incidence of the following: (1) increasing frequency of testing; (2) increasing the proportion who ever test; (3) increasing test sensitivity; (4) increasing the proportion of the diagnosed population achieving viral suppression; and combinations of 1–4. We simulated each scenario 20 times and calculated the median and interquartile range of 3-year cumulative incidence of HIV infection. Results.  The only intervention that reduced HIV incidence on its own was increasing the proportion of the diagnosed population achieving viral suppression; increasing frequency of testing, the proportion that ever test or test sensitivity did not appreciably reduce estimated incidence. However, in an optimal scenario in which viral suppression improved to 100%, HIV incidence could be reduced by an additional 17% compared with baseline by increasing testing frequency to every 90 days and test sensitivity to 22 days postinfection. Conclusions.  Increased frequency, coverage, or sensitivity of HIV testing among MSM is unlikely to result in reduced HIV incidence unless men diagnosed through enhanced testing programs are also engaged in effective HIV care resulting in viral suppression at higher rates than currently observed.

Sign in / Sign up

Export Citation Format

Share Document