Role of Electroconvulsive Therapy in Managing Major Depressive Episodes in Patients With Dementia With Lewy Bodies

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Kate Fruitman ◽  
Dimitry Francois
Keyword(s):  
Electroconvulsive Therapy ◽  
Dementia With Lewy Bodies ◽  
Lewy Bodies ◽  
Major Depressive ◽  
Major Depressive Episodes ◽  
Depressive Episodes

scholarly journals Role of Translocator Protein Density, a Marker of Neuroinflammation, in the Brain During Major Depressive Episodes

2015 ◽  
Vol 72 (3) ◽  
pp. 268 ◽  
Author(s):  
Elaine Setiawan ◽  
Alan A. Wilson ◽  
Romina Mizrahi ◽  
Pablo M. Rusjan ◽  
Laura Miler ◽  
...  
Keyword(s):  
Translocator Protein ◽  
Major Depressive ◽  
Protein Density ◽  
Major Depressive Episodes ◽  
Depressive Episodes ◽  
The Brain

scholarly journals Adjunctive ketamine in electroconvulsive therapy: Updated systematic review and meta-analysis

2017 ◽  
Vol 210 (6) ◽  
pp. 403-407 ◽  
Author(s):  
Alexander McGirr ◽  
Marcelo T. Berlim ◽  
David J. Bond ◽  
Peter Y. Chan ◽  
Lakshmi N. Yatham ◽  
...  
Keyword(s):  
Systematic Review ◽  
Electroconvulsive Therapy ◽  
Therapeutic Agent ◽  
Meta Analysis ◽  
Cognitive Effects ◽  
Major Depressive ◽  
Random Effects Models ◽  
Randomised Controlled ◽  
Major Depressive Episodes ◽  
Depressive Episodes

BackgroundKetamine has emerged as a novel therapeutic agent for major depressive episodes, spurring interest in its potential to augment electroconvulsive therapy (ECT).AimsWe sought to update our preliminary systematic review and meta-analysis, focusing on randomised controlled trials (RCTs) involving an index course of ECT, and testing the hypothesis that lack of efficacy is due to barbiturate anaesthetic co-administration.MethodWe searched EMBASE, CENTRAL and Medline to identify RCTs examining the efficacy of ketamine during a course of ECT. Data were synthesised from ten trials (ketamine group n = 333, comparator group n = 269) using pooled random effects models.ResultsElectroconvulsive therapy with ketamine was not associated with greater improvements in depressive symptoms or higher rates of clinical response or remission, nor did it result in pro-cognitive effects. This held true when limiting analysis to trials without barbiturate anaesthetic co-administration. Increased rates of confusion were reported.ConclusionsOverall, our analyses do not support using ketamine over other induction agents in ECT.

Depressive symptoms, major depressive episodes and cognitive test performance—What is the role of physical activity?

2012 ◽  
Vol 67 (4) ◽  
pp. 265-273 ◽  
Author(s):  
Kaisla Joutsenniemi ◽  
Annamari Tuulio-Henriksson ◽  
Marko Elovainio ◽  
Tommi Härkänen ◽  
Päivi Sainio ◽  
...  
Keyword(s):  
Physical Activity ◽  
Depressive Symptoms ◽  
Test Performance ◽  
Cognitive Test ◽  
Major Depressive ◽  
Cognitive Test Performance ◽  
Major Depressive Episodes ◽  
Depressive Episodes

Dementia with Lewy bodies

2018 ◽  
pp. 11-21
Author(s):  
O. S. Levin ◽  
E. E. Vasenina ◽  
A. Sh. Chimagomedova ◽  
N. G. Dudchenko
Keyword(s):  
Parkinson’S Disease ◽  
Dementia With Lewy Bodies ◽  
Cholinesterase Inhibitors ◽  
Lewy Bodies ◽  
Diagnosis And Treatment ◽  
Modern Concept ◽  
Historical Aspect ◽  
Neurodegenerative Process ◽  
Icd 10

Te lecture presents modern concept of the symptoms, diagnosis and treatment of dementia with Lewy bodies (DLB), which accounts for about 10% of cases of dementia. Te nosological status of DLB and the problem of ratio of DLB and Parkinson’s disease which, apparently, represent two phenotypic variants of one neurodegenerative process («diseases with Lewy bodies») are considered in historical aspect. Approaches to the diagnosis and coding of DLB in accordance with ICD-10 are proposed. Te role of cholinesterase inhibitors, antipsychotics, levodopa, rasagiline and other drugs in the treatment of patients with DLB is аnalyzed.

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