scholarly journals Spread of the SARS-CoV-2 UK-variant in the South East of France: impact on COVID-19 patients’ age, comorbidity profiles and clinical presentation

2021 ◽  
Author(s):  
Johan Courjon ◽  
Julie Contenti ◽  
Elisa Demonchy ◽  
Jacques Levraut ◽  
Pascal Barbry ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Demographic Data ◽  
Clinical Signs ◽  
Clinical Severity ◽  
University Hospital ◽  
The South ◽  
Pcr Screening ◽  
The Uk ◽  
Turn Over ◽  
The University

AbstractObjectivesThe variant 20I/501Y.V1, associated to a higher risk of transmissibility, emerged in Nice city (South East of France, French Riviera) during January 2021. The pandemic has resumed late December 2020 in this aera. A high incidence rate together with a fast turn-over of the main circulating variants, provided us the opportunity to analyze modifications in clinical profile and outcome traits.MethodsObservational study in the University hospital of Nice from December 2020 to February 2021. We analyzed data of sequencing of SARS-CoV-2 from the sewage collector and PCR screening from all positive samples at the hospital. Then, we described the characteristics of all COVID-19 patients admitted in the emergency department (ED) (n=1247) and those hospitalized in the infectious diseases ward or ICU (n=232). Demographic data, clinical signs and severity were recorded by the NEWS-2, SAPS-2 and SOFA scores were recorded and analyzed.Resultsthe UK-variant was absent in the area in December, then increasingly spread in January representing 59% of the PCR screening performed mid-February. The rate of patients over 65 years admitted to the ED decreased from 63% to 50% (p=0.001). The mean age of hospitalized patients in the infectious diseases ward decreased from 70.7 to 59.2 (p<0.001) while the proportion of patients without comorbidity increased from 16% to 42% (p=0.007). Neither the NEWS-2 score nor the main signs of clinical severity have changed over time.ConclusionSpread of the UK-variant in the South East of France affects younger and healthier patients.

scholarly journals Spread of the SARS-CoV-2 UK-variant in the South East of France: impact on COVID-19 patients age, comorbidity profiles and clinical presentation

2021 ◽  
Author(s):  
Johan Courjon ◽  
Julie Contenti ◽  
Elisa Demonchy ◽  
Jacques Levraut ◽  
Pascal Barbry ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
University Hospital ◽  
The South ◽  
Pcr Screening ◽  
High Incidence ◽  
High Incidence Rate ◽  
The Uk ◽  
Turn Over ◽  
The University ◽  
French Riviera

Abstract Objectives: The variant 20I/501Y.V1, associated to a higher risk of transmissibility, emerged in Nice city (South East of France, French Riviera) during January 2021. The pandemic has resumed late December 2020 in this aera. A high incidence rate together with a fast turn-over of the main circulating variants, provided us the opportunity to analyze modifications in clinical profile and outcome traits. Methods: Observational study in the University hospital of Nice from December 2020 to February 2021. We analyzed data of sequencing of SARS-CoV-2 from the sewage collector and PCR screening from all positive samples at the hospital. Then, we described the characteristics of all COVID-19 patients admitted in the emergency department (ED) (n=1247) and those hospitalized in the infectious diseases ward or ICU (n=232). Results: the UK-variant was absent in this area in December, then increasingly spread in January representing 59% of the PCR screening performed mid-February. The rate of patients over 65 years admitted to the ED decreased from 63% to 50% (p=0.001). The mean age of hospitalized patients in the infectious diseases ward decreased from 70.7 to 59.2 (p<0.001) while the proportion of patients without comorbidity increased from 16% to 42% (p=0.007). Conclusion: Spread of the UK-variant in the South East of France affects younger and healthier patients.

scholarly journals COVID-19 patients age, comorbidity profiles and clinical presentation related to the SARS-CoV-2 UK-variant spread in the Southeast of France

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Johan Courjon ◽  
Julie Contenti ◽  
Elisa Demonchy ◽  
Jacques Levraut ◽  
Pascal Barbry ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
University Hospital ◽  
Pcr Screening ◽  
High Incidence ◽  
High Incidence Rate ◽  
The Mean ◽  
The Uk ◽  
Turn Over ◽  
The University ◽  
French Riviera

AbstractThe variant 20I/501Y.V1, associated to a higher risk of transmissibility, emerged in Nice city (Southeast of France, French Riviera) during January 2021. The pandemic has resumed late December 2020 in this area. A high incidence rate together with a fast turn-over of the main circulating variants, provided us the opportunity to analyze modifications in clinical profile and outcome traits. We performed an observational study in the University hospital of Nice from December 2020 to February 2021. We analyzed data of sequencing of SARS-CoV-2 from the sewage collector and PCR screening from all positive samples at the hospital. Then, we described the characteristics of all COVID-19 patients admitted in the emergency department (ED) (n = 1247) and those hospitalized in the infectious diseases ward or ICU (n = 232). The UK-variant was absent in this area in December, then increasingly spread in January representing 59% of the PCR screening performed mid-February. The rate of patients over 65 years admitted to the ED decreased from 63 to 50% (p = 0.001). The mean age of hospitalized patients in the infectious diseases ward decreased from 70.7 to 59.2 (p < 0.001) while the proportion of patients without comorbidity increased from 16 to 42% (p = 0.007). Spread of the UK-variant in the Southeast of France affects younger and healthier patients.

TETANUS OF THE NEWBORN INFANT

PEDIATRICS ◽  
1964 ◽  
Vol 34 (1) ◽  
pp. 32-37
Author(s):  
Dacio Pinheiro
Keyword(s):  
Public Health ◽  
Newborn Infant ◽  
Public Health Problem ◽  
Clinical Severity ◽  
University Hospital ◽  
Important Public Health Problem ◽  
Important Public Health ◽  
Pediatric Service ◽  
The Central Nervous System ◽  
The University

Tetanus in the newborn infant is still a most important public health problem in Brazil. An analysis of 238 cases, admitted in a two-year period to the pediatric service of the University Hospital in Sao Paulo, is presented. It is suggested that prognosis is related more closely to amount of tetanospasmin produced and absorbed by the central nervous system than to some of the more traditional indices of clinical severity. The plan of treatment in use is presented, since the over-all recovery rate compares very favorably with other published reports.

scholarly journals Drug safety profiles in geriatric patients with Parkinson’s disease using the FORTA (Fit fOR The Aged) classification: results from a mono-centric retrospective analysis

2020 ◽  
Author(s):  
S. Greten ◽  
J. I. Müller-Funogea ◽  
F. Wegner ◽  
G. U. Höglinger ◽  
N. Simon ◽  
...  
Keyword(s):  
Drug Safety ◽  
Geriatric Patients ◽  
Demographic Data ◽  
University Hospital ◽  
Potentially Inappropriate Medications ◽  
Hannover Medical School ◽  
The Common ◽  
The University ◽  
Geriatric Inpatients ◽  
Inappropriate Medications

AbstractTo reduce potentially inappropriate medications, the FORTA (Fit fOR The Aged) concept classifies drugs in terms of their suitability for geriatric patients with different labels, namely A (indispensable), B (beneficial), C (questionable), and D (avoid). The aims of our study were to assess the medication appropriateness in PD inpatients applying the FORTA list and drug-drug interaction software, further to assess the adequacy of FORTA list for patients with PD. We retrospectively collected demographic data, comorbidities, laboratory values, and the medication from the discharge letters of 123 geriatric inpatients with PD at the university hospital of Hannover Medical School. Patients suffered on average from 8.2 comorbidities. The majority of the medication was labeled A (60.6% of PD-specific and 40.9% of other medication) or B (22.3% of PD-specific and 26.9% of other medication). Administered drugs labeled with D were amantadine, clozapine, oxazepam, lorazepam, amitriptyline, and clonidine. Overall, 545 interactions were identified, thereof 11.9% severe interactions, and 1.7% contraindicated combinations. 81.3% of patients had at least one moderate or severe interaction. The FORTA list gives rational recommendations for PD-specific and other medication, especially for general practitioners. Considering the demographic characteristics and the common multimorbidity of geriatric PD patients, this study underlines the importance of awareness, education, and preventive interventions to increase drug safety.

scholarly journals Infectious diseases and the use of antibiotics in outpatients at the emergency department of the University Hospital of León, Nicaragua

2009 ◽  
Vol 13 (3) ◽  
pp. 349-354 ◽  
Author(s):  
C. den Engelsen ◽  
C. van der Werf ◽  
A.J. Matute ◽  
E. Delgado ◽  
C.A.M. Schurink ◽  
...  
Keyword(s):  
Emergency Department ◽  
Infectious Diseases ◽  
University Hospital ◽  
The University

scholarly journals Arctic Thunder: A Novel by R. Feagan

2011 ◽  
Vol 1 (1) ◽  
Author(s):  
Sandy Campbell
Keyword(s):  
Point Of View ◽  
The Arctic ◽  
The South ◽  
Traffic Light ◽  
Basketball Players ◽  
University Of Alberta ◽  
The North ◽  
Western Arctic ◽  
Turn Over ◽  
The University

Feagan, Robert. Arctic Thunder: A Novel. Toronto: Dundurn Press, 2010. Print. St. Albert is a small city, just north of Edmonton in Central Alberta.  In the opening pages of this book, thirteen-year-old Mike Watson and his team, the St. Albert Rams, win the Alberta Bantam Provincial box lacrosse championship.  Then his father, an RCMP officer, announces that they’ve been posted to Inuvik, which Mike describes as a place “somewhere inside the Arctic Circle and makes winter in St. Albert seem like summer”. The author, Robert Feagan, who lives in St. Albert, but spent much of his youth in RCMP posts across the Canadian Western Arctic, does a good job of presenting the struggles of a thirteen year old boy from the South trying to fit into the largely Inuit and Dene community in Inuvik. The story is definitely told from the point of view of a “white kid from the South”, except that Mike is part Zulu, so he sort of looks like he might fit in. Mike finds that teenagers are teenagers everywhere and when he goes to school he meets: the bully, the nerd whom everyone avoids and the super athletes, who in this case compete in the Arctic Games.  There is even a beautiful female nemesis, Gwen, who is one of the best basketball players Mike has every encountered. While well written and engaging, Feagan sometimes becomes a little didactic in educating the reader about the North.  Characters occasionally launch into unnaturally detailed explanations about things northern. Much of the tension between characters is also resolved too neatly.  Most of the core characters acquire self-understanding, turn over new leaves, and apologize to each other within a very few pages.  Much more realistic is the portrayal of the typical teenager, Mike, whispering a “Thank-you” to his Mom, long after she’s out of earshot. Through the course of the book, Mike (and the reader) come to appreciate what Inuvik, with its single traffic light and one retail store, has to offer.  Feagan works in a sensitive treatment of the role of the elders in the community and the healthy effects of living close to the land.  Of course, lacrosse, which no one plays in Inuvik, is an important thread through the story. Adult readers should not be put off by the fact that this is a young adult novel; it is a good Arctic read for anyone. Highly recommended: 4 out of 4 starsReviewer: Sandy Campbell Sandy is a Health Sciences Librarian at the University of Alberta, who has written hundreds of book reviews across many disciplines.  Sandy thinks that sharing books with children is one of the greatest gifts anyone can give. 

scholarly journals Morbidity and Mortality of Inpatients in the Department of Infectious Diseases of the University Hospital of Bobo-Dioulasso, Burkina Faso

2019 ◽  
Vol 09 (03) ◽  
pp. 171-182
Author(s):  
Armel Poda ◽  
Jacques Zoungrana ◽  
Arsène Héma ◽  
Ziemlé Clément Méda ◽  
Alexandre Boena ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Burkina Faso ◽  
Morbidity And Mortality ◽  
University Hospital ◽  
Bobo Dioulasso ◽  
The University

Obstructive Hydrocephalus in Children: Predictive factors of ventriculocisternostomy dysfunction at the CHU of Conakry.

2021 ◽  
Author(s):  
Ibrahima Sory Souare ◽  
Mohamed Lamine Sylla ◽  
Ibrahima Sory Jnr Souaré ◽  
Hugues Ghislain Atakla ◽  
Mohamed Cherif ◽  
...  
Keyword(s):  
Obstructive Hydrocephalus ◽  
Third Ventricle ◽  
Clinical Signs ◽  
Pediatric Neurosurgery ◽  
The Body ◽  
University Hospital ◽  
Cerebrospinal Fluid Leakage ◽  
Clinical Criteria ◽  
The University ◽  
Larger Sample

Abstract Context and Objective: The treatment of hydrocephalus is surgical and uses two (2) main methods to date: ventriculoperitoneal shunt and endoscopic ventriculocisternostomy. The latter offers the advantage of avoiding the implantation of a foreign body (valve) in the body. However, there are sometimes dysfunctions that can lead to the evolutionary continuation of hydrocephalus. The objective of this study is to identify factors predictive of endoscopic ventriculocisternostomy dysfunction in cases of obstructive hydrocephalus in children at the University Hospital Center in Conakry.Methods and Materials: This is a mixed analytical study of 32 cases of children aged 0-15 years who received endoscopic ventriculocisternostomy during the study period. Outcomes were evaluated according to Drake and Canadian Pediatric Neurosurgery Group clinical criteria. Results: The hospital frequency was 17% and a sex ratio (M/F) of 1.13. Clinical signs were dominated by progressive macrocraniality (93.8%), bulging fontanel (84.4%), ectasia of scalp veins (68.8%). cerebrospinal fluid leakage (9.4%) was the most frequent post-operative complication. According to age, VCS was successful in 16 infants (55.2%) and dysfunction in 13 (44.8%) while 2 children (66.7%) were successful with VCS versus 1 (33.3%) with dysfunction. We recorded one case of death.Conclusion: The factors often associated with the dysfunction of the endoscopic ventriculocisternostomy found in this study are essentially: age, bulging fontanelle, ectasia of the scalp veins, arachnoid adhesions, closure of the Sylvius aqueduct and pulsation of the bottom of the third ventricle. In the absence of a statistically significant relationship, it would be useful to analyse these parameters closely on a much larger sample.

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