scholarly journals Clinical cholera surveillance sensitivity in Bangladesh and implications for large-scale disease control

Author(s):  
Sonia T Hegde ◽  
Elizabeth C Lee ◽  
Ashraful Islam Khan ◽  
Stephen A Lauer ◽  
Md Taufiqul Islam ◽  
...  

Introduction A surveillance system that is sensitive to detecting high burden areas is critical for achieving widespread disease control. In 2014, Bangladesh established a nationwide, facility-based cholera surveillance system for Vibrio cholerae infection. We sought to measure the sensitivity of this surveillance system to detect cases to assess whether cholera elimination targets outlined by the Bangladesh national control plan can be adequately measured. Methods We overlaid maps of nationally-representative annual V. cholerae seroincidence onto maps of the catchment areas of facilities where confirmatory laboratory testing for cholera was conducted, and identified its spatial complement as surveillance greyspots, areas where cases likely occur but go undetected. We assessed surveillance system sensitivity and changes to sensitivity given alternate surveillance site selection strategies. Results We estimated that 69% of Bangladeshis (111.7 million individuals) live in surveillance greyspots, and that 23% (25.5 million) of these individuals live in areas with the highest V. cholerae infection rates. Conclusions The cholera surveillance system in Bangladesh has the ability to monitor progress towards cholera elimination goals among 31% of the country's population, which may be insufficient for accurately measuring progress. Increasing surveillance coverage, particularly in the highest risk areas, should be considered.

Based on an epidemiological survey,1 human TBEV neuroinfections may have an endemic emergent course, and natural foci are in full territorial expansion. Identified risk areas are Tulcea district, Transylvania, at the base of the Carpathian Mountains and the Transylvanian Alps.2,3 TBE has been a notifiable disease since 1996. Surveillance of TBE is not done at the country level, only regionally in some counties (northern/central/western part, close to Hungary). The passive surveillance system was implemented in 2008. However, there is no regular screening and the relative risk of contracting this disease is unknown. In 1999, an outbreak of TBE in humans was recorded with a total of at least 38 human cases.4


Author(s):  
J. Schüz ◽  
A. Olsson

Cancer is increasing worldwide. Th e Russian Federation is no exception in this regard with an increase of the total number of new cases predicted to rise from 529,062 in 2018 to 587,622 in 2040. Th e present high burden and increase in incident cases at the same time increases the pressure on healthcare infrastructure and related costs. Th us, primary and secondary prevention of cancer becomes essential. Occupational cancers related to exposure at the workplace are among the preventable cancer burden, due to the modifi ability of the risk through minimisation of occupational exposures and adequate worker protection. For the Russian Federation, some 20,000 cancers each year may be att ributable to occupation, but systematic recording is currently lacking. As information is also lacking on the absolute eff ect of various occupational carcinogens in the Russian workforce due to lack of large-scale epidemiological studies and because for many suspected occupational carcinogens the evidence may become stronger, the true burden may in fact be higher. Th e Russian Federation appears particularly suitable for research into occupational cancer given the sizable workforce, the heavy industr ialisation as well as the good documentation and workplace surveillance over time, so that results are both informative for the situation in the Russian Federation and on a global scale. Five challenging but not unfeasible steps of nationwide population-based cancer registration, development of a legal framework for record linkage of registries and data collections, recording of occupational cancers, large scale epidemiological occupational cancer research and rigorous implementation of worker protection on known carcinogens, lead the way to a continuously updated cancer control plan that includes the elimination of occupational cancer in the Russian Federation.


2020 ◽  
Author(s):  
Rui Sun ◽  
Disa Sauter

Getting old is generally seen as unappealing, yet aging confers considerable advantages in several psychological domains (North & Fiske, 2015). In particular, older adults are better off emotionally than younger adults, with aging associated with the so-called “age advantages,” that is, more positive and less negative emotional experiences (Carstensen et al., 2011). Although the age advantages are well established, it is less clear whether they occur under conditions of prolonged stress. In a recent study, Carstensen et al (2020) demonstrated that the age advantages persist during the COVID-19 pandemic, suggesting that older adults are able to utilise cognitive and behavioural strategies to ameliorate even sustained stress. Here, we build on Carstensen and colleagues’ work with two studies. In Study 1, we provide a large-scale test of the robustness of Carstensen and colleagues’ finding that older individuals experience more positive and less negative emotions during the COVID-19 pandemic. We measured positive and negative emotions along with age information in 23,629 participants in 63 countries in April-May 2020. In Study 2, we provide a comparison of the age advantages using representative samples collected before and during the COVID-19 pandemic. We demonstrate that older people experience less negative emotion than younger people during the prolonged stress of the COVID-19 pandemic. However, the advantage of older adults was diminished during the pandemic, pointing to a likely role of older adults use of situation selection strategies (Charles, 2010).


Water ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1122
Author(s):  
Monica Ionita ◽  
Viorica Nagavciuc

The role of the large-scale atmospheric circulation in producing heavy rainfall events and floods in the eastern part of Europe, with a special focus on the Siret and Prut catchment areas (Romania), is analyzed in this study. Moreover, a detailed analysis of the socio-economic impacts of the most extreme flood events (e.g., July 2008, June–July 2010, and June 2020) is given. Analysis of the largest flood events indicates that the flood peaks have been preceded up to 6 days in advance by intrusions of high Potential Vorticity (PV) anomalies toward the southeastern part of Europe, persistent cut-off lows over the analyzed region, and increased water vapor transport over the catchment areas of Siret and Prut Rivers. The vertically integrated water vapor transport prior to the flood peak exceeds 300 kg m−1 s−1, leading to heavy rainfall events. We also show that the implementation of the Flood Management Plan in Romania had positive results during the 2020 flood event compared with the other flood events, when the authorities took several precaution measurements that mitigated in a better way the socio-economic impact and risks of the flood event. The results presented in this study offer new insights regarding the importance of large-scale atmospheric circulation and water vapor transport as drivers of extreme flooding in the eastern part of Europe and could lead to a better flood forecast and flood risk management.


Author(s):  
Frederik Juhl Jørgensen ◽  
Mathias Osmundsen

Abstract Can corrective information change citizens’ misperceptions about immigrants and subsequently lead to favorable immigration opinions? While prior studies from the USA document how corrections about the size of minority populations fail to change citizens’ immigration-related opinions, they do not examine how other facts that speak to immigrants’ cultural or economic dependency rates can influence immigration policy opinions. To extend earlier work, we conducted a large-scale survey experiment fielded to a nationally representative sample of Danes. We randomly expose participants to information about non-Western immigrants’ (1) welfare dependency rate, (2) crime rate, and (3) proportion of the total population. We find that participants update their factual beliefs in light of correct information, but reinterpret the information in a highly selective fashion, ultimately failing to change their policy preferences.


2021 ◽  
pp. 194855062199962
Author(s):  
Jennifer S. Trueblood ◽  
Abigail B. Sussman ◽  
Daniel O’Leary

Development of an effective COVID-19 vaccine is widely considered as one of the best paths to ending the current health crisis. While the ability to distribute a vaccine in the short-term remains uncertain, the availability of a vaccine alone will not be sufficient to stop disease spread. Instead, policy makers will need to overcome the additional hurdle of rapid widespread adoption. In a large-scale nationally representative survey ( N = 34,200), the current work identifies monetary risk preferences as a correlate of take-up of an anticipated COVID-19 vaccine. A complementary experiment ( N = 1,003) leverages this insight to create effective messaging encouraging vaccine take-up. Individual differences in risk preferences moderate responses to messaging that provides benchmarks for vaccine efficacy (by comparing it to the flu vaccine), while messaging that describes pro-social benefits of vaccination (specifically herd immunity) speeds vaccine take-up irrespective of risk preferences. Findings suggest that policy makers should consider risk preferences when targeting vaccine-related communications.


2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Robert Bozick

Abstract Background Self-rated health (SRH) is one of the most commonly used summary measures of overall health and well-being available to population scientists due to its ease of administration in large-scale surveys and to its efficacy in predicting mortality. This paper assesses the extent to which SRH is affected by its placement before or after questions about bodyweight on a survey, and whether differences in placement on the questionnaire affects SRH’s predictive validity. Methods I assessed the validity of SRH in predicting the risk of mortality by comparing outcomes of sample members who were asked to rate their health before reporting on their bodyweight (the control group) and sample members who were asked to rate their health after reporting on their bodyweight (the treatment group). Both the control and treatment group were randomly assigned via an experiment administered as a module in a nationally representative sample of adults in the USA in 2019 (N = 2523). Results The odds of reporting a more favorable appraisal of health are 30% lower for sample members who were in the treatment group when compared with the control group. Additionally, the SRH of treatment group members is significantly associated with their risk of mortality, while the SRH of control group members is not. Conclusion The findings from this study suggest that for researchers to maximize the utility of SRH, closer attention needs to be paid to the context of the survey within which it asked. SRH is highly sensitive to the questions that precede it, and this sensitivity may in turn mischaracterize the true health of the population that the survey is intending to measure.


2021 ◽  
Vol 3 (5) ◽  
Author(s):  
Anirban Nath ◽  
Sourav Samanta ◽  
Saon Banerjee ◽  
Anamitra Anurag Danda ◽  
Sugata Hazra

AbstractThe paper through a critical appraisal of the agricultural practices in the Indian Sundarban deltaic region explores the tripartite problems of arsenic biomagnification, salinity of arable lands and ingress of agrochemical pollutants into the freshwater resources, which endanger the health, livelihood and food security of the rural population inhabiting the delta. The threefold problem has rendered a severe blow to the agrarian economy consequently triggering large-scale outmigration of the rural population from the region. Although recent studies have addressed these issues separately, the inter-connectivity among these elements and their possible long-term impact upon sustainability in the Sundarbans are yet to be elucidated. In the current scenario, the study emphasizes that the depleting freshwater resources is at the heart of the threefold problems affecting the Sundarbans. Owing to the heavy siltation of the local river systems, freshwater resources from the local ravines have salinized beyond the point of being used for agricultural purposes. At the same time, increasing salinity levels resulting from fluctuation of pre- and post-monsoon rainfall, frequent cyclones and capillary movement of salinized groundwater (primarily during the Rabi season) have severely hampered the agricultural practices. Salinization of above groundwater reserves has forced the farmers toward utilization of groundwater, which are lifted using STWs, especially for rice and other cultivations in the Rabi season. The Holocene aquifers of the region retain toxic levels of arsenic which are lifted during the irrigation process and are deposited on to the agricultural fields, resulting in bioaccumulation of As in the food products resourced from the area. The compound effect of consuming arsenic-contaminated food and drinking water has resulted in severe health issues recorded among the local population in the delta. Furthermore, due to the sub-optimal conditions for sustaining agriculture under saline stress, farmers often opt for the cultivation of post-green revolution high-yielding varieties, which require additional inputs of nitrogen-based fertilizers, organophosphate herbicides and pesticides that are frequently washed away by runoff from the watershed into the low-lying catchment areas of the biosphere reserve. Such practices have endangered the vulnerable conditions of local flora and fauna. In the present situation, the study proposes mitigation strategies which necessitate the smart use of locally obtainable resources like water, adaptable cultivars and sustainable agronomic practices like organic farming. The study also suggests engaging of conventional plant breeding strategies such as “Evolutionary plant breeding” for obtaining cultivars adapted to the shifting ecological conditions of the delta in the long run.


Sign in / Sign up

Export Citation Format

Share Document