scholarly journals A multi-dataset evaluation of frame censoring for task-based fMRI

2021 ◽  
Author(s):  
Michael S Jones ◽  
Zhenchen Zhu ◽  
Aahana Bajracharya ◽  
Austin Luor ◽  
Jonathan E Peelle

Subject motion during fMRI can affect our ability to accurately measure signals of interest. In recent years, frame censoring—that is, statistically excluding motion-contaminated data within the general linear model using nuisance regressors—has appeared in several task-based fMRI studies as a mitigation strategy. However, there have been few systematic investigations quantifying its efficacy. In the present study, we compared the performance of frame censoring to several other common motion correction approaches for task-based fMRI using open data and reproducible workflows. We analyzed eight datasets available on OpenNeuro.org representing eleven distinct tasks in child, adolescent, and adult participants. Performance was quantified using maximum t-values in group analyses, and ROI-based mean activation and split-half reliability in single subjects. We compared frame censoring to the use of 6 and 24 canonical motion regressors, wavelet despiking, robust weighted least squares, and untrained ICA-based denoising. Thresholds used to identify censored frames were based on both motion estimates (FD) and image intensity changes (DVARS). Relative to standard motion regressors, we found consistent improvements for modest amounts of frame censoring (e.g., 1-2% data loss), although these gains were frequently comparable to what could be achieved using other techniques. Importantly, no single approach consistently outperformed the others across all datasets and tasks. These findings suggest that although frame censoring can improve results, the choice of a motion mitigation strategy depends on the dataset and the outcome metric of interest.

2018 ◽  
Author(s):  
Brian D. Earp ◽  
Joshua T. Monrad ◽  
Marianne LaFrance ◽  
John A. Bargh ◽  
Lindsey Cohen ◽  
...  

Objective: Observer rating of pain is central to diagnosis and treatment in healthcare, especially in pediatrics. However, there are few studies examining potential biases in observer ratings of pediatric pain. Cohen et al. (2014) reported that adult participants rated a video of a child undergoing a needle stick as experiencing more pain when the child was described as a boy as compared to a girl, suggesting a possible gender bias. To confirm, clarify, and extend this finding, we conducted a replication experiment and follow-up study examining the role of explicit gender stereotypes in shaping such asymmetric judgments. Method: In an independent, pre-registered, direct replication and extension study with open data and materials (osf.io/6tj58), we showed participants the same video from Cohen et al. (2014), with the child described as a boy or a girl depending on condition. We then asked adults to rate how much pain the child experienced and displayed, how typical the child was in these respects, and how much they agreed with explicit gender stereotypes concerning pain response in boys versus girls. Results: Similar to Cohen et al. (2014), but with a larger and more demographically diverse sample, we found that the ‘boy’ was rated as experiencing more pain than the ‘girl’ despite identical clinical circumstances and identical pain behavior cross conditions. Controlling for explicit gender stereotypes eliminated the effect. Conclusions: Explicit gender stereotypes—e.g., that boys are more ‘stoic’ or girls are more emotive—may bias adult assessment of children’s pain.


2018 ◽  
Author(s):  
Pei Huang ◽  
Johan D. Carlin ◽  
Arjen Alink ◽  
Nikolaus Kriegeskorte ◽  
Richard N. Henson ◽  
...  

ABSTRACTWe evaluated the effectiveness of prospective motion correction (PMC) on a simple visual task when no deliberate subject motion was present. The PMC system utilizes an in-bore optical camera to track an external marker attached to the participant via a custom-moulded mouthpiece. The study was conducted at two resolutions (1.5mm vs 3mm) and under three conditions (PMC On and Mouthpiece On vs PMC Off and Mouthpiece On vs PMC Off and Mouthpiece Off). Multiple data analysis methods were conducted, including univariate and multivariate approaches, and we demonstrated that the benefit of PMC is most apparent for multi-voxel pattern decoding at higher resolutions. Additional testing on two participants showed that our inexpensive, commercially available mouthpiece solution produced comparable results to a dentist-moulded mouthpiece. Our results showed that PMC is increasingly important at higher resolutions for analyses that require accurate voxel registration across time.


NeuroImage ◽  
2016 ◽  
Vol 127 ◽  
pp. 11-22 ◽  
Author(s):  
M. Dylan Tisdall ◽  
Martin Reuter ◽  
Abid Qureshi ◽  
Randy L. Buckner ◽  
Bruce Fischl ◽  
...  

2019 ◽  
Vol 62 (5) ◽  
pp. 1326-1337 ◽  
Author(s):  
Brittany L. Perrine ◽  
Ronald C. Scherer ◽  
Jason A. Whitfield

Purpose Oral air pressure measurements during lip occlusion for /pVpV/ syllable strings are used to estimate subglottal pressure during the vowel. Accuracy of this method relies on smoothly produced syllable repetitions. The purpose of this study was to investigate the oral air pressure waveform during the /p/ lip occlusions and propose physiological explanations for nonflat shapes. Method Ten adult participants were trained to produce the “standard condition” and were instructed to produce nonstandard tasks. Results from 8 participants are included. The standard condition required participants to produce /pːiːpːiː.../ syllables smoothly at approximately 1.5 syllables/s. The nonstandard tasks included an air leak between the lips, faster syllable repetition rates, an initial voiced consonant, and 2-syllable word productions. Results Eleven oral air pressure waveform shapes were identified during the lip occlusions, and plausible physiological explanations for each shape are provided based on the tasks in which they occurred. Training the use of the standard condition, the initial voice consonant condition, and the 2-syllable word production increased the likelihood of rectangular oral air pressure waveform shapes. Increasing the rate beyond 1.5 syllables/s improved the probability of producing rectangular oral air pressure signal shapes in some participants. Conclusions Visual and verbal feedback improved the likelihood of producing rectangular oral air pressure signal shapes. The physiological explanations of variations in the oral air pressure waveform shape may provide direction to the clinician or researcher when providing feedback to increase the accuracy of estimating subglottal pressure from oral air pressure.


2020 ◽  
Vol 63 (11) ◽  
pp. 3877-3892
Author(s):  
Ashley Parker ◽  
Candace Slack ◽  
Erika Skoe

Purpose Miniaturization of digital technologies has created new opportunities for remote health care and neuroscientific fieldwork. The current study assesses comparisons between in-home auditory brainstem response (ABR) recordings and recordings obtained in a traditional lab setting. Method Click-evoked and speech-evoked ABRs were recorded in 12 normal-hearing, young adult participants over three test sessions in (a) a shielded sound booth within a research lab, (b) a simulated home environment, and (c) the research lab once more. The same single-family house was used for all home testing. Results Analyses of ABR latencies, a common clinical metric, showed high repeatability between the home and lab environments across both the click-evoked and speech-evoked ABRs. Like ABR latencies, response consistency and signal-to-noise ratio (SNR) were robust both in the lab and in the home and did not show significant differences between locations, although variability between the home and lab was higher than latencies, with two participants influencing this lower repeatability between locations. Response consistency and SNR also patterned together, with a trend for higher SNRs to pair with more consistent responses in both the home and lab environments. Conclusions Our findings demonstrate the feasibility of obtaining high-quality ABR recordings within a simulated home environment that closely approximate those recorded in a more traditional recording environment. This line of work may open doors to greater accessibility to underserved clinical and research populations.


Author(s):  
Ana Franco ◽  
Julia Eberlen ◽  
Arnaud Destrebecqz ◽  
Axel Cleeremans ◽  
Julie Bertels

Abstract. The Rapid Serial Visual Presentation procedure is a method widely used in visual perception research. In this paper we propose an adaptation of this method which can be used with auditory material and enables assessment of statistical learning in speech segmentation. Adult participants were exposed to an artificial speech stream composed of statistically defined trisyllabic nonsense words. They were subsequently instructed to perform a detection task in a Rapid Serial Auditory Presentation (RSAP) stream in which they had to detect a syllable in a short speech stream. Results showed that reaction times varied as a function of the statistical predictability of the syllable: second and third syllables of each word were responded to faster than first syllables. This result suggests that the RSAP procedure provides a reliable and sensitive indirect measure of auditory statistical learning.


Author(s):  
Virginie Crollen ◽  
Julie Castronovo ◽  
Xavier Seron

Over the last 30 years, numerical estimation has been largely studied. Recently, Castronovo and Seron (2007) proposed the bi-directional mapping hypothesis in order to account for the finding that dependent on the type of estimation task (perception vs. production of numerosities), reverse patterns of performance are found (i.e., under- and over-estimation, respectively). Here, we further investigated this hypothesis by submitting adult participants to three types of numerical estimation task: (1) a perception task, in which participants had to estimate the numerosity of a non-symbolic collection; (2) a production task, in which participants had to approximately produce the numerosity of a symbolic numerical input; and (3) a reproduction task, in which participants had to reproduce the numerosity of a non-symbolic numerical input. Our results gave further support to the finding that different patterns of performance are found according to the type of estimation task: (1) under-estimation in the perception task; (2) over-estimation in the production task; and (3) accurate estimation in the reproduction task. Moreover, correlation analyses revealed that the more a participant under-estimated in the perception task, the more he/she over-estimated in the production task. We discussed these empirical data by showing how they can be accounted by the bi-directional mapping hypothesis ( Castronovo & Seron, 2007 ).


Sign in / Sign up

Export Citation Format

Share Document