scholarly journals Surgical interventions targeting the nucleus caudalis: a systematic review and historical perspective.

Author(s):  
Brendan Santyr ◽  
Mohamad Abbass ◽  
Alan Chalil ◽  
Amirti Vivekanandan ◽  
Margaret Lauren Tindale ◽  
...  

Introduction: Chronic facial pain is a prevalent group of conditions and when refractory to common treatments poses a social and economic burden. The last decade has seen a multitude of advancements in the multimodal management of pain. Ablative or neuromodulatory interventions targeting the nucleus caudalis (NC) of the trigeminocervical complex is one such treatment that has remained underutilized. Methods: Here we present a systematic review of the literature and historical perspective regarding interventions targeting the NC. We examine the various intervention techniques, clinical indications, and procedural efficacy. A novel outcome reporting scheme was devised to allow comparison between studies using differing outcome reporting methods. Results: A review of the literature revealed 49 retrospective studies published over the last 80 years, reporting on 858 patients. The most common technique was the open NC dorsal root entry zone nucleotomy/tractotomy (n=515, 60.0%); however, there has been an emergence of novel approaches such as endoscopic (n=6, 0.7%) and spinal cord stimulation (n=20, 2.3%) in the last 10 years. Regardless of intervention technique or preoperative diagnosis, 90.4% of patients demonstrated some improvement from treatment. Conclusion: This systematic review highlights recent advancements in NC intervention technique and the wide range of facial pain syndromes for which these interventions show promising efficacy. New and less invasive techniques continue to emerge, however prospective studies remain absent in the literature. Future work should address efficacy comparisons between intervention type and preoperative diagnosis.

2016 ◽  
Vol 159 (1) ◽  
pp. 33-49 ◽  
Author(s):  
Aristotelis V. Kalyvas ◽  
Mark Hughes ◽  
Christos Koutsarnakis ◽  
Demetrios Moris ◽  
Faidon Liakos ◽  
...  

2015 ◽  
Vol 54 (05) ◽  
pp. 447-454 ◽  
Author(s):  
U. Mansmann ◽  
D. Lindoerfer

SummaryBackground: Patient registries are an important instrument in medical research. Often their structure is complex and their implementation uses composite software systems to meet the wide spectrum of challenges.Objectives: For the implementation of a registry, there is a wide range of commercial, open source, and self-developed systems available and a minimal standard for the critical appraisal of their architecture is needed.Methods: We performed a systematic review of the literature to define a catalogue of relevant criteria to construct a minimal appraisal standard.Results: The CIPROS list is developed based on 64 papers which were found by our systematic review. The list covers twelve sections and contains 72 items.Conclusions: The CIPROS list supports developers to assess requirements on existing systems and strengthens the reporting of patient registry software system descriptions. It can be a first step to create standards for patient registry software system assessments.


2014 ◽  
Vol 106 (9) ◽  
pp. dju217-dju217 ◽  
Author(s):  
N. S. Blencowe ◽  
P. Chana ◽  
R. N. Whistance ◽  
D. Stevens ◽  
N. A. C. S. Wong ◽  
...  

2020 ◽  
pp. 1-24
Author(s):  
SALVADOR VALERA ◽  
ALBA E. RUZ

Conversion is a key type of word-formation process in English, but the precise nature of the relation between base and derivative in conversion is rarely discussed, even if conversion is considered as a dynamic process. When it is considered explicitly, the relation has been described in terms of paradigmatic relations between lexemes, specifically homonymy or polysemy. This is usually without any specification of how converted words accommodate the conditions set by the definition of each of these relations, and as a special type of one or the other, because conversion-related words violate some of those conditions. This article is intended as a systematic review of the literature that discusses the relation between conversion-related words in English. We show that a wide range of proposals have been made to describe the relation: homonymy, heterosemy, homomorphy, zero-derivation (as a relation), polysemy, lexical extension, synsemy, hyponymy and paronymy. We review the extent to which each of these terms fits the relationship in major types of conversion, and argue that, if a relationship is to be described between conversion-related pairs, then Cruse's (1986) separation of semantic relations of a paradigmatic type from paronymic relations is of special relevance here. We propose that, regardless of the direction and type of meaning, paronymy applies across the various specific semantic patterns that conversion may involve. We emphasize, however, the possibility of several relations according to the type of conversion, i.e. different types of conversion may need description in terms of a different relation.


2021 ◽  
pp. 003452372110057
Author(s):  
Wander M van Baalen ◽  
Tamara de Groot ◽  
Liesbeth Noordegraaf-Eelens

Against an increasingly compartmentalized educational landscape, we have heard urgent calls for new modes of teaching and learning. In this light, educators from a variety of disciplinary backgrounds turned to transdisciplinarity and the arts for a possible response. The educational initiatives being developed and the related literature are situated across a wide range of themes, disciplines, and methodologies. The fragmented nature of the academic discussion inhibits our capacity to think through the implications of mobilizing the concept of transdisciplinarity within the arts and education. This study addresses the lack of an overview by conducting a systematic review of the literature characterized by a triangular interest in higher education, transdisciplinarity, and the arts. The documents under review amount to 458 unique scientific papers. In our results, we present a metaphorical scale – moving from buzzwords to a theoretically delineated usage – to make sense of the use and conceptualization of transdisciplinarity and we introduce three main ways how the arts are part of transdisciplinary educational compositions. In bringing together literature on education, the arts, and transdisciplinarity, we shed light on relevant similarities between thinking and doing that too often operates in isolation. As such, we aim to facilitate opportunities for mutual learning and present an improved vantage point from which to consider how decisions regarding particular conceptualizations and positionalities feed into our artistic and educational practices.


Folia Medica ◽  
2020 ◽  
Vol 62 (4) ◽  
pp. 703-711
Author(s):  
Georgi Popivanov ◽  
Daniela Stoyanova ◽  
Marina Konaktchieva ◽  
Roberto Cirocchi ◽  
Dimitar Penchev ◽  
...  

Introduction: Although ileosigmoid fistulas (ISFs) in Crohn’s disease (CD) are rare they can be quite challenging, especially for the inexperienced surgeons. Furthermore, current guidelines offer no clear recommendation regarding the surgical strategy in such cases. A systematic review of the literature to determine the best surgical strategy and a prospective case series are presented herein.  Materials and methods: The systematic review was performed according to PRISMA guidelines. A single-center prospective data-base from January 1, 2014 to August 20, 2019 is presented. Age, duration of CD, and the rates of ISF, emergency, preoperative diagnosis, type of surgery, type of stoma, and complications were analyzed and a prospective case series. Results: Eleven of 69 papers with a total of 505 patients were included in the systematic analysis. The rate of ISF was 3–5% of all CD patients. The combined preoperative detection rate of all modalities was 71%. Primary repair was performed in 42% of the cases; the rate of stoma was 31.5% with a similar proportion in primary repair and sigmoid resection.In the presented series, 35 of 176 patients with CD were operated (51% in an emergency setting). There were 7 cases with ISFs (4% of all and 20% of the operated patients). Preoperative diagnosis was made at 57%. Primary repair was performed in 71%, and a two-stage intervention with a stoma – in 58% of patients. Conclusions: Primary repair should be attempted in all cases in which the sigmoid colon is disease-free or is not involved in the adja-cent abscess. The synchronous resections are not a mandatory indication for the stoma, but rather a tailored approach is recommended with an evaluation of the risk factors. Based on the available literature, no clear recommendation regarding the type of stoma can be made.


2020 ◽  
Vol 19 (7) ◽  
pp. 1541-1550
Author(s):  
Rong Li ◽  
Gengqiu Tang ◽  
Xile Liu ◽  
Junni Li ◽  
Dong Wang ◽  
...  

This review aimed to provide a comprehensive overview of ethnobotanical uses, chemical constituents, posology, and toxicology of Hyptis  suaveolens, and to address the significant medicinal benefits in order to promote its application. An extensive and systematic review of the literature was undertaken and all relevant abstracts and full-text articles analyzed and included in the review. A wide range of traditional uses are cited in the literature, ranging from uses for malaria, constipation, stomach problems, renal inflammation to external uses in repelling insects and treating injuries such as lacerations and burnrelated damage to skin and tissues. To date, pharmacological studies have demonstrated the  significant activities of this plant that support uses such as antimicrobial, antidiabetic, antiulcer, and antiinflammatory. Numerous important phytochemicals, including 6 triterpenes, 8 diterpenes and 1 flavonoid have been isolated, identified and reported. The extracts and phytochemicals isolated from the plants show considerable potential for medicinal exploitation and utilization, including antimitotic, antiproliferative, cytotoxic, antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, anti-secretory, hepatoprotective, insecticidal, and acaricidal activities. As a medicinal plant, H. suaveolens is endowed with immense exploitation and utilization value and is widely used worldwide Therefore, further studies to fully elucidate its medicinal potential are warranted. Keywords: Hyptis suaveolens (L.) Poit, Ulcer Antimicrobial Inflammation, Diterpenes, Traditional medicine, Ethnopharmacology, Lamiaceae


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