scholarly journals Harmonized-Multinational qEEG Norms (HarMNqEEG)

2022 ◽  
Author(s):  
Min Li ◽  
Ying Wang ◽  
Carlos Lopez-Naranjo ◽  
Aini Ismafairus Abd Hamid ◽  
Alan C. Evans ◽  
...  

This paper extends our frequency domain quantitative electroencephalography (qEEG) methods pursuing higher sensitivity to detect Brain Developmental Disorders. Prior qEEG work lacked integration of cross-spectral information omitting important functional connectivity descriptors. Lack of geographical diversity precluded accounting for site-specific variance, increasing qEEG nuisance variance. We ameliorate these weaknesses. i) Create lifespan Hermitian Riemannian multinational qEEG norms for cross-spectral tensors. These norms result from the HarMNqEEG project fostered by the Global Brain Consortium. We calculate the norms with data from 9 countries, 12 devices, and 14 studies, including 1564 subjects. Instead of raw data, only anonymized metadata and EEG cross-spectral tensors were shared. After visual and automatic quality control developmental equations for the mean and standard deviation of qEEG traditional and Hermitian Riemannian descriptive parameters were calculated using additive mixed-effects models. We demonstrate qEEG "batch effects" and provide methods to calculate harmonized z-scores. ii) We also show that the multinational harmonized Hermitian Riemannian norms produce z-scores with increased diagnostic accuracy to predict brain dysfunction at school-age produced by malnutrition only in the first year of life. We provide data and software for constructing norms. iii) We offer open code and data to calculate different individual z-scores from the HarMNqEEG dataset. These results contribute to developing bias-free, low-cost neuroimaging technologies applicable in various health settings.

PEDIATRICS ◽  
1986 ◽  
Vol 78 (1) ◽  
pp. 146-150
Author(s):  
A. Kahn ◽  
D. Blum ◽  
M. F. Muller ◽  
L. Montauk ◽  
A. Bochner ◽  
...  

To determine possible characteristics of infant victims of sudden death, we examined 114 items related to the pre- and postnatal histories of 42 pairs of twins one of whom died of sudden infant death syndrome (SIDS) leaving a surviving sibling. Interviews with the parents were conducted after the occurrence of SIDS, and the data were checked with records held by gynecologists and pediatricians. To evaluate the specificity of any factors, we studied a control group of 42 age- and sex-matched pairs of twins, both of whom survived the first year of life. Only 11 of 114 characteristics were significantly related to SIDS: future victims had a smaller weight and height at birth, stayed longer in the nursery, and followed a moving object with their eyes, had head control, and smiled at a later age than their surviving siblings. They also fatigued more often during feeding (11/42) and had reduced arm and neck tonus (9/42). They were described as longer sleepers than their surviving siblings. During sleep, some SIDS twins, but no surviving twin, were found to be cyanotic at least once or pale (4/42) and were repeatedly covered with abundant sweat (8/42). In the control group of normal twins, the occurrence of most of these characteristics was found with a frequency comparable to that seen in the SIDS infants; the specificity of these characteristics is thus considered doubtful. The mean birth weight and height were significantly greater in the control group, and no control infant had an episode of cyanosis or pallor or repeated episodes of profuse sweating observed during their sleep. It is concluded that, if further research validates the occurrence of night hyperhydrosis in some future SIDS victims, this symptom could be a clinical risk factor.


Perception ◽  
1997 ◽  
Vol 26 (1_suppl) ◽  
pp. 235-235
Author(s):  
L I Leushina ◽  
V M Bondarko ◽  
A A Nevskaya

Colour discrimination was investigated in infants aged 4 – 14 months. 250 healthy subjects and 80 subjects with slight defects in basic visual functions (the risk group) participated. A coloured toy was moved in front of the subject and disappeared behind a screen, reappearing after 2 – 3 s at the other side. Sometimes when the toy was hidden, the experimenter replaced it with another one that differed only in colour: yellow was replaced by blue or vice versa (Y/B switch), or red by green or vice versa (R/G switch). The form and size of the toy remained constant. The emotional reaction of surprise showed whether the infant discriminated these colour pairs. The brightness of the stimuli was slightly varied make sure that the infant reacted to the change in colour rather than brightness. About 75% of healthy 4 – 5-month-olds showed good expressive reactions to the Y/B switch, and practically all children did so at 7 – 8 months. The discrimination of red and green develops more slowly: only at 12 months did practically all children show good reactions to the R/G switch. In all children, Y/B discrimination preceded R/G discrimination. The mean difference between the numbers of children discriminating these two pairs was 7.6%. The infants of the risk group were as good as their healthy age-mates in Y/B discrimination, but performed significantly less well on R/G: the mean difference between the numbers discriminating the former but not the latter was 17.0%. Possible reasons for the retardation of chromatic discrimination in the risk group are discussed.


2020 ◽  
Vol 99 (8) ◽  
pp. 898-906 ◽  
Author(s):  
E. Bernabé ◽  
H. Ballantyne ◽  
C. Longbottom ◽  
N.B. Pitts

Early exposure to sweet tastes predicts similar food preferences and eating behavior in later life and is associated with childhood obesity. The aim of this study was to explore the associations of early (during the first year of life) and subsequent intake of sugar-sweetened beverages (SSBs) with 4-y caries trajectories among Scottish young children. We used data from 1,111 Scottish children who were followed annually from age 12 to 48 mo (4 sweeps in total). SSB intake was reported by parents in every sweep. SSB intake was broken down into 2 components, the initial SSB intake and the deviation over time from that initial value. Childhood dental caries was clinically determined (including noncavitated and cavitated lesions) every year. The association of SSB intake with baseline decayed, missing, and filled tooth surfaces (dmfs) (intercept) and rate of change in dmfs over time (slope) was examined in 2-level linear mixed-effects models, with repeated observations nested within children. Both the initial SSB intake and the deviation from the initial SSB intake were positively associated with steeper caries trajectories. By sweep 4, the predicted mean dmfs difference was 1.73 between children with low and high initial SSB intake (1 standard deviation below and above the mean) and 1.17 between children with low and high deviation from their initial SSB intake (1 SD below and above the mean). The findings of this prospective study among Scottish young children provide evidence that the introduction of SSBs during the first year of life can put children in a trajectory of high levels of dental caries. They support current recommendations to avoid sugars for very young children and interventions targeting early feeding practices for caries prevention.


1978 ◽  
Vol 90 (2) ◽  
pp. 275-281 ◽  
Author(s):  
Ø. R. Dýrmundsson

SummaryThe paper reports on a study, conducted in four successive seasons, of sexual development and breeding activity in females of the Iceland breed, the only breed of sheep kept in the country. The ewe lambs normally attained puberty in their first year of life, on average at 7 months of age, with marked individual variation in both age and body weight at first oestrus. Ewe lambs always showed oestrus on average slightly later than mature ewes (2–9 years), the mean date of onset of the breeding season of the latter being 8 December, however, with considerable individual variation. Furthermore, ewe lambs had a shorter breeding season (1–4 months) than ewes (4–6 months) and they appeared to experience more silent heats resulting in less regular cyclic activity. There seemed to be a minor increase in the duration of the oestrous cycle with age and ewe lambs clearly exhibited shorter oestrus (heat) than ewes. With seasonal breeding activity ranging from November to May the mid-breeding season occurs some 4–7 weeks after the shortest day.


2005 ◽  
Vol 8 (5) ◽  
pp. 501-508 ◽  
Author(s):  
Ramoteme L Mamabolo ◽  
Marianne Alberts ◽  
Nelia P Steyn ◽  
Henriette A Delemarre-van de Waal ◽  
Naomi S Levitt

AbstractObjectivesTo determine the prevalence of stunting, wasting and overweight and their determinants in 3-year-old children in the Central Region of Limpopo Province, South Africa.DesignProspective cohort study.SettingRural villages in the Central Region of the Limpopo Province, South Africa.SubjectsOne hundred and sixty-two children who were followed from birth were included in the study. Anthropometric measurements and sociodemographic characteristics of the children were recorded.ResultsHeight-for-age Z-scores were low, with a high prevalence of stunting (48%). The children also exhibited a high prevalence of overweight (22%) and obesity (24%). Thirty-one (19%) children were both stuntedandoverweight. Gaining more weight within the first year of life increased the risk of being overweight at 3 years by 2.39 times (95% confidence interval (CI) 1.96–4.18) while having a greater length at 1 year was protective against stunting (odds ratio (OR) 0.41; 95% CI 0.17–0.97). Having a mother as a student increased the risk for stunting at 3 years by 18.21 times (95% CI 9.46–34.74) while having a working mother increased the risk for overweight by 17.87 times (95% CI 8.24–38.78). All these factors also appeared as risks or as being protective in children who were both overweight and stunted, as did living in a household having nine or more persons (OR 5.72; 95% CI 2.7–12.10).ConclusionThe results of this study highlight the importance of evaluating anthropometric status in terms of both stunting and overweight. Furthermore, it is important to realise the importance of normal length and weight being attained at 1 year of age, since these in turn predict nutritional status at 3 years of age.


2020 ◽  
Vol 70 (12) ◽  
pp. 4332-4335

Vitamin D is essential for calcium absorption and for maintaining bone health in the pediatric population. We conducted a retrospective study to establish the profile of a child aged under 3 years old with vitamin D deficiency in the context of correct prophylaxis, on a cohort of 49 children from two general practitioner offices. From the study group 30.6% of children (15 cases) had low vitamin D levels. The mean serum 25(OH)D level was 41.5±16.6 ng/ml. Regarding nutrition in the first year of life, breastfeeding predominated (83.7% of patients), and only 8.16% of patients had clinical signs of rickets. So, low serum levels of vitamin D can also be found in children who have successfully received correct prophylaxis with vitamin D. Keywords: vitamin D, children, rickets


2020 ◽  
Vol 5 (4) ◽  
pp. 67-80
Author(s):  
Kasandra Szklarczyk ◽  
◽  
Wiktoria Sztandarowicz ◽  
Emilia Szyjkowska ◽  
Paulina Sak ◽  
...  

Introduction. Stroke is a clinical syndrome in which focal or global brain dysfunction suddenly occurs. Despite the progress in diagnostics and treatment options that has been noticeable in recent years, stroke is the third most common cause of death in industrialized countries. In Poland, there are 60,000 people after a stroke every year, half of them die during the first year. Stroke patients often become dependent and needs help from other people. Aim. The aim of this study is to analyze selected aspects of nursing care provided to a patient after an ischemic stroke. Material and methods. Analysis of available literature related to issue of stroke and nursing care in patients after stroke as well as mapping medical diagnosis and interventions using the INCP ® dictionary. Results. Using the ICNP classification allows to show the patient's state of health after a stroke and plan nursing care based on uniform professional terminology.


Author(s):  
Kutay Bahadir ◽  
Bilgesu Arikan-Ergun ◽  
Atilla Halil Elhan ◽  
Ergun Ergun ◽  
Tanju Aktug

Abstract Introduction Sacrospinal anomalies that may accompany anorectal malformations may cause fecal and urinary incontinence despite proper anomaly treatment. The sacral ratio has been suggested in the determination of both the prognosis in terms of incontinence and the need for further examination for sacrospinal anomalies. The normal and clinically decisive values of sacral ratio are given differently in publications. We aimed to determine the distribution of the sacral ratio in children under 12 months and to develop the sacral ratio percentile card that will enable one to give an age-independent parametric result in clinical evaluations. Materials and Methods The files of patients under 1 year of age who had anteroposterior direct radiography including pelvis were reviewed retrospectively. Sacral ratio was studied for 360 patients, 30 patients per month. Percentile card was developed with LMS software and reference values were used as 1, 2, 3, 4, and 10%. Results The lowest sacral ratio value was 0.514 and the highest value was 0.936. There was no statistical difference between the mean sacral ratio of the cases when they were classified on a monthly basis (p = 0.191). Low percentile values were found slightly different at first 4 months of age. Conclusion Although the mean of sacral ratio does not change significantly during the first year of life, values that are considered pathological for patients are within different percentile limits depending on age. Instead of using sacral ratio with some clinically decisive values, we think that parametric evaluation with the help of the percentile card will increase its clinical value.


PEDIATRICS ◽  
1990 ◽  
Vol 86 (2) ◽  
pp. 193-196
Author(s):  
Harry Bard ◽  
Janie Prosmanne

A study was devised to determine whether levels of fetal hemoglobin (HbF) synthesis are elevated in infants with bronchopulmonary dysplasia (BPD) when compared with the levels of HbF synthesis found in normal control infants. Twelve infants with BPD, whose postconceptional ages ranged from 40 to 62 weeks, were studied. The mean (±SD) gestational age and birth weight was 29 ± 1.9 weeks and 1289 ± 376 g, respectively. Elevation infants matched for birth weight, gestational age, and postnatal age served as the control subjects. Blood samples were incubated in an amino acid mixture containing [14C]leucine. The adult hemoglobin and HbF were then separated by column chromatography on diethylaminoethyl-Sephadex. The results demonstrated that the mean (±SD) level of HbF synthesis in infants with BPD was significantly higher than that in the control infants (42.6 ± 22.9% vs 18.8 ± 12.8%; P < .01). When levels of HbF synthesis in the infants with BPD and the control infants were compared with data previously reported in normal infants, 7 of the 12 infants with BPD, but none of the control infants, were synthesizing amounts of HbF greater than would be expected for their postconceptional age. The results suggest that cardiopulmonary insufficiency could stimulate HbF synthesis during the first year of life as a result of an erythropoietic response to hypoxemia.


2014 ◽  
Vol 5 (2) ◽  
pp. 142-151 ◽  
Author(s):  
S. L. Loy ◽  
K. N. S. Sirajudeen ◽  
J. M. Hamid Jan

Although numerous studies have been conducted to examine the causal factors of childhood obesity, the implications of intrauterine oxidative stress on early postnatal adiposity development remain to be elucidated. The Universiti Sains Malaysia Birth Cohort Study aimed to investigate the effects of prenatal oxidative stress levels on the development of infant adiposity during the first year of life. This study was conducted on the healthy pregnant women aged 19–40 years, from April 2010 to December 2012 in Kelantan, Malaysia. Maternal blood samples were drawn in the second trimester to analyse for oxidative stress markers. Infant anthropometric measurements were taken at birth, 2, 6 and 12 months of age. A total of 153 pregnant women and full-term infants were included in the analysis. Statistical test was conducted by using multiple linear regression. Through the infant first year of life, as maternal DNA damage level in the second trimester increased, infant weights at birth (β=−0.122, P<0.001), 2 months (β=−0.120, P=0013), 6 months (β=−0.209, P=0.003) and 12 months of age (β=−0.241, P=0.006) decreased after adjusting for confounders. Similar results were noted when infant body mass index-for-age Z-scores and triceps skinfold-for-age Z-scores were used as the adiposity indicators. In conclusion, the present study shows a consistent inverse association between maternal DNA damage and infant adiposity during the first year of life. These infants with reduced growth and adiposity in early postnatal life may have a high tendency to experience catch-up growth during childhood, which could be strongly associated with later obesity.


Sign in / Sign up

Export Citation Format

Share Document