scholarly journals Deep Learning Strategies for Differential Expansion Microscopy

2019 ◽  
Author(s):  
Domenico L. Gatti ◽  
Suzan Arslanturk ◽  
Sinan Lal ◽  
Bhanu P. Jena
Keyword(s):  
Machine Learning ◽  
Deep Learning ◽  
Learning Strategies ◽  
Learning Approaches ◽  
Volumetric Expansion ◽  
Anisotropic Character ◽  
Differential Expansion

Differential expansion microscopy (DiExM) achieves greater than 500-fold volumetric expansion of biological specimens without loss of cellular antigens. The anisotropic character of this expansion, which affects tissues, cells, organelles and even sub-organelle features, requires the application of novel machine learning approaches to extract accurate and meaningful morphological and biochemical information from DiExM images. Here we describe current strategies to achieve this goal.

scholarly journals A Review of Recent Deep Learning Approaches in Human-Centered Machine Learning

Sensors ◽  
2021 ◽  
Vol 21 (7) ◽  
pp. 2514
Author(s):  
Tharindu Kaluarachchi ◽  
Andrew Reis ◽  
Suranga Nanayakkara
Keyword(s):  
Machine Learning ◽  
Deep Learning ◽  
Review Paper ◽  
Learning Systems ◽  
Learning Approaches ◽  
Application Development ◽  
Research Gaps ◽  
Domain Experts ◽  
Working Definition ◽  
Real World Application

After Deep Learning (DL) regained popularity recently, the Artificial Intelligence (AI) or Machine Learning (ML) field is undergoing rapid growth concerning research and real-world application development. Deep Learning has generated complexities in algorithms, and researchers and users have raised concerns regarding the usability and adoptability of Deep Learning systems. These concerns, coupled with the increasing human-AI interactions, have created the emerging field that is Human-Centered Machine Learning (HCML). We present this review paper as an overview and analysis of existing work in HCML related to DL. Firstly, we collaborated with field domain experts to develop a working definition for HCML. Secondly, through a systematic literature review, we analyze and classify 162 publications that fall within HCML. Our classification is based on aspects including contribution type, application area, and focused human categories. Finally, we analyze the topology of the HCML landscape by identifying research gaps, highlighting conflicting interpretations, addressing current challenges, and presenting future HCML research opportunities.

scholarly journals Detection of Malicious Software by Analyzing Distinct Artifacts Using Machine Learning and Deep Learning Algorithms

Electronics ◽  
2021 ◽  
Vol 10 (14) ◽  
pp. 1694
Author(s):  
Mathew Ashik ◽  
A. Jyothish ◽  
S. Anandaram ◽  
P. Vinod ◽  
Francesco Mercaldo ◽  
...  
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Deep Learning ◽  
Support Vector ◽  
Malware Analysis ◽  
Learning Approaches ◽  
Dynamic Features ◽  
System Calls ◽  
Prevention Methods ◽  
Structural Aspects

Malware is one of the most significant threats in today’s computing world since the number of websites distributing malware is increasing at a rapid rate. Malware analysis and prevention methods are increasingly becoming necessary for computer systems connected to the Internet. This software exploits the system’s vulnerabilities to steal valuable information without the user’s knowledge, and stealthily send it to remote servers controlled by attackers. Traditionally, anti-malware products use signatures for detecting known malware. However, the signature-based method does not scale in detecting obfuscated and packed malware. Considering that the cause of a problem is often best understood by studying the structural aspects of a program like the mnemonics, instruction opcode, API Call, etc. In this paper, we investigate the relevance of the features of unpacked malicious and benign executables like mnemonics, instruction opcodes, and API to identify a feature that classifies the executable. Prominent features are extracted using Minimum Redundancy and Maximum Relevance (mRMR) and Analysis of Variance (ANOVA). Experiments were conducted on four datasets using machine learning and deep learning approaches such as Support Vector Machine (SVM), Naïve Bayes, J48, Random Forest (RF), and XGBoost. In addition, we also evaluate the performance of the collection of deep neural networks like Deep Dense network, One-Dimensional Convolutional Neural Network (1D-CNN), and CNN-LSTM in classifying unknown samples, and we observed promising results using APIs and system calls. On combining APIs/system calls with static features, a marginal performance improvement was attained comparing models trained only on dynamic features. Moreover, to improve accuracy, we implemented our solution using distinct deep learning methods and demonstrated a fine-tuned deep neural network that resulted in an F1-score of 99.1% and 98.48% on Dataset-2 and Dataset-3, respectively.

scholarly journals Analysis of the Nosema Cells Identification for Microscopic Images

Sensors ◽  
2021 ◽  
Vol 21 (9) ◽  
pp. 3068
Author(s):  
Soumaya Dghim ◽  
Carlos M. Travieso-González ◽  
Radim Burget
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Image Processing ◽  
Deep Learning ◽  
The Other ◽  
Support Vector ◽  
Learning Approaches ◽  
Microscopic Images ◽  
Trained Neural Network ◽  
Nosema Disease

The use of image processing tools, machine learning, and deep learning approaches has become very useful and robust in recent years. This paper introduces the detection of the Nosema disease, which is considered to be one of the most economically significant diseases today. This work shows a solution for recognizing and identifying Nosema cells between the other existing objects in the microscopic image. Two main strategies are examined. The first strategy uses image processing tools to extract the most valuable information and features from the dataset of microscopic images. Then, machine learning methods are applied, such as a neural network (ANN) and support vector machine (SVM) for detecting and classifying the Nosema disease cells. The second strategy explores deep learning and transfers learning. Several approaches were examined, including a convolutional neural network (CNN) classifier and several methods of transfer learning (AlexNet, VGG-16 and VGG-19), which were fine-tuned and applied to the object sub-images in order to identify the Nosema images from the other object images. The best accuracy was reached by the VGG-16 pre-trained neural network with 96.25%.

scholarly journals A Review of Computer-Aided Expert Systems for Breast Cancer Diagnosis

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2764
Author(s):  
Xin Yu Liew ◽  
Nazia Hameed ◽  
Jeremie Clos
Keyword(s):  
Breast Cancer ◽  
Machine Learning ◽  
Deep Learning ◽  
Main Process ◽  
Learning Approaches ◽  
Learning Methods ◽  
Advantages And Disadvantages ◽  
Computer Aided ◽  
Conventional Methods ◽  
The Impact

A computer-aided diagnosis (CAD) expert system is a powerful tool to efficiently assist a pathologist in achieving an early diagnosis of breast cancer. This process identifies the presence of cancer in breast tissue samples and the distinct type of cancer stages. In a standard CAD system, the main process involves image pre-processing, segmentation, feature extraction, feature selection, classification, and performance evaluation. In this review paper, we reviewed the existing state-of-the-art machine learning approaches applied at each stage involving conventional methods and deep learning methods, the comparisons within methods, and we provide technical details with advantages and disadvantages. The aims are to investigate the impact of CAD systems using histopathology images, investigate deep learning methods that outperform conventional methods, and provide a summary for future researchers to analyse and improve the existing techniques used. Lastly, we will discuss the research gaps of existing machine learning approaches for implementation and propose future direction guidelines for upcoming researchers.

Investigation of Machine Learning and Deep Learning Approaches for Detection of Mild Traumatic Brain Injury from Human Sleep Electroencephalogram

2021 ◽  
Author(s):  
Manoj Vishwanath ◽  
Salar Jafarlou ◽  
Ikhwan Shin ◽  
Nikil Dutt ◽  
Amir M. Rahmani ◽  
...  
Keyword(s):  
Machine Learning ◽  
Traumatic Brain Injury ◽  
Deep Learning ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Learning Approaches ◽  
Human Sleep

scholarly journals PlotMI: visualization of pairwise interactions and positional preferences learned by a deep learning model from sequence data

2021 ◽  
Author(s):  
Tuomo Hartonen ◽  
Teemu Kivioja ◽  
Jussi Taipale
Keyword(s):  
Machine Learning ◽  
Deep Learning ◽  
Sequence Data ◽  
Predictive Performance ◽  
Learning Model ◽  
Biological Research ◽  
Learning Approaches ◽  
Learning Models ◽  
Model Interpretation ◽  
Pairwise Interactions

Deep learning models have in recent years gained success in various tasks related to understanding information coded in the DNA sequence. Rapidly developing genome-wide measurement technologies provide large quantities of data ideally suited for modeling using deep learning or other powerful machine learning approaches. Although offering state-of-the art predictive performance, the predictions made by deep learning models can be difficult to understand. In virtually all biological research, the understanding of how a predictive model works is as important as the raw predictive performance. Thus interpretation of deep learning models is an emerging hot topic especially in context of biological research. Here we describe plotMI, a mutual information based model interpretation strategy that can intuitively visualize positional preferences and pairwise interactions learned by any machine learning model trained on sequence data with a defined alphabet as input. PlotMI is freely available at https://github.com/hartonen/plotMI.

scholarly journals Comparison between Deep Learning and Tree-Based Machine Learning Approaches for Landslide Susceptibility Mapping

Water ◽  
2021 ◽  
Vol 13 (19) ◽  
pp. 2664
Author(s):  
Sunil Saha ◽  
Jagabandhu Roy ◽  
Tusar Kanti Hembram ◽  
Biswajeet Pradhan ◽  
Abhirup Dikshit ◽  
...  
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Deep Learning ◽  
Landslide Susceptibility ◽  
Learning Model ◽  
Susceptibility Mapping ◽  
Landslide Susceptibility Mapping ◽  
Learning Approaches ◽  
Statistical Measures ◽  
Deep Learning Model

The efficiency of deep learning and tree-based machine learning approaches has gained immense popularity in various fields. One deep learning model viz. convolution neural network (CNN), artificial neural network (ANN) and four tree-based machine learning models, namely, alternative decision tree (ADTree), classification and regression tree (CART), functional tree and logistic model tree (LMT), were used for landslide susceptibility mapping in the East Sikkim Himalaya region of India, and the results were compared. Landslide areas were delimited and mapped as landslide inventory (LIM) after gathering information from historical records and periodic field investigations. In LIM, 91 landslides were plotted and classified into training (64 landslides) and testing (27 landslides) subsets randomly to train and validate the models. A total of 21 landslide conditioning factors (LCFs) were considered as model inputs, and the results of each model were categorised under five susceptibility classes. The receiver operating characteristics curve and 21 statistical measures were used to evaluate and prioritise the models. The CNN deep learning model achieved the priority rank 1 with area under the curve of 0.918 and 0.933 by using the training and testing data, quantifying 23.02% and 14.40% area as very high and highly susceptible followed by ANN, ADtree, CART, FTree and LMT models. This research might be useful in landslide studies, especially in locations with comparable geophysical and climatological characteristics, to aid in decision making for land use planning.

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