scholarly journals Antibacterial activity of hinokitiol against both antibiotic‐resistant and ‐susceptible pathogenic bacteria that predominate in the oral cavity and upper airways

2019 ◽  
Vol 63 (6) ◽  
pp. 213-222 ◽  
Author(s):  
Hisanori Domon ◽  
Takumi Hiyoshi ◽  
Tomoki Maekawa ◽  
Daisuke Yonezawa ◽  
Hikaru Tamura ◽  
...  
Polibotánica ◽  
2015 ◽  
Vol 0 (39) ◽  
Author(s):  
Edgar García-Sánchez ◽  
César B. Ramírez-López ◽  
Rosa E. Martínez-Muñoz ◽  
Alberto Flores-García ◽  
Rosa E. del Río ◽  
...  

2020 ◽  
Vol 25 (3) ◽  
pp. 456-461
Author(s):  
Rizal Dwinto Rochman ◽  
Titiek Sunartatie ◽  
Usamah Afiff

Research to discover new antibacterial agent has been increasing due to the increasing number of pathogenic bacteria become antibiotic-resistant. Microbiomes in soil mold have antibacterial potency by producing secondary metabolites. The aim of this research was to isolate soil molds from the Faculty of Forestry Arboretum at IPB University. Arboretum’s soil was sampled ± 7.5 g from several points with maximum depth of 15 cm from surface. Mold isolate were cultivated for 28 days using waterbath shaker. Cultivated mycelium and soil filtrate were then separated and extracted using different methods and solvents, prior to antibacterial activity test using agar well diffusion method. Six isolates from Aspergillus, Penicillium, Paecilomyces, and Verticilium were used in this research. Cultivatation using sabouraud dextrose broth (SDB) contains pepton and dextrose in 25°C capable of stimulating mold growth. The research showed the result of secondary metabolit had antibacterial characteristic toward tested bacteria. The results of antibacterial activity test on both mycelium and soil filtrate extract showed that soil mold isolates had antibacterial activity against Staphylococcus aureus and Escherichia coli. Isolate 103A originated from soil filtrate formed the largest inhibition zone on both tested pathogens.   Keywords: antibacteria, mycelium, soil filtrate, soil mold


Author(s):  
Md. Amdadul Huq

The present study highlights a simple and eco-friendly method for the biosynthesis of silver nanoparticles (AgNPs) using Lysinibacillus xylanilyticus strain MAHUQ-40. Also, the synthesized AgNPs were used to investigate their antibacterial activity and mechanisms against antibiotic-resistant pathogens. Biosynthesis of AgNPs was confirmed by ultraviolet–visible spectroscopy, and then, they were characterized by field emission-transmission electron microscopy (FE-TEM), X-ray diffraction (XRD), dynamic light scattering (DLS), and fourier transform-infrared (FTIR). The toxicity of AgNPs against two pathogenic bacteria was evaluated. The UV–vis spectral scanning showed the peak for synthesized AgNPs at 438 nm. Under FE-TEM, the synthesized AgNPs were spherical with diameter ranges from 8 to 30 nm. The XRD analysis revealed the crystallinity of synthesized AgNPs. FTIR data showed various biomolecules including proteins and polysaccharides that may be involved in the synthesis and stabilization of AgNPs. The resultant AgNPs showed significant antibacterial activity against tested pathogens. The MICs (minimum inhibitory concentrations) and MBCs (minimum bactericidal concentrations) of the AgNPs synthesized by strain MAHUQ-40 were 3.12 and 12.5 μg/ml, respectively, against Vibrio parahaemolyticus and 6.25 and 25 μg/ml, respectively, against Salmonella Typhimurium. FE-TEM analysis showed that the biogenic AgNPs generated structural and morphological changes and damaged the membrane integrity of pathogenic bacteria. Our findings showed the potentiality of L. xylanilyticus MAHUQ-40 to synthesis AgNPs that acted as potent antibacterial material against pathogenic bacterial strains.


2015 ◽  
Vol 18 (1) ◽  
pp. 53-60
Author(s):  
Ashish Kumar Sarker ◽  
Md Anwarul Haque ◽  
Mohammad Sayful Islam ◽  
Md Ajijur Rahman ◽  
Md Anwar Ul Islam

To combat the increasing numbers of antibiotic resistant strains of pathogenic bacteria new source of antibacterial agents are desperately needed. This study was aimed to discover new marine bacteria having antibacterial activity from marine soil samples of Sundarbans, Bangladesh. Using starch-casein-nitrate-agar medium thirty nine marine bacteria colonies were isolated as pure isolates from nine marine soil samples. Each of the isolates was preserved in both short term and long term basis. Based on the aerial and substrate mycelia color of the isolates they were grouped into five color series and were screened for their antibacterial activity against a series of test bacteria. Among thirty nine pure isolates twenty four isolates (61.5%) exhibited moderate to high activity against three grampositive and four gram-negative bacteria. This is due to the antibacterial metabolites secreted in the medium by most of the isolates. It suggested that Sundarbans may be an interesting, valuable and potential source for the exploration of novel marine bacteria with the potential to yield useful new antibacterial secondary metabolites of pharmaceutical interest.Bangladesh Pharmaceutical Journal 18(1): 53-60, 2015


2012 ◽  
Vol 1 (1) ◽  
pp. 110 ◽  
Author(s):  
Belal J Muhialdin ◽  
Zaiton Hassan ◽  
Mohamed Muftah Ahmed Imdakim ◽  
Fredy Kesnawan Shah Abdul Kahar ◽  
Mohamed Mustafa Aween

<p>Contamination of foodstuff with foodborne and pathogenic bacteria are global issue and it is serious hazard for the health of the human. Lactic acid bacteria are well known for their health properties and their antimicrobial activity against spoilage and pathogenic bacteria. In this study, three isolates <em>Lactobacillus fermentum </em>Te007,<em> Pediococcus pentosaceus </em>Te010, <em>L. pentosus </em>G004 isolated from Malaysian fermented foods and fruits such as (tempeh, tempoyak, guava and banana) were evaluated for their antibacterial activity and antibiotic resistant against Gram-positive and Gram-negative bacteria by dual agar overlay method. The three isolates inhibited the growth of indicator bacteria and the activity was varied between weak and strong. All the isolates were resistant to the antibiotic nalidixic acid and vancomycin. The tested bacteria can be added to food as antibacterial agents to prevent the growth of harmful microorganisms.</p>


Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
MI Aguilar ◽  
Y Piñón ◽  
A Mejía ◽  
G Díaz-Ruiz ◽  
S Sánchez-Nieto ◽  
...  

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