Fetal and maternal outcomes after maternal biologic use during conception and pregnancy: a systematic review and meta‐analysis

This systematic review and meta-analysis aimed to examine the impact of different gestational-diabetes (GDM) diagnostic-criteria on the risk of adverse-maternal-outcomes. The search process encompassed PubMed (Medline), Scopus, and Web of Science databases to retrieve original, population-based studies with the universal GDM screening approach, published in English language and with a focus on adverse-maternal-outcomes up to January 2020. According to GDM diagnostic criteria, the studies were classified into seven groups. A total of 49 population-based studies consisting of 1409018 pregnant women with GDM and 7,667,546 non-GDM counterparts were selected for data analysis and knowledge synthesis. Accordingly, the risk of adverse-maternal-outcomes including primary-cesarean, induction of labor, maternal-hemorrhage, and pregnancy-related-hypertension, overall, regardless of GDM diagnostic-criteria and in all diagnostic-criteria subgroups were significantly higher than non-GDM counterparts. However, in meta-regression, the increased risk was not influenced by the GDM diagnostic-classification and the magnitude of the risks among patients, using the IADPSG criteria-classification as the most strict-criteria, was similar to other criteria. In conclusion, a reduction in the diagnostic-threshold increased the prevalence of GDM, but the risk of adverse-maternal-outcome was not different among those women who were diagnosed through more or less intensive strategies. Our review findings can empower health-care-providers to select the most cost-effective approach for the screening of GDM among pregnant women.

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Maternal outcomes of cesarean section performed at early gestational ages: a systematic review and meta-analysis

American Journal of Obstetrics & Gynecology MFM ◽

10.1016/j.ajogmf.2021.100360 ◽

2021 ◽

pp. 100360

Author(s):

Chiara Cerra ◽

Roberta Morelli ◽

Daniele Di Mascio ◽

Danilo Buca ◽

Francesca Di Sebastiano ◽

...

Keyword(s):

Systematic Review ◽

Cesarean Section ◽

Meta Analysis ◽

Maternal Outcomes

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Authors’ reply re: Uterine caesarean closure techniques affect ultrasound findings and long‐term maternal outcomes: a systematic review and meta‐analysis

BJOG An International Journal of Obstetrics & Gynaecology ◽

10.1111/1471-0528.15601 ◽

2019 ◽

Vol 126 (6) ◽

pp. 815-816

Author(s):

Sanne I. Stegwee ◽

Christianne J. M. de Groot ◽

Cornelis B. Lambalk ◽

Judith A. F. Huirne

Keyword(s):

Systematic Review ◽

Meta Analysis ◽

Maternal Outcomes ◽

Ultrasound Findings

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The effects of hands on and hands off/poised techniques on maternal outcomes: A systematic review and meta-analysis

Midwifery ◽

10.1016/j.midw.2020.102712 ◽

2020 ◽

Vol 87 ◽

pp. 102712 ◽

Cited By ~ 1

Author(s):

Jing Huang ◽

Hong Lu ◽

Yu Zang ◽

Lihua Ren ◽

Chunying Li ◽

...

Keyword(s):

Systematic Review ◽

Meta Analysis ◽

Maternal Outcomes ◽

Hands On

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Using tocolysis in pregnant women with symptomatic placenta praevia does not significantly improve prenatal, perinatal, neonatal and maternal outcomes: a systematic review and meta-analysis

Systematic Reviews ◽

10.1186/s13643-018-0923-2 ◽

2018 ◽

Vol 7 (1) ◽

Cited By ~ 2

Author(s):

Frederick Morfaw ◽

Mercy Fundoh ◽

Jessica Bartoszko ◽

Lawrence Mbuagbaw ◽

Lehana Thabane

Keyword(s):

Systematic Review ◽

Pregnant Women ◽

Meta Analysis ◽

Placenta Praevia ◽

Maternal Outcomes

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Obstructed labor and its association with adverse feto-maternal outcome in Ethiopia: a protocol for a systematic review and meta-analysis

Systematic Reviews ◽

10.1186/s13643-021-01611-x ◽

2021 ◽

Vol 10 (1) ◽

Author(s):

Yordanos Gizachew Yeshitila ◽

Melaku Desta ◽

Abraham Kebede

Keyword(s):

Systematic Review ◽

Obstetric Fistula ◽

Statistical Tests ◽

Meta Analysis ◽

Relevant Literature ◽

Near Miss ◽

Cochrane Library ◽

Maternal Outcomes ◽

Obstructed Labor ◽

Middle Income

Abstract Background Obstructed labor accounted for 22% of obstetrical complications and 9% of all maternal deaths in low- and middle-income countries. Even though there are separate studies regarding obstructed labor and its complication in Ethiopia, their results are inconsistent. The objectives of this review will be to estimate the pooled the prevalence of obstructed labor and to identify adverse feto-maternal outcomes associated with obstructed labor in Ethiopia. Methods Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline will be followed to conduct this systematic review and meta-analysis. The databases we will search will be PubMed, Cochrane Library, Google Scholar, CINAHL, African Journals Online, Dimensions, and Summon per country online databases. To search the relevant literature, we will use the following key search terms: “prevalence,” “adverse outcome,” “obstructed labour,” “maternal near miss,” “neonatal near miss,” “perinatal outcome,” “cesarean section,” “obstetric fistula,” “uterine rupture,” and “Ethiopia.” Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument will be used for evaluating the quality of the studies. Appropriate statistical tests will be conducted to quantify the between studies heterogeneity and for the assessment of publication bias. We will check individual study influence analysis and also do subgroup analysis. The STATA version 15 will be used for statistical analysis. Discussion Our systematic review and meta-analysis will provide the pooled prevalence of obstructed labor and its association with adverse feto-maternal outcomes in Ethiopia. The finding of this study will be helpful to design appropriate preventive and promotive strategies for reducing of obstructed labor-related maternal mortality. Systematic review registration PROSPERO CRD42020196153.

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Impact of point-of-care diagnostics on maternal outcomes in HIV-infected women: systematic review and meta-analysis protocol

BMJ Open ◽

10.1136/bmjopen-2015-008002 ◽

2016 ◽

Vol 6 (1) ◽

pp. e008002 ◽

Cited By ~ 3

Author(s):

T P Mashamba-Thompson ◽

B Sartorius ◽

L Thabane ◽

C X Shi ◽

P K Drain

Keyword(s):

Systematic Review ◽

Point Of Care ◽

Meta Analysis ◽

Maternal Outcomes ◽

Point Of Care Diagnostics ◽

Analysis Protocol

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Maternal Hemoglobin Concentrations Across Pregnancy and Maternal and Child Health: A Systematic Review and Meta-analysis (P11-033-19)

Current Developments in Nutrition ◽

10.1093/cdn/nzz048.p11-033-19 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

Author(s):

Melissa Fox Young ◽

Brietta Oaks ◽

Sonia Tandon ◽

Reynaldo Martorell ◽

Kathryn Dewey ◽

...

Keyword(s):

Systematic Review ◽

Child Health ◽

Health Outcomes ◽

Gestational Age ◽

Small For Gestational Age ◽

Post Partum ◽

Meta Analysis ◽

Cochrane Review ◽

World Health ◽

Maternal Outcomes

Abstract Objectives Maternal anemia is a well-recognized global health problem; however, there remain questions on specific hemoglobin thresholds that predict health risk or protection for mother and child. Our objective was to conduct a systematic review and meta-analysis to examine the associations of maternal hemoglobin concentrations with a range of maternal and infant health outcomes, accounting for timing of measurement (preconception, first, second and third trimesters), etiology of anemia and cut-off category. Methods Our search strategy identified 7,677 articles. Screening and article selection was conducted using Covidence systematic review software to organize search results from PubMed and Cochrane Review. The systematic review included 272 studies and the meta-analysis included 102 studies. Results Low maternal hemoglobin (< 110 g/L) was associated with poor birth outcomes (low birth weight, OR (95%CI): 1.43 (1.31-1.55); preterm birth, 1.35 (1.25-1.46); small-for-gestational age, 1.08 (1.00-1.18); stillbirth, 1.43 (1.05-1.95); perinatal mortality, 1.73 (1.32-2.26); and neonatal mortality, 1.49 (1.19-1.87); and adverse maternal outcomes (post-partum hemorrhage, 2.17 (1.51-3.10); preeclampsia, 1.84 (1.31-2.59); and blood-transfusion, 6.57 (3.59-12.00). High maternal hemoglobin (> 130 g/L) was associated with increased odds of small-for-gestational age, 1.22 (1.08-1.37); stillbirth, 1.88 (1.21-2.91); preeclampsia, 1.48 (1.10-2.01); and gestational diabetes, 2.02 (1.63-2.50). Relationships varied by timing of measurement and cut-off category; limited data were available on anemia etiology. There were insufficient data for other maternal outcomes and long-term child health outcomes. Conclusions Current data are insufficient for determining if revisions to current hemoglobin cut-offs are required. Pooled high-quality individual-level data analyses as well as prospective cohort studies that measure hemoglobin throughout pregnancy would be valuable to inform the re-evaluation of hemoglobin cut-offs. Funding Sources This work was commissioned and financially supported by the Evidence and Programme Guidance Unit, Department of Nutrition for Health and Development of the World Health Organization (WHO), Geneva, Switzerland.

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Correlation Between Previous Caesarean Section and Adverse Maternal Outcomes Accordingly With Robson Classification: Systematic Review and Meta-Analysis

Frontiers in Medicine ◽

10.3389/fmed.2021.740000 ◽

2022 ◽

Vol 8 ◽

Author(s):

Shazia Jamshed ◽

Shuo-Chen Chien ◽

Afifa Tanweer ◽

Rahma-Novita Asdary ◽

Muhammad Hardhantyo ◽

...

Keyword(s):

Systematic Review ◽

Caesarean Section ◽

Meta Analysis ◽

Adverse Outcomes ◽

Health Concern ◽

Maternal Outcomes ◽

Russian Science ◽

Robson Classification ◽

Russian Science Citation Index ◽

Group 5

Background: The increasing rates of Caesarean section (CS) beyond the WHO standards (10–15%) pose a significant global health concern.Objective: Systematic review and meta-analysis to identify an association between CS history and maternal adverse outcomes for the subsequent pregnancy and delivery among women classified in Robson classification (RC).Search Strategy: PubMed/Medline, EbscoHost, ProQuest, Embase, Web of Science, BIOSIS, MEDLINE, and Russian Science Citation Index databases were searched from 2008 to 2018.Selection Criteria: Based on Robson classification, studies reporting one or more of the 14 adverse maternal outcomes were considered eligible for this review.Data Collection: Study design data, interventions used, CS history, and adverse maternal outcomes were extracted.Main Results: From 4,084 studies, 28 (n = 1,524,695 women) met the inclusion criteria. RC group 5 showed the highest proportion among deliveries followed by RC10, RC7, and RC8 (67.71, 32.27, 0.02, and 0.001%). Among adverse maternal outcomes, hysterectomy had the highest association after preterm delivery OR = 3.39 (95% CI 1.56–7.36), followed by Severe Maternal Outcomes OR = 2.95 (95% CI 1.00–8.67). We identified over one and a half million pregnant women, of whom the majority were found to belong to RC group 5.Conclusions: Previous CS was observed to be associated with adverse maternal outcomes for the subsequent pregnancies. CS rates need to be monitored given the prospective risks which may occur for maternal and child health in subsequent births.

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