Patient‐reported rates of postoperative neurological symptoms following regional anaesthesia in clinical research trials

Anaesthesia ◽  
2021 ◽  
Author(s):  
U. Siddiqui ◽  
F.W. Abdallah ◽  
M. M. Ahmed ◽  
J. M. Albaum ◽  
R. Brull
Keyword(s):  
Clinical Research ◽  
Regional Anaesthesia ◽  
Neurological Symptoms ◽  
Patient Reported ◽  
Clinical Research Trials

scholarly journals Patient Experience in Home Respiratory Therapies: Where We Are and Where to Go

2019 ◽  
Vol 8 (4) ◽  
pp. 555 ◽  
Author(s):  
Cátia Caneiras ◽  
Cristina Jácome ◽  
Sagrario Mayoralas-Alises ◽  
José Ramon Calvo ◽  
João Almeida Fonseca ◽  
...  
Keyword(s):  
Clinical Research ◽  
Patient Experience ◽  
Clinical Care ◽  
Research Priorities ◽  
Specific Patient ◽  
Quality Healthcare ◽  
Body Of Knowledge ◽  
Number Of Patients ◽  
Patient Reported ◽  
System Sustainability

The increasing number of patients receiving home respiratory therapy (HRT) is imposing a major impact on routine clinical care and healthcare system sustainability. The current challenge is to continue to guarantee access to HRT while maintaining the quality of care. The patient experience is a cornerstone of high-quality healthcare and an emergent area of clinical research. This review approaches the assessment of the patient experience in the context of HRT while highlighting the European contribution to this body of knowledge. This review demonstrates that research in this area is still limited, with no example of a prescription model that incorporates the patient experience as an outcome and no specific patient-reported experience measures (PREMs) available. This work also shows that Europe is leading the research on HRT provision. The development of a specific PREM and the integration of PREMs into the assessment of prescription models should be clinical research priorities in the next several years.

User-centered design principles in the development of clinical research tools

2020 ◽  
Vol 17 (6) ◽  
pp. 703-711
Author(s):  
Anita Walden ◽  
Lynsi Garvin ◽  
Michelle Smerek ◽  
Constance Johnson
Keyword(s):  
Clinical Research ◽  
Design Principles ◽  
Acceptance Testing ◽  
Small Scale ◽  
User Centered Design ◽  
Evaluation Phase ◽  
Patient Reported ◽  
Study Participants ◽  
User Centered ◽  
Research Studies

Background: Increasing and sustaining the engagement of participants in clinical research studies is a goal for clinical investigators, especially for studies that require long-term or frequent involvement of participants. Technology can be used to reduce barriers to participation by providing multiple options for clinical data entry and form submission. However, electronic systems used in clinical research studies should be user-friendly while also ensuring data quality. Directly involving study participants in evaluating the effectiveness and usability of electronic tools may promote wider adoption, maintain involvement, and increase user satisfaction of the technology. While developers of healthcare applications have incorporated user-centered designs, these methods remain uncommon in the design of clinical study tools such as patient-reported outcome surveys or electronic data capture digital health tools. Methods: Our study evaluated whether the clinical research setting may benefit from implementing user-centered design principles. Study participants were recruited to test the web-based form for the Measurement to Understand the Reclassification of Disease of Cabarrus/Kannapolis (MURDOCK) Study Community Translational Population Health Registry and Biorepository that would enable them to complete their study forms electronically. The study enrollment form collects disease history, conditions, smoking status, medications, and other information. The system was initially evaluated by the data management team through traditional user-acceptance testing methods. During the tool evaluation phase, a decision was made to incorporate a small-scale usability study to directly test the system. Results: Results showed that a majority of participants found the system easy to use. Of the eight required tasks, 75% were completed successfully. Of the 72 heuristics violated, language was the most frequent violation. Conclusion: Our study showed that user-centered usability methods can identify important issues and capture information that can enhance the participant’s experience and may improve the quality of study tools.

scholarly journals Understanding Patient Values and the Manifestations in Clinical Research with Traditional Chinese Medicine—With Practical Suggestions for Trial Design and Implementation

2013 ◽  
Vol 2013 ◽  
pp. 1-6
Author(s):  
Wei Mu ◽  
Hongcai Shang
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Clinical Research ◽  
Patient Reported Outcomes ◽  
Patient Choice ◽  
Rational Beliefs ◽  
Choice Preference ◽  
Patient Reported ◽  
Individual Participant ◽  
Patient Values

Objective. To define patient values, identify their manifestations in a randomized clinical trial, and investigate the possible implications for clinical research of traditional Chinese medicine.Methods. We categorized patient values manifestations into patient choice, preference, compliance, and patient-reported outcomes and summarized the underlying personal values through purposeful electronic searches for relevant reports. By hypothesizing a set of positive versus negative circumstances occurring in the enrollment, intervention allocation, treatment, and the follow-up stage of a trial, it is possible to discuss the potential implications of patient values manifestation on a trial with traditional Chinese medicine.Results. Patient values and its manifestations are ubiquitous in the process of clinical research with traditional Chinese medicine. These values may provide motivation for participation or engender the internal and external validity of the study.Conclusions. Trialists should attach sufficient importance to the needs and concerns of individual participant. To incorporate patient values into the design and conduct of a clinical study with traditional Chinese medicine, researchers are recommended to adopt participant-friendly design and use patient-reported outcomes, take convenience-for-patients measures, and help foster rational beliefs and behaviors of trial participants.

scholarly journals Patient-reported outcomes: A new era in clinical research

2011 ◽  
Vol 2 (4) ◽  
pp. 137 ◽  
Author(s):  
PrasannaR Deshpande ◽  
BLakshmi Sudeepthi ◽  
Surulivel Rajan ◽  
CP Abdul Nazir
Keyword(s):  
Clinical Research ◽  
Patient Reported Outcomes ◽  
New Era ◽  
Patient Reported

scholarly journals Clinical research trials using noninvasive vascular testing

1992 ◽  
Vol 15 (5) ◽  
pp. 897-904 ◽  
Author(s):  
Dennis F. Bandyk ◽  
David S. Sumner ◽  
Brian L. Thiele ◽  
James S.T. Yao
Keyword(s):  
Clinical Research ◽  
Clinical Research Trials

The Esophageal Online Patient Reported Outcomes (EsO-PRO) Questionnaire: Formal implementation and assessment of a combined clinical and research data collection tool.

2019 ◽  
Vol 37 (4_suppl) ◽  
pp. 37-37
Author(s):  
Shirley Xue Jiang ◽  
Shubhangi Shah ◽  
Elliot Charles Smith ◽  
Justine Baek ◽  
Mindy Liang ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Data Collection ◽  
Clinical Research ◽  
Demographic Data ◽  
Qualitative Assessment ◽  
Data Collection Tool ◽  
Implementation Barriers ◽  
Survey Tool ◽  
Research Survey ◽  
Patient Reported

37 Background: Systematic symptom monitoring improves quality of life, and possibly overall survival in cancer outpatients receiving chemotherapy. To reduce patient, staff, and resource burden, combining research surveys with electronic PRO assessments in a multidisciplinary academic esophageal cancer clinic may allow dual clinical-research goals to be met. Methods: EsO-PRO is a data collection tool directed at esophageal cancer outpatients created through expert feedback. Using the Canadian Institutes of Health research (CIHR) Knowledge-to-Action (KTA) framework, clinic flow and stakeholder maps were constructed. Facilitators and barriers were then identified, and responses were generated to address implementation barriers. Multiple iterations of the questionnaire were implemented; patient and clinic staff feedback was collected through key informant interviews, and major themes were described. Results: Creation of EsO-PRO included multiple validated tools: the FACT-E, modified Cancer Research UK esophageal cancer risk questionnaire, EQ5D-5L, PRO-CTCAE for common esophageal symptoms, and baseline clinico-demographic data. Four iterations of the KTA cycle for pilot implementation identified specific key facilitators (clinician champions, staff engagement, resource-integration, and clinician-researcher synergy) and barriers (familiarity with technology, survey length, and communication barriers). Qualitative assessment also identified perceived importance of questions as key to patient completion, and role delegation, staff burden, clinic flow interruption as critical issues to address. Splitting EsO-PRO into two separate visits for completion, allowing completion at home, and changing fill-in-the-blanks to check-off boxes were identified as potential solutions. Conclusions: The CIHR-KTA framework identified concrete methods for improved integration of a combined clinical-research survey tool for routine use in a multidisciplinary esophageal cancer outpatient clinic. Our process serves as an effective model for integration of innovations in multidisciplinary esophageal cancer clinics.

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