Successful treatment of a chronic oroantral fistula infected with extensively drug resistant bacteria using long‐term oesophageal tube feeding and several non‐conventional treatments in a horse

Author(s):  
JR Fletcher ◽  
KY Yuen ◽  
AJ Stewart ◽  
AC Young ◽  
JS Gibson ◽  
...  
2017 ◽  
Vol 47 (5) ◽  
pp. 319-323 ◽  
Author(s):  
P. Vassal ◽  
P. Berthelot ◽  
J.P. Chaussinand ◽  
S. Jay ◽  
J.P. de Filippis ◽  
...  

2020 ◽  
Vol 21 (16) ◽  
pp. 5773 ◽  
Author(s):  
Surajit Bhattacharjya ◽  
Suzana K. Straus

In an era where the pipeline of new antibiotic development is drying up, the continuous rise of multi-drug resistant (MDR) and extensively drug resistant (XDR) bacteria are genuine threats to human health. Although antimicrobial peptides (AMPs) may serve as promising leads against drug resistant bacteria, only a few AMPs are in advanced clinical trials. The limitations of AMPs, namely their low in vivo activity, toxicity, and poor bioavailability, need to be addressed. Here, we review engineering of frog derived short α-helical AMPs (aurein, temporins) and lipopolysaccharide (LPS) binding designed β-boomerang AMPs for further development. The discovery of novel cell selective AMPs from the human proprotein convertase furin is also discussed.


2015 ◽  
Vol 90 (3) ◽  
pp. 186-195 ◽  
Author(s):  
D. Lepelletier ◽  
P. Berthelot ◽  
J.-C. Lucet ◽  
S. Fournier ◽  
V. Jarlier ◽  
...  

2020 ◽  
Vol 50 (8) ◽  
pp. 715-722
Author(s):  
M. Colomb-Cotinat ◽  
S. Soing-Altrach ◽  
A. Leon ◽  
Y. Savitch ◽  
I. Poujol ◽  
...  

2020 ◽  
Vol 104 (4) ◽  
pp. 503-507
Author(s):  
E. Farfour ◽  
A.-G. Si Larbi ◽  
J. Couturier ◽  
M. Lecuru ◽  
J.-W. Decousser ◽  
...  

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