The group II metabotropic glutamate receptor agonist LY354740 and the D2 receptor antagonist haloperidol reduce locomotor hyperactivity but fail to rescue spatial working memory in GluA1 knockout mice

Thomas Boerner; Alexei M. Bygrave; Jingkai Chen; Anushka Fernando; Stephanie Jackson; Chris Barkus; Rolf Sprengel; Peter H. Seeburg; Paul J. Harrison; Gary Gilmour; David M. Bannerman; David J. Sanderson

doi:10.1111/ejn.13539

The group II metabotropic glutamate receptor agonist LY354740 and the D2 receptor antagonist haloperidol reduce locomotor hyperactivity but fail to rescue spatial working memory in GluA1 knockout mice

European Journal of Neuroscience ◽

10.1111/ejn.13539 ◽

2017 ◽

Vol 45 (7) ◽

pp. 912-921 ◽

Cited By ~ 5

Author(s):

Thomas Boerner ◽

Alexei M. Bygrave ◽

Jingkai Chen ◽

Anushka Fernando ◽

Stephanie Jackson ◽

...

Keyword(s):

Working Memory ◽

Receptor Antagonist ◽

Glutamate Receptor ◽

Knockout Mice ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Spatial Working Memory ◽

D2 Receptor ◽

Metabotropic Glutamate ◽

Glutamate Receptor Agonist

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Ameliorative Effect of a Hippocampal Metabotropic Glutamate– Receptor Agonist on Histamine H1 Receptor Antagonist–Induced Memory Deficit in Rats

Journal of Pharmacological Sciences ◽

10.1254/jphs.10022fp ◽

2010 ◽

Vol 113 (1) ◽

pp. 41-47 ◽

Cited By ~ 6

Author(s):

Takayoshi Masuoka ◽

Azusa Mikami ◽

Chiaki Kamei

Keyword(s):

Receptor Antagonist ◽

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Memory Deficit ◽

H1 Receptor ◽

Metabotropic Glutamate ◽

Ameliorative Effect ◽

H1 Receptor Antagonist ◽

Glutamate Receptor Agonist

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Lack of effect of LY314582 (a group 2 metabotropic glutamate receptor agonist) on phencyclidine-induced locomotor activity in metabotropic glutamate receptor 2 knockout mice

European Journal of Pharmacology ◽

10.1016/s0014-2999(00)00269-7 ◽

2000 ◽

Vol 397 (1) ◽

pp. R1-R2 ◽

Cited By ~ 76

Author(s):

Will P.J.M Spooren ◽

Fabrizio Gasparini ◽

Herman van der Putten ◽

Manuel Koller ◽

Shigetada Nakanishi ◽

...

Keyword(s):

Locomotor Activity ◽

Glutamate Receptor ◽

Knockout Mice ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Metabotropic Glutamate ◽

Group 2 ◽

Glutamate Receptor Agonist

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EFFECTS OF GROUP III METABOTROPIC GLUTAMATE RECEPTOR AGONIST ON THE MICTURITION REFLEX IN URETHANE-ANESTHETIZED RATS

10.26226/morressier.59b63e3fd462b8029238916e ◽

2017 ◽

Author(s):

Masashi Honda

Keyword(s):

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Group Iii ◽

Micturition Reflex ◽

Metabotropic Glutamate ◽

Anesthetized Rats ◽

Glutamate Receptor Agonist

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Enzymatic resolution and pharmacological activity of the enantiomers of 3,5-dihydroxyphenylglycine, a metabotropic glutamate receptor agonist

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/0960-894x(95)00013-j ◽

1995 ◽

Vol 5 (3) ◽

pp. 223-228 ◽

Cited By ~ 30

Author(s):

S. Richard Baker ◽

John Goldsworthy ◽

Raymond C. Harden ◽

Craig R. Salhoff ◽

Darryle D. Schoepp

Keyword(s):

Glutamate Receptor ◽

Pharmacological Activity ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Enzymatic Resolution ◽

Metabotropic Glutamate ◽

Glutamate Receptor Agonist

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Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death

European Journal of Pharmacology ◽

10.1016/0014-2999(94)90624-6 ◽

1994 ◽

Vol 256 (1) ◽

pp. 109-112 ◽

Cited By ~ 90

Author(s):

Valeria Bruno ◽

Agata Copani ◽

Giuseppe Battaglia ◽

Rocco Raffaele ◽

Huruiko Shinozaki ◽

...

Keyword(s):

Protective Effect ◽

Glutamate Receptor ◽

Neuronal Death ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Metabotropic Glutamate ◽

Excitotoxic Neuronal Death ◽

Glutamate Receptor Agonist

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LY379268, a potent and selective Group II metabotropic glutamate receptor agonist, is neuroprotective in gerbil global, but not focal, cerebral ischaemia

Neuroscience Letters ◽

10.1016/s0304-3940(99)00663-1 ◽

1999 ◽

Vol 273 (3) ◽

pp. 191-194 ◽

Cited By ~ 51

Author(s):

Ann Bond ◽

Nella Ragumoorthy ◽

James A. Monn ◽

Caroline A. Hicks ◽

Mark A. Ward ◽

...

Keyword(s):

Glutamate Receptor ◽

Cerebral Ischaemia ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Focal Cerebral Ischaemia ◽

Metabotropic Glutamate ◽

Group Ii ◽

Glutamate Receptor Agonist

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Potentiation of excitatory postsynaptic potentials by a metabotropic glutamate receptor agonist (1S,3R-ACPD) in frog spinal motoneurons

Brain Research ◽

10.1016/0006-8993(95)00580-j ◽

1995 ◽

Vol 689 (2) ◽

pp. 281-288 ◽

Cited By ~ 11

Author(s):

Hiroyuki Gotani ◽

Miyuki Kuno ◽

Fusao Nakamura ◽

Shiushi Matsuura

Keyword(s):

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Excitatory Postsynaptic Potentials ◽

Spinal Motoneurons ◽

Postsynaptic Potentials ◽

Metabotropic Glutamate ◽

Glutamate Receptor Agonist

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Reversal of Phencyclidine Effects by a Group II Metabotropic Glutamate Receptor Agonist in Rats

10.1126/science.281.5381.1349 ◽

1998 ◽

Vol 281 (5381) ◽

pp. 1349-1352 ◽

Cited By ~ 715

Author(s):

B. Moghaddam

Keyword(s):

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Metabotropic Glutamate ◽

Group Ii ◽

Glutamate Receptor Agonist

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A metabotropic glutamate receptor agonist DCG-IV suppresses synaptic transmission at mossy fiber pathway of the guinea pig hippocampus

Neuroscience Letters ◽

10.1016/0304-3940(96)12486-1 ◽

1996 ◽

Vol 207 (1) ◽

pp. 70-72 ◽

Cited By ~ 49

Author(s):

Masatoshi Yoshino ◽

Satsuki Sawada ◽

Chosaburo Yamamoto ◽

Haruyuki Kamiya

Keyword(s):

Guinea Pig ◽

Synaptic Transmission ◽

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Mossy Fiber ◽

Metabotropic Glutamate ◽

Glutamate Receptor Agonist ◽

Mossy Fiber Pathway

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A new metabotropic glutamate receptor agonist: Developmental change of its sensitivity to receptors in the newborn rat spinal cord

Neuroscience Letters ◽

10.1016/0304-3940(93)90402-7 ◽

1993 ◽

Vol 160 (2) ◽

pp. 156-158 ◽

Cited By ~ 23

Author(s):

M. Ishida ◽

T. Saitoh ◽

H. Shinozaki

Keyword(s):

Spinal Cord ◽

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate Receptor ◽

Developmental Change ◽

Rat Spinal Cord ◽

Newborn Rat ◽

Metabotropic Glutamate ◽

Glutamate Receptor Agonist

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