Histopathology of the Liver in Obstructive Jaundice, Examined by Aspiration Biopsy1

2009 ◽  
Vol 108 (1-2) ◽  
pp. 48-62 ◽  
Author(s):  
KAJ ROHOLM ◽  
NIELS B. KRARUP
Keyword(s):  
Obstructive Jaundice

Indications for Surgical Exploration in the Diagnosis of Intrahepatic Obstructive Jaundice

1952 ◽  
Vol 22 (2) ◽  
pp. 232-243
Author(s):  
Leonard A. Stine ◽  
Richard M. Bendix ◽  
Jerome M. Swarts
Keyword(s):  
Obstructive Jaundice ◽  
Surgical Exploration

Impaired Fibrinolysis in Obstructive Jaundice - Evidence from Clinical and Experimental Studies

1988 ◽  
Vol 60 (01) ◽  
pp. 025-029 ◽  
Author(s):  
M Colucci ◽  
D F Altomare ◽  
G Chetta ◽  
R Triggiani ◽  
L G Cavallo ◽  
...  
Keyword(s):  
Renal Failure ◽  
Bile Duct ◽  
Obstructive Jaundice ◽  
Plasminogen Activator ◽  
Fibrinolytic Activity ◽  
Experimental Studies ◽  
Plasminogen Activator Inhibitor ◽  
Venous Stasis ◽  
Microvascular Thrombosis ◽  
Duct Ligation

SummaryMicrovascular thrombosis is considered an important pathogenetic factor in renal failure associated with obstructive jaundice but the mechanisms leading to fibrin deposition are still unknown. The plasma levels of plasminogen activator inhibitor (PAI) in 29 patients with obstructive jaundice were found significantly increased as compared to 20 nonjaundiced patients. Fibrin autography of plasma supplemented with tissue plasminogen activator (t-PA) revealed that in icteric samples most of the added activator migrated with an apparent Mr of 100 kDa, corresponding to t-PA-PAI complex, whereas in control samples virtually all t-PA migrated as free enzyme. PAI activity detected in icteric samples is similar to the endothelial type PAI since it is neutralized by a monoclonal antibody against PAI-1.Venous stasis in jaundiced patients was neither associated with an increase in blood fibrinolytic activity nor with a decrease in PAI activity. Immunologic assay showed that t-PA release was impaired in 3 out of 4 patients. In controls, venous occlusion induced an increase in both fibrinolytic activity and t-PA antigen and a reduction in PAI activity. Bile duct recanalization in jaundiced patients subjected to surgery was accompanied by a decrease in plasma PAI activity which paralleled the decrease in serum bilirubin levels. In nonjaundiced patients, surgical treatment did not cause significant changes in either parameter. Rabbits made icteric by bile duct ligation showed an early and progressive increase in plasma PAI activity indicating that obstructive jaundice itself causes the elevation of circulating PAI. It is concluded that obstructive jaundice is associated with a severe impairment of fibrinolysis which might contribute to microvascular thrombosis and renal failure.

Tuberculous Abscess of the Pancreas Presenting as Obstructive Jaundice: A Case Report

2002 ◽  
Vol 46 (6) ◽  
pp. 593 ◽  
Author(s):  
Dong Kyun Yoo ◽  
June Sik Cho ◽  
Kyung Sook Shin ◽  
Dae Young Kang
Keyword(s):  
Case Report ◽  
Obstructive Jaundice ◽  
Tuberculous Abscess

Cytochrome Oxidase Activity at The Hepatic Parenchyma Different Periods of Ischemia and Obstructive Jaundice

2019 ◽  
Vol 9 (5) ◽  
pp. p8944
Author(s):  
Askarov Tahir Askarovich ◽  
Akhmedov Mirhalil Dzhalilovich ◽  
Fayziev Yokub Nishanovic ◽  
Ashurmetov Ahmadjon Makhamadjonovich ◽  
Dalimov Kenjabek Sabutaevich ◽  
...  
Keyword(s):  
Obstructive Jaundice ◽  
Cytochrome Oxidase ◽  
Oxidase Activity ◽  
Hepatic Parenchyma ◽  
Cytochrome Oxidase Activity

scholarly journals Pancreatic Non-Hodgkin Lymphoma, a rare cause for obstructive jaundice. A Case reports

2021 ◽  
Vol 78 ◽  
pp. 369-371
Author(s):  
Pragalathan B. ◽  
Indranath K. ◽  
Jenil A.A. ◽  
Gobishangar S.
Keyword(s):  
Obstructive Jaundice ◽  
Hodgkin Lymphoma ◽  
Case Reports ◽  
Non Hodgkin Lymphoma
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