Evaluation of atherosclerosis-associated factors and pulse wave velocity for predicting cerebral infarction: a hospital-based, case?control study in Japan

2007 ◽  
Vol 37 (3) ◽  
pp. 161-167 ◽  
Author(s):  
H. Yokokawa ◽  
A. Goto ◽  
K. Watanabe ◽  
S. Yasumura
Keyword(s):  
Pulse Wave Velocity ◽  
Cerebral Infarction ◽  
Wave Velocity ◽  
Associated Factors ◽  
Pulse Wave ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Gut microbiota composition and arterial stiffness measured by pulse wave velocity: case–control study protocol (MIVAS study)

BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e038933
Author(s):  
Rita Salvado ◽  
Sandra Santos-Minguez ◽  
Cristina Agudo-Conde ◽  
Cristina Lugones-Sanchez ◽  
Angela Cabo-Laso ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Gut Microbiota ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Intestinal Microbiota ◽  
Pulse Wave ◽  
Case Control Study ◽  
Case Control ◽  
Microbiota Composition ◽  
Control Study

IntroductionIntestinal microbiota is arising as a new element in the physiopathology of cardiovascular diseases. A healthy microbiota includes a balanced representation of bacteria with health promotion functions (symbiotes). The aim of this study is to analyse the relationship between intestinal microbiota composition and arterial stiffness.Methods and analysisAn observational case—control study will be developed. Cases will be defined by the presence of at least one of the following: carotid-femoral pulse wave velocity (cf-PWV), Cardio-Ankle Vascular Index (CAVI), brachial ankle pulse wave velocity (ba or ba-PWV) above the 90th percentile, for age and sex, of the reference population. Controls will be selected from the same population as cases. The study will be developed in Primary Healthcare Centres. We will select 500 subjects (250 cases and 250 controls), between 45 and 74 years of age. Cases will be selected from a database that combines data from EVA study (Spain) and Guimarães/Vizela study (Portugal). Measurements: cf-PWV will be measured using the SphygmoCor system, CAVI, ba-PWV and Ankle-Brachial Index will be determined using VaSera device. Gut microbiome composition in faecal samples will be determined by 16S ribosomal RNA sequencing. Lifestyle will be assessed by food frequency questionnaire, adherence to the Mediterranean diet and IPAQ (International Physical Activity Questionnaire). Body composition will be evaluated by bioimpedance.Ethics and disseminationThe study has been approved by ‘Committee of ethics of research with medicines of the health area of Salamanca’ on 14 December 2018 (cod. 2018-11-136) and the ’Ethics committee for health of Guimaraes’ (Portugal) on 15 October 2019 (ref: 67/2019). All study participants will sign an informed consent form agreeing to participate in the study, in compliance with the Declaration of Helsinki and the WHO standards for observational studies. The results of this study will allow a better description of gut microbiota in patients with arterial stiffness.Trial registration detailsClinicalTrials.gov, identifier NCT03900338

326 BRACHIAL ANKLE PULSE WAVE VELOCITY IN WELL CONTROLLED RHEUMATOID ARTHRITIS PATIENTS, CASE CONTROL STUDY

2012 ◽  
Vol 30 ◽  
pp. e95
Author(s):  
Bae Keun Kim ◽  
Jae Bum Jun ◽  
Yoon Kyung Sung ◽  
Young-Hyo Lim ◽  
Bo Youl Choi ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

Thyroid cancer and its associated factors: A population‐based case‐control study

2021 ◽  
Author(s):  
Mohammad Taher Parad ◽  
Mohammad Fararouei ◽  
Ali Reza Mirahmadizadeh ◽  
Sima Afrashteh
Keyword(s):  
Thyroid Cancer ◽  
Associated Factors ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Control Study

scholarly journals Cerebral infarction in advanced non-small cell lung cancer: a case control study

BMC Cancer ◽  
2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Motoyasu Kato ◽  
Takehito Shukuya ◽  
Keita Mori ◽  
Ryota Kanemaru ◽  
Yuichiro Honma ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cerebral Infarction ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Small Cell ◽  
Small Cell Lung ◽  
Control Study

scholarly journals Association between CTSS gene polymorphism and the risk of acute atherosclerotic cerebral infarction in Chinese population: a case–control study

2018 ◽  
Vol 38 (6) ◽  
Author(s):  
Lian Luo ◽  
Mingli Zhu ◽  
Jiajun Zhou
Keyword(s):  
Cerebral Infarction ◽  
Case Control Study ◽  
Case Control ◽  
Cathepsin S ◽  
Control Group ◽  
Study Group ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Independent Risk Factors ◽  
Control Study

Objective: To investigate the association between the gene polymorphisms of rs774320676, rs768437857, rs928508030, and rs2275235 loci of Cathepsin S (CTSS) and risk of acute atherosclerotic cerebral infarction. Methods: A total of 315 patients with acute atherosclerotic cerebral infarction (study group) and 220 healthy subjects (control group) were enrolled in the present study. The genetic polymorphism of rs774320676, rs768437857, rs928508030, and rs2275235 loci of CTSS of subjects was analyzed by PCR-Sanger sequencing. Results: The proportion of carriers with mutant T allele at rs774320676 locus and mutant G allele at rs928508030 locus of CTSS in study group was significantly higher than the proportion in control group (P=0.000, adjusted odds ratio (OR) = 1.332, 95% confidence interval (CI) = 1.200–1.460; P<0.001, adjusted OR = 1.185, 95% CI = 1.055–1.314; P=0.002). The T allele at rs774320676 locus and the G allele at rs928508030 locus of CTSS were independent risk factors for acute atherosclerotic cerebral infarction (OR = 2.534, 95% CI = 1.020–4.652, P=0.006; OR = 2.016, 95% CI = 1.031–4.385, P=0.031). Conclusion: The single nucleotide polymorphisms (SNPs) of rs774320676 and rs928508030 of CTSS gene were related with risk for acute atherosclerotic cerebral infarction. The T allele at rs774320676 locus and G allele at rs928508030 locus of CTSS were genetic susceptibility genes of acute atherosclerotic cerebral infarction.

scholarly journals Evaluación de disfunción autonómica en pacientes con insuficiencia renal crónica en programa de hemodiálisis.

2013 ◽  
Vol 9 (3) ◽  
pp. 98
Author(s):  
Rafael CONTRERAS RIOS ◽  
Abdías HURTADO ARESTEGUI
Keyword(s):  
Heart Rate ◽  
Autonomic Dysfunction ◽  
Associated Factors ◽  
Case Control Study ◽  
Hemodialysis Patients ◽  
Case Control ◽  
Control Group ◽  
Deep Breathing ◽  
Program Material ◽  
Control Study

Objective: To determine the frequency of autonomic dysfunction and associated factors in patients with chronic renal failure in hemodialysis program. Material and methods: A case-control study we evaluated 30 patients in hemodialysis program and equal number of healthy volunters, using the heart rate variability test during deep breathing. Results: In hemodialysis group, twenty two patients (80%) had autonomic dysfunction, 67% were asimptomatics. In control group only two patients had autonomic dysfunction (6.7%). In both groups, we found positive correlation than age with autonomic dysfunction stage. Conclusion: Autonomic dysfunction is a frequent complication in hemodialysis patients; it’s frequently asymptomatic and it has age relationship.

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