Structure-function relationship in the process of primary open-angle glaucoma - an OCT study

2007 ◽  
Vol 85 ◽  
pp. 0-0
Author(s):  
CS AJTONY ◽  
ZS BALLA ◽  
B KOVACS
Keyword(s):  
Structure Function ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Structure Function Relationship ◽  
Function Relationship

scholarly journals Structure–function Relationship and Vision-related Quality of Life in Glaucoma Secondary to Anterior Uveitis: Comparison with Open Angle Glaucoma

2021 ◽  
Author(s):  
Jin A Choi ◽  
Ji-Young Lee ◽  
Tae Yoon La ◽  
Jin-Ho Kim
Keyword(s):  
Quality Of Life ◽  
Structure Function ◽  
Visual Function ◽  
Open Angle Glaucoma ◽  
Composite Score ◽  
Open Angle ◽  
Structure Function Relationship ◽  
Related Quality ◽  
Function Relationship

Abstract Uveitis is the most common inflammatory ocular disorder and frequently complicated by glaucoma, which is an important cause of irreversible sight loss. Inflammatory nature of the disease and widely fluctuating of intraocular pressure may affect visual function in patients with uveitis complicated by glaucoma. Therefore, we investigated the structure − function relationship and vision-related quality of life (VR-QoL) in 69 patients with uveitic glaucoma (UG), compared with 138 patients with primary open-angle glaucoma (OAG) using 25-item National Eye Institute Visual Function Questionnaire (VFQ-25). In a generalized linear model including age and corresponding structural metrics, the UG eyes had significantly lower mean deviation (MD) of the whole visual field (VF) and superior VF than the OAG eyes (p = 0.012 and 0.040). Patients with UG showed significantly lower composite score and 5 subscales of the VFQ-25, compared with those with OAG (p < 0.05, for all). In the OAG group, the composite score showed strongest associations with the whole binocular integrated VF (β = 1.156, p < 0.001), whereas in the UG group, a significant association was seen only with the inferior VF of the affected eye (β = 0.747, p = 0.005). In conclusion, eyes with UG exhibited a distinctive structure–function relationship and worse VR-QoL that differentiated them from OAG eyes.

Comparison of the structure–function relationship between compass microperimetry and Humphrey field analyser in myopic open-angle glaucoma eyes

2020 ◽  
pp. bjophthalmol-2020-317850
Author(s):  
Joong Won Shin ◽  
Min Kyung Song ◽  
Hun Jae Won ◽  
Younhye Jo ◽  
Michael S Kook
Keyword(s):  
Structure Function ◽  
Open Angle Glaucoma ◽  
General Structure ◽  
Random Order ◽  
Retinal Nerve Fibre Layer ◽  
Open Angle ◽  
Field Analyser ◽  
Structure Function Relationship ◽  
Nerve Fibre Layer ◽  
Function Relationship

Background/aimsTo compare the structure–function relationship between compass microperimetry (CMP; CenterVue, Padova, Italy) and Humphrey field analyser (HFA; Carl Zeiss Meditec, Dublin, California, USA) in open-angle glaucoma (OAG) eyes with myopia.MethodsCircumpapillary retinal nerve fibre layer thickness (cpRNFLT) and visual field (VF) mean sensitivity (MS) were obtained in 90 OAG subjects using the optical coherence tomography, CMP and HFA in a random order. The global and sectoral structure–function relationships between the cpRNFLT and VFMS were assessed with different VF devices (CMP vs HHA) in OAG eyes with and without myopia.ResultsOverall, the global and regional structure–function relationships between the two devices did not show significant differences except for the superotemporal sector. In the myopic subgroup, the global association between the average cpRNFLT and VFMSCMP was significantly stronger than that between the average cpRNFLT and VFMSHFA (r=0.806 vs. 0.720, p=0.035). The presence of myopia and higher global cpRNFLT were significantly associated with the greater global VFMS differences between the two devices (p<0.05).ConclusionIn general, structure–function relationship is similar between CMP and HFA in OAG eyes. However, the global structure–function relationship is significantly stronger with CMP than with HFA in OAG eyes with myopia.

scholarly journals Focal Structure–Function Relationships in Primary Open-Angle Glaucoma Using OCT and OCT-A Measurements

2020 ◽  
Vol 61 (14) ◽  
pp. 33
Author(s):  
Damon Wong ◽  
Jacqueline Chua ◽  
Emily Lin ◽  
Bingyao Tan ◽  
Xinwen Yao ◽  
...  
Keyword(s):  
Structure Function ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle

Structure-Function Correlation Using Confocal Laser Ophthalmoscope in Primary Open-Angle Glaucoma and Pseudoexfoliative Glaucoma

2016 ◽  
Vol 25 (4) ◽  
pp. 377-382
Author(s):  
Theofanis Pappas ◽  
Panayiota Founti ◽  
Xiang Jun Yin ◽  
Archimidis Koskosas ◽  
Eleftherios Anastasopoulos ◽  
...  
Keyword(s):  
Structure Function ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Confocal Laser ◽  
Open Angle ◽  
Pseudoexfoliative Glaucoma ◽  
Function Correlation

scholarly journals Combining OCT and OCTA for Focal Structure–Function Modeling in Early Primary Open-Angle Glaucoma

2021 ◽  
Vol 62 (15) ◽  
pp. 8
Author(s):  
Damon Wong ◽  
Jacqueline Chua ◽  
Bingyao Tan ◽  
Xinwen Yao ◽  
Rachel Chong ◽  
...  
Keyword(s):  
Structure Function ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Early Primary

Clinical efficacy of osteopathic correction in the complex treatment of patients with unoperated open-angle glaucoma

2020 ◽  
pp. 97-105
Author(s):  
E. N. Simakova ◽  
O. V. Stenkova
Keyword(s):  
Intraocular Pressure ◽  
Drug Therapy ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Randomized Study ◽  
Main Group ◽  
Control Group ◽  
Open Angle ◽  
Complex Treatment ◽  
Hypotensive Drug

Introduction. Glaucoma is one of the most significant eye diseases. It is often diagnosed, not always amenable to therapy, and can lead to a complete loss of visual functions. In recent years, the method of osteopathic correction has become widespread as one of the effective methods of treatment and rehabilitation of patients with pathologies of various body systems. In the pathogenesis of glaucoma, it is customary to distinguish a dystrophic concept, which considers primary open-angle glaucoma as a result of dystrophic changes in the connective tissue, as well as in the endothelial lining of the trabeculae and Schlemm′s canal, especially destructive changes in mitochondria and the alteration of their functional activity. A vascular concept is also distinguished. According to this concept, the central link in the pathogenesis of glaucoma is circulatory disorder in the ciliary vessels, ocular artery, and major vessels of the head and neck, it can be assumed that osteopathic correction in the treatment of patients with open-angle glaucoma will be pathogenetically substantiated and will have a positive effect on intraocular pressure and trophicity of the optic nerve. The goal of research — to study the influence of in osteopathic correction on the nature of unoperated glaucoma (stage IIA) and to substantiate the possibility of using osteopathic correction in the complex treatment of patients with this pathology.Materials and methods. A prospective controlled randomized study was conducted at 52 city polyclinics, branch 3, Moscow, from January 2018 to January 2019. 40 patients (70 eyes) aged 50 to 75 years with primary open-angle glaucoma IIA stage were examined. At this stage of the disease, patients most often seek medical care and the issue of conservative management is primarily considered. All patients were divided into two groups of 20 people: the main group and the control group. The treatment in the main group included hypotensive drug therapy and osteopathic correction. Patients of the control group received only drug therapy. All patients underwent ophthalmic (visometry, tonometry, perimetry) and osteopathic examination twice: before the treatment and after 3 months.Results. For patients with primary open-angle IIA non-operated glaucoma, regional (most often regions of the head, neck, dura mater) and local (abdominal diaphragm, iliac bones, hip and knee joints) somatic dysfunctions were the most typical. In the main group a statistically significant decrease in the frequency and severity of dysfunctions at all levels was stated. Also, in patients receiving osteopathic correction, a significant decrease in the level of intraocular pressure and perimetric indices was noted. In patients of the control group, no reliable changes in these indicators were obtained.Conclusion. The results obtained indicate that osteopathic correction is clinically effective in the complex treatment of patients with primary open-angle II A glaucoma.

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