The effect of sodium lauryl sulphate, triclosan and zinc on the permeability of normal oral mucosa

Oral Diseases ◽  
2008 ◽  
Vol 6 (2) ◽  
pp. 118-123 ◽  
Author(s):  
CM Healy ◽  
AT Cruchley ◽  
MH Thornhill ◽  
DM Williams
Keyword(s):  
Oral Mucosa ◽  
Sodium Lauryl Sulphate ◽  
Normal Oral Mucosa

Association of normal oral mucosa with DNA of the main types of oncogenic viruses

2020 ◽  
pp. 60-63
Author(s):  
S.I. Kutukova ◽  
A.B. Chukhlovin ◽  
A.I. Yaremenko ◽  
Yu.V. Ivaskova ◽  
A.Ya. Razumova ◽  
...  
Keyword(s):  
Oral Mucosa ◽  
Epstein Barr Virus ◽  
Oncogenic Viruses ◽  
Viral Dna ◽  
Dna Viruses ◽  
Normal Oral Mucosa ◽  
Barr Virus ◽  
Ebv Dna ◽  
Epstein Barr ◽  
Hpv 18

The aim of the study was to assess the prevalence of DNA viruses (HSV I and II, CMV, EBV, HPV6.11, HPV16 and HPV18) in the native oral mucosa of healthy volunteers (n=50; 30 men (60.0%), 20 women (40.0%); 25—74 years, median age — 55.0 years (95% CI 47.60-56.76)). All samples of the normal oral mucosa were detected by real-time PCR to detect viral DNA. The majority of the examined — 76% (33/50) — revealed the DNA: one type of viral DNA in 17 (38.00%) of the examined, a combination of the two types in 14 (28.00%). In the normal oral mucosa, DNA of Epstein-Barr virus was significantly more often detected: 15 (30.00%) (p = 0.0276) and human papilloma viruses 27 (54.00%) (p <0.0001), especially HPV-18 (24 (48.00%)): mono-association in 9 (18.00%) examined and in 7 (14.00%) in combination with EBV DNA (p = 0.0253).

scholarly journals Low prevalence of high risk human papillomavirus in normal oral mucosa by hybrid capture 2

2008 ◽  
Vol 39 (1) ◽  
Author(s):  
Maria del Refugio González-Losa ◽  
Luis Manzano-Cabrera ◽  
Florencio Rueda-Gordillo ◽  
Sandra E. Hernández-Solís ◽  
Marylin Puerto-Solís
Keyword(s):  
Human Papillomavirus ◽  
High Risk ◽  
Oral Mucosa ◽  
Hybrid Capture ◽  
Normal Oral Mucosa ◽  
Hybrid Capture 2 ◽  
Low Prevalence

scholarly journals p53 immunohistochemical staining patterns in oral squamous cell carcinoma

2016 ◽  
Vol 6 (12) ◽  
pp. 1013-1017
Author(s):  
G Dundy ◽  
H Kumar ◽  
A Singh ◽  
A Chandarakant
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Oral Mucosa ◽  
Squamous Cell ◽  
P53 Protein ◽  
P Value ◽  
P53 Expression ◽  
Normal Oral Mucosa ◽  
Significant Difference

Background: Mutation of p53 gene is one of the most common events in oral carcinogenesis. Accumulation of p53 protein has also been detected in premalignant lesions.Materials and Methods:  This study included 40 biopsy samples, which were received in department of pathology, Sarojini Naidu Medical College, Agra, to ascertain p53 expression by immunohistochemically, in patients with oral squamous cell carcinomas and to correlate its expression with histological grade, different sites in oral cavity and tobacco intake/smoking habits.Results: Out of 40 biopsies of oral mucosa, 03 showed normal oral mucosa and 37 were diagnosed as squamous cell carcinoma (SCC), most patients were in 5th and 6th decade and majority (86.5%) of oral SCC were males with buccal mucosa being the most common site. There was a statistically significant difference in p53 expression between oral SCC and normal oral mucosa (p value <0.05). Of total 37 cases, 12 cases were well differentiated type, 16 moderately differentiated and 09 of poorly differentiated type of SCC. In each category, about two thirds were positive for p53 staining. Out of total 37 cases of oral SCC, 64.9% were positive and 35.1% were negative for p53 expression, 34 cases had positive history of tobacco intake/smoking habits, of which 23 cases were positive while 11 cases were negative for p53 staining.Conclusion: Abnormal p53 protein was detected in 64.9% of oral squamous cell carcinoma, but not in normal oral mucosa. p53 expression was associated with malignant transformation of oral mucosa. 

scholarly journals High-risk human papilloma virus in archival tissues of oral pathosis and normal oral mucosa

2015 ◽  
Vol 6 (2) ◽  
pp. 148 ◽  
Author(s):  
RUma Devi ◽  
Raghu Dhanapal ◽  
K Ranganathan ◽  
Paturu Kondaiah ◽  
Elizabeth Joshua ◽  
...  
Keyword(s):  
High Risk ◽  
Human Papilloma Virus ◽  
Oral Mucosa ◽  
Papilloma Virus ◽  
Normal Oral Mucosa

The first normal oral mucosa epithelium in which ?-glutamyl transpeptidase activity has been detected

1992 ◽  
Vol 24 (12) ◽  
pp. 964-968 ◽  
Author(s):  
A. E. Schwint ◽  
A. M. Collet ◽  
A. E. Mendez ◽  
R. L. Cabrini ◽  
M. E. Itoiz
Keyword(s):  
Oral Mucosa ◽  
Normal Oral Mucosa ◽  
Glutamyl Transpeptidase ◽  
Mucosa Epithelium

The concentration values of aluminum in normal oral mucosa measured by the pixe method

2005 ◽  
Vol 34 ◽  
pp. 162-163
Author(s):  
Y. Sugiyama ◽  
S. Ishibashi ◽  
H. Furuuchi ◽  
H. Iwabuchi ◽  
T. Sawada ◽  
...  
Keyword(s):  
Oral Mucosa ◽  
Normal Oral Mucosa ◽  
Pixe Method

Automated characterization of sub-epithelial connective tissue cells of normal oral mucosa: Bayesian approach

2010 ◽  
Author(s):  
M Muthu Rama Krishnan ◽  
Pratik Shah ◽  
Madhumala Ghosh ◽  
Mousumi Pal ◽  
Chandan Chakraborty ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Oral Mucosa ◽  
Bayesian Approach ◽  
Normal Oral Mucosa ◽  
Tissue Cells

scholarly journals Comparison of Immunohistochemical Expression of Antiapoptotic Protein Survivin in Normal Oral Mucosa, Oral Leukoplakia, and Oral Squamous Cell Carcinoma

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Amita Negi ◽  
Abhiney Puri ◽  
Rakhi Gupta ◽  
Rajat Nangia ◽  
Alisha Sachdeva ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Oral Mucosa ◽  
Squamous Cell ◽  
Oral Leukoplakia ◽  
Immunohistochemical Expression ◽  
Antiapoptotic Protein ◽  
Normal Oral Mucosa ◽  
Survivin Protein

Background. Oral squamous cell carcinoma is the sixth most frequent malignant tumor worldwide and the third most common cancers in developing countries. Oral leukoplakia is the best-known precursor lesion of oral squamous cell carcinoma. The aim of the present study was to compare immunohistochemical expression of antiapoptotic protein survivin in normal oral mucosa, oral leukoplakia, and oral squamous cell carcinoma. Method. Total 45 specimens of formalin fixed paraffin embedded tissue blocks, 15 in each of the following: normal oral mucosa, leukoplakia, and oral squamous cell carcinoma were used for the study. Immunohistochemical reaction for survivin protein was performed for the 4 µm thick histological sections taken on positively charged slides. Results. 20% normal mucosa cases, 53.33% cases of leukoplakia, and 80% of oral squamous cell carcinoma were found out to be survivin positive. One way ANOVA test indicated statistically significant difference of survivin expression between the three different groups p<0.001. Conclusion. A high incidence of survivin protein expression in oral epithelial dysplasia and squamous cell carcinoma samples indicate that survivin protein expression may be an early event in initiation and progression of oral squamous cell carcinoma.

Sign in / Sign up

Export Citation Format

Share Document