scholarly journals Quantifying the abnormal macular pigment distribution in macular telangiectasia type 2

2008 ◽  
Vol 86 ◽  
pp. 0-0
Author(s):  
LP VAN DER VEEN ◽  
P CHARBEL-ISSA ◽  
A STIJFS ◽  
FG HOLZ ◽  
HPN SCHOLL ◽  
...  
Keyword(s):  
Macular Pigment ◽  
Macular Telangiectasia ◽  
Pigment Distribution ◽  
Macular Telangiectasia Type 2

scholarly journals Macular Pigment Distribution as Prognostic Marker for Disease Progression in Macular Telangiectasia Type 2

2018 ◽  
Vol 194 ◽  
pp. 163-169 ◽  
Author(s):  
Simone Müller ◽  
Peter Charbel Issa ◽  
Tjebo F.C. Heeren ◽  
Sarah Thiele ◽  
Frank G. Holz ◽  
...  
Keyword(s):  
Disease Progression ◽  
Prognostic Marker ◽  
Macular Pigment ◽  
Macular Telangiectasia ◽  
Pigment Distribution ◽  
Macular Telangiectasia Type 2

scholarly journals MACULAR PIGMENT DISTRIBUTION RESPONSES TO HIGH-DOSE ZEAXANTHIN SUPPLEMENTATION IN PATIENTS WITH MACULAR TELANGIECTASIA TYPE 2

Retina ◽  
2017 ◽  
Vol 37 (12) ◽  
pp. 2238-2247 ◽  
Author(s):  
Rene Y. Choi ◽  
Aruna Gorusupudi ◽  
Kimberley Wegner ◽  
Mohsen Sharifzadeh ◽  
Werner Gellermann ◽  
...  
Keyword(s):  
Macular Pigment ◽  
High Dose ◽  
Macular Telangiectasia ◽  
Pigment Distribution ◽  
Macular Telangiectasia Type 2

IDIOPATHIC MACULAR TELANGIECTASIA TYPE 2: DISTRIBUTION OF MACULAR PIGMENT AND FUNCTIONAL INVESTIGATIONS

Retina ◽  
2010 ◽  
Vol 30 (4) ◽  
pp. 586-595 ◽  
Author(s):  
MEIKE B. ZEIMER ◽  
BJÖRN PADGE ◽  
BRITTA HEIMES ◽  
DANIEL PAULEIKHOFF
Keyword(s):  
Macular Pigment ◽  
Macular Telangiectasia ◽  
Macular Telangiectasia Type 2 ◽  
Idiopathic Macular Telangiectasia

Morphological characteristics preceding exudative neovascularisation secondary to macular telangiectasia type 2

2021 ◽  
pp. bjophthalmol-2020-318470
Author(s):  
Kristina Hess ◽  
Peter Charbel Issa ◽  
Frank G Holz ◽  
Simone Tzaridis
Keyword(s):  
De Novo ◽  
Morphological Changes ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Morphological Characteristics ◽  
Macular Pigment ◽  
Fundus Photography ◽  
Macular Telangiectasia ◽  
Macular Telangiectasia Type 2

AimsTo identify morphological characteristics preceding the development of exudative neovascularisation secondary to Macular Telangiectasia type 2 (MacTel) using multimodal retinal imaging.MethodsIn this retrospective study, eyes with a minimum observation period of 6 months prior to the de novo diagnosis of an exudative neovascularisation secondary to MacTel were analysed. Morphological changes preceding the formation of neovascularisation were evaluated using colour fundus photography, infrared imaging, fluorescein angiography, macular pigment measurement and optical coherence tomography (OCT). OCT-angiography (OCT-A) images were additionally available in a subset of patients.ResultsTwenty eyes from 20 patients were examined over a median period of 17 months (range: 6–100 months). Eyes were characterised by an accelerated progression of ellipsoid zone loss (median of 0.013 mm2/month), increased thickness of the temporal parafovea and hyper-reflective lesions on OCT. The latter underwent morphological changes preceding the development of exudative neovascularisation, including an increase in size and density, and expansion to outer retinal layers and the retinal pigment epithelium. All eyes showed a foveal depletion of macular pigment. On OCT-A, a focal increase in blood flow was observed at the level of the outer retina/choriocapillaris, and retinal–retinal and retinal–choroidal anastomoses preceded the formation of exudative neovascularisation.ConclusionsMultimodal imaging allows the identification of prognostic morphological features preceding the formation of exudative neovascularisation in MacTel. Eyes exhibiting these characteristics should be monitored closely and patients should be alert for emergent symptoms in order to detect and treat neovascularisation early and, thereby, prevent irreversible visual loss.

Quantification of reduced macular pigment optical density in the central retina in macular telangiectasia type 2

2009 ◽  
Vol 89 (1) ◽  
pp. 25-31 ◽  
Author(s):  
Peter Charbel Issa ◽  
Rob L.P. van der Veen ◽  
Astrid Stijfs ◽  
Frank G. Holz ◽  
Hendrik P.N. Scholl ◽  
...  
Keyword(s):  
Optical Density ◽  
Macular Pigment ◽  
Macular Pigment Optical Density ◽  
Macular Telangiectasia ◽  
Central Retina ◽  
Macular Telangiectasia Type 2

ABNORMAL MACULAR PIGMENT DISTRIBUTION IN TYPE 2 IDIOPATHIC MACULAR TELANGIECTASIA

Retina ◽  
2008 ◽  
Vol 28 (6) ◽  
pp. 808-816 ◽  
Author(s):  
HANS-MARTIN HELB ◽  
PETER CHARBEL ISSA ◽  
ROB L. P. VAN DER VEEN ◽  
TOS T. J. M. BERENDSCHOT ◽  
HENDRIK P. N. SCHOLL ◽  
...  
Keyword(s):  
Macular Pigment ◽  
Macular Telangiectasia ◽  
Pigment Distribution ◽  
Idiopathic Macular Telangiectasia

scholarly journals Idiopathic Macular Telangiectasia Type 2 and Its Relationship with Macular Pigment Optical Density

2019 ◽  
pp. 01-12
Author(s):  
Chris Putnam
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Macular Pigment ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Macular Telangiectasia ◽  
Layer Deposition ◽  
Macular Telangiectasia Type 2 ◽  
Idiopathic Macular Telangiectasia

Idiopathic macular telangiectasia type 2 (IMT2) is a relatively uncommon clinical condition with an estimated prevalence of 1% within the general population. This condition can be challenging to precisely identify in early stages but advancements in clinical imaging to include fluorescein angiography and optical coherence tomography angiography (OCTA) can allow for timely diagnosis and prompt intervention that may leads to improved long-term clinical outcomes. Emerging literature has recognized the role of macular pigment (MP) in IMT2 in terms of Henle fiber layer deposition mechanisms and potential mitigation of inflammatory and oxidative stress. Primary care optometrists are in a unique position to facilitate early detection and manage through close evaluation and individualized lutein and zeaxanthin supplementation. Keywords: Idiopathic macular telangiectasia type 2; Macular pigment; Spectral domain optical coherence tomography angiography

Prevalence and Severity of Diabetic Retinopathy in Patients with Macular Telangiectasia type 2.

2021 ◽  
Author(s):  
Saskia HM. van Romunde ◽  
Charlotte M. van der Sommen ◽  
José P. Martinez Ciriano ◽  
Johannes R. Vingerling ◽  
Suzanne Yzer
Keyword(s):  
Diabetic Retinopathy ◽  
Macular Telangiectasia ◽  
Macular Telangiectasia Type 2
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