Prevalence and Incidence of Patients with Paroxysmal Supraventricular Tachycardia in the United States

Author(s):  
Michael Rehorn ◽  
Naomi C. Sacks ◽  
Maia R. Emden ◽  
Bridget Healey ◽  
Madison T. Preib ◽  
...  
PEDIATRICS ◽  
1972 ◽  
Vol 50 (1) ◽  
pp. 127-130
Author(s):  
Leonard M. Linde ◽  
Searle W. Turner ◽  
Shoichi Awa

The therapeutic agents that have been described will successfully convert close to 100% of all episodes of PST in children. Digoxin is the most frequently used agent for treatment of acute PST and is highly effective and safe. Recently, cardioversion and beta-adrenergic blockade are being employed more frequently, both with specific indications. Newer electrical means and new agents such as Verapamil are effective but the former are not yet widely used and the latter not yet authorized for use in the United States. Prophylaxis of recurrent episodes is usually successful with digoxin, with the addition or substitution of propranolol in certain conditions.


2020 ◽  
Vol 13 (Suppl_1) ◽  
Author(s):  
Michael Rehorn ◽  
Naomi Sacks ◽  
Madison Preib ◽  
Philip Cyr ◽  
Maia Emden ◽  
...  

Background: Paroxysmal supraventricular tachycardia (PSVT) encompasses a range of heart rhythm disorders that lead to abrupt increases in heart rate. Given its episodic nature, PSVT can be difficult to capture in a clinical setting. Therefore, estimating incidence of PSVT is challenging and thus limited data is available on the incidence of this disease. Objective: Estimate the incidence of PSVT within the United States in contemporary practice. Methods: Using claims, enrollment, and demographic data from the IBM Marketscan® Commercial Research Database (<65y) and the Medicare Limited Dataset (≥65y), individuals enrolled in health plans for at least 5 continuous years from 2008-2016 were identified. Patients having claims with a PSVT diagnosis (ICD-9: 427.0; ICD-10 I47.1) on 2+ outpatient visits, 1+ ED visit, or 1+ inpatient admission were included in the analysis. Only patients receiving an initial diagnosis of PSVT in year 5 of continuous enrollment were included in the incidence calculation in order to avoid including prevalent cases. Incidence was projected to the US population based on the 2018 US census data. Results: Among 18,057,297 patients, 86,614 met PSVT criteria. Incidence rates were higher in female and older patients. Within the 18-44y group, the incidence rate was 1.9-fold higher for females as compared to males. Overall incidence rate per 100,000 was 79.1 and 107.2 for males and females respectively (Table). Projected to the 2018 US Census, there were 305,548 incident PSVT cases in 2018. Conclusion: There were over 305,000 incident cases of PSVT in 2018 with higher rates in female and older patients. Further studies are needed to understand practice patterns in management of PSVT, given the high incidence of this disease.


2011 ◽  
Vol 34 (7) ◽  
pp. 832-836 ◽  
Author(s):  
JACK C. SALERNO ◽  
MICHELLE M. GARRISON ◽  
CINDY LARISON ◽  
STEPHEN P. SESLAR

Author(s):  
A. Hakam ◽  
J.T. Gau ◽  
M.L. Grove ◽  
B.A. Evans ◽  
M. Shuman ◽  
...  

Prostate adenocarcinoma is the most common malignant tumor of men in the United States and is the third leading cause of death in men. Despite attempts at early detection, there will be 244,000 new cases and 44,000 deaths from the disease in the United States in 1995. Therapeutic progress against this disease is hindered by an incomplete understanding of prostate epithelial cell biology, the availability of human tissues for in vitro experimentation, slow dissemination of information between prostate cancer research teams and the increasing pressure to “ stretch” research dollars at the same time staff reductions are occurring.To meet these challenges, we have used the correlative microscopy (CM) and client/server (C/S) computing to increase productivity while decreasing costs. Critical elements of our program are as follows:1) Establishing the Western Pennsylvania Genitourinary (GU) Tissue Bank which includes >100 prostates from patients with prostate adenocarcinoma as well as >20 normal prostates from transplant organ donors.


Author(s):  
Vinod K. Berry ◽  
Xiao Zhang

In recent years it became apparent that we needed to improve productivity and efficiency in the Microscopy Laboratories in GE Plastics. It was realized that digital image acquisition, archiving, processing, analysis, and transmission over a network would be the best way to achieve this goal. Also, the capabilities of quantitative image analysis, image transmission etc. available with this approach would help us to increase our efficiency. Although the advantages of digital image acquisition, processing, archiving, etc. have been described and are being practiced in many SEM, laboratories, they have not been generally applied in microscopy laboratories (TEM, Optical, SEM and others) and impact on increased productivity has not been yet exploited as well.In order to attain our objective we have acquired a SEMICAPS imaging workstation for each of the GE Plastic sites in the United States. We have integrated the workstation with the microscopes and their peripherals as shown in Figure 1.


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