Non‐native species drive biotic homogenization, but it depends on the realm, beta diversity facet and study design: a meta‐analytic systematic review

IntroductionType 2 diabetes is a global health priority. People with diabetes are more likely to experience mental health problems relative to people without diabetes. Diabetes guidelines recommend assessment of depression and diabetes distress during diabetes care. This systematic review will examine the effect of routinely assessing and addressing depression and diabetes distress using patient-reported outcome measures in improving outcomes among adults with type 2 diabetes.Methods and analysisMEDLINE, Embase, CINAHL Complete, PsycInfo, The Cochrane Library and Cochrane Central Register of Controlled Trials will be searched using a prespecified strategy using a prespecified Population, Intervention, Comparator, Outcomes, Setting and study design strategy. The date range of the search of all databases will be from inception to 3 August 2020. Randomised controlled trials, interrupted time-series studies, prospective and retrospective cohort studies, case–control studies and analytical cross-sectional studies published in peer-reviewed journals in the English language will be included. Two review authors will independently screen abstracts and full texts with disagreements resolved by a third reviewer, if required, using Covidence software. Two reviewers will undertake risk of bias assessment using checklists appropriate to study design. Data will be extracted using prespecified template. A narrative synthesis will be conducted, with a meta-analysis, if appropriate.Ethics and disseminationEthics approval is not required for this review of published studies. Presentation of results will follow the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidance. Findings will be disseminated via peer-reviewed publication and conference presentations.PROSPERO registration numberCRD42020200246.

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SARS-CoV-2 genome and antibodies in breastmilk: a systematic review and meta-analysis

Archives of Disease in Childhood - Fetal and Neonatal Edition ◽

10.1136/archdischild-2020-321074 ◽

2021 ◽

pp. fetalneonatal-2020-321074

Author(s):

Faith Zhu ◽

Carlos Zozaya ◽

Qi Zhou ◽

Charmaine De Castro ◽

Prakesh S Shah

Keyword(s):

Systematic Review ◽

Outcome Measures ◽

Study Design ◽

Web Of Science ◽

Meta Analysis ◽

Respiratory Support ◽

Common Finding ◽

Rt Pcr

ObjectiveTo systematically review and meta-analyse the rate of SARS-CoV-2 genome identification and the presence of SARS-CoV-2 antibodies in breastmilk of mothers with COVID-19.DesignA systematic review of studies published between January 2019 and October 2020 without study design or language restrictions.SettingData sourced from Ovid Embase Classic+Embase, PubMed, Web of Science, Scopus, relevant bibliographies and the John Hopkins University COVID-19 database.PatientsMothers with confirmed COVID-19 and breastmilk tested for SARS-CoV-2 by RT-PCR or for anti-SARS-CoV-2 antibodies.Main outcome measuresPresence of SARS-CoV-2 genome and antibodies in breastmilk.ResultsWe included 50 articles. Twelve out of 183 women from 48 studies were positive for SARS-CoV-2 genome in their breastmilk (pooled proportion 5% (95% CI 2% to 15%; I2=48%)). Six infants (50%) of these 12 mothers tested positive for SARS-CoV-2, with one requiring respiratory support. Sixty-one out of 89 women from 10 studies had anti-SARS-CoV-2 antibody in their breastmilk (pooled proportion 83% (95% CI 32% to 98%; I2=88%)). The predominant antibody detected was IgA.ConclusionsSARS-CoV-2 genome presence in breastmilk is uncommon and is associated with mild symptoms in infants. Anti-SARS-CoV-2 antibodies may be a more common finding. Considering the low proportion of SARS-CoV-2 genome detected in breastmilk and its lower virulence, mothers with COVID-19 should be supported to breastfeed.

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The impact of study design on schizophrenia incidence estimates: A systematic review of Northern European studies 2008–2019

Schizophrenia Research ◽

10.1016/j.schres.2021.03.017 ◽

2021 ◽

Vol 231 ◽

pp. 134-141

Author(s):

Simon J. Hogerzeil ◽

Hans W. Hoek ◽

Albert M. van Hemert

Keyword(s):

Systematic Review ◽

Study Design ◽

European Studies ◽

Northern European ◽

The Impact

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Spontaneous brain microbleeds: systematic review, subgroup analyses and standards for study design and reporting

Brain ◽

10.1093/brain/awl387 ◽

2007 ◽

Vol 130 (8) ◽

pp. 1988-2003 ◽

Cited By ~ 400

Author(s):

C. Cordonnier ◽

R. Al-Shahi Salman ◽

J. Wardlaw

Keyword(s):

Systematic Review ◽

Study Design ◽

Subgroup Analyses

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Systematic Reviews are Rarely Used to Inform Study Design - a Systematic Review and Meta-analysis

Journal of Clinical Epidemiology ◽

10.1016/j.jclinepi.2022.01.007 ◽

2022 ◽

Author(s):

Birgitte Nørgaard ◽

Eva Draborg ◽

Jane Andreasen ◽

Carsten Bogh Juhl ◽

Jennifer Yost ◽

...

Keyword(s):

Systematic Review ◽

Study Design ◽

Systematic Reviews ◽

Meta Analysis

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Return to Sport After Ankle Syndesmotic Injury: A Systematic Review

Sports Health A Multidisciplinary Approach ◽

10.1177/1941738118816282 ◽

2018 ◽

Vol 11 (2) ◽

pp. 116-122 ◽

Cited By ~ 1

Author(s):

Seline Y. Vancolen ◽

Ibrahim Nadeem ◽

Nolan S. Horner ◽

Herman Johal ◽

Bashar Alolabi ◽

...

Keyword(s):

Systematic Review ◽

Study Design ◽

Return To Sport ◽

Nonoperative Treatment ◽

High Rate ◽

Rate Of Return ◽

Syndesmotic Injury ◽

Level Of Evidence ◽

Treatment Groups ◽

Pertinent Data

Context: Ankle syndesmotic injuries present a significant challenge for athletes due to prolonged disability and recovery periods. The optimal management of these injuries and rates of return to sport in athletes remains unclear. Objective: The purpose of this study was to evaluate return to sport for athletes after ankle syndesmotic injuries. Data Source: The electronic databases MEDLINE, EMBASE, and PubMed were searched for relevant studies from database inception to January 15, 2017, and pertinent data were abstracted. Study Selection: Only studies reporting return-to-sport rates after ankle syndesmotic injuries were included. Study Design: Systematic review. Level of Evidence: Level 4. Data Extraction: Two reviewers extracted data from the included studies, which were stored in a standardized collection form (Microsoft Excel). Recorded data included demographics (eg, author, year of publication, study design), descriptive statistics (eg, patient age, percentage male, number of athletes, sample size), and outcomes (eg, time to return to sport, proportion of those who returned to sport, the self-reported questionnaire the Olerud-Molander Ankle Score). Results: A total of 10 studies and 312 patients with ankle syndesmotic injuries were included in this systematic review. The rate of return to preinjury or any injury level of sport after ankle syndesmotic injuries was 93.8% ± 1.2% and 97.6% ± 1.5%, respectively, for the corresponding 7 and 3 studies that reported this characteristic. The mean time to return to sport was 46.4 days (range, 15.4-70 days), with 55.2 ± 15.8 and 41.7 ± 9.8 days for operative and nonoperative management, respectively. Conclusion: This systematic review found a high rate of return to any as well as preinjury level of sport after ankle syndesmotic injury in both operative and nonoperative treatment groups. However, further high-level studies are required to compare operative and nonoperative treatment groups associated with return to sport after ankle syndesmotic injury.

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Evaluating measures of quality of life in adult scoliosis: a protocol for a systematic review and narrative synthesis

Systematic Reviews ◽

10.1186/s13643-021-01811-5 ◽

2021 ◽

Vol 10 (1) ◽

Author(s):

James E. Archer ◽

Charles Baird ◽

Adrian Gardner ◽

Alison B. Rushton ◽

Nicola R. Heneghan

Keyword(s):

Quality Of Life ◽

Systematic Review ◽

Outcome Measures ◽

Study Design ◽

Systematic Reviews ◽

Primary Outcome ◽

Adult Scoliosis ◽

Measurement Properties ◽

Narrative Synthesis

Abstract Background Adult scoliosis represents a distinct subgroup of scoliosis patients for whom the diagnosis can have a large impact on their health-related quality of life (HR-QOL). Therefore, HR-QOL patient-reported outcome measures (PROMs) are essential to assess disease progression and the impact of interventions. The objective of this systematic review is to evaluate the measurement properties of HR-QOL PROMs in adult scoliosis patients. Methods We will conduct a literature search, from their inception onwards, of multiple electronic databases including AMED, CINAHL, EMBASE, Medline, PsychINFO and PubMed. The searches will be performed in two stages. For both stages of the search, participants will be aged 18 and over with a diagnosis of scoliosis. The primary outcome of interest in the stage one searches will be studies which use PROMs to investigate HR-QOL as defined by the Core Outcome Measures in Effectiveness Trials (COMET) taxonomy, the secondary outcome will be to assess the frequency of use of the various PROMs. In stage two, the primary outcome of interest will be studies which assess the measurement properties of the HR-QOL PROMs identified in stage one. No specific measurement property will be given priority. No planned secondary outcomes have been identified but will be reported if discovered. In stage one, the only restriction on study design will be the exclusion of systematic reviews. In Stage two the only restriction on study design will be the exclusion of full-text articles not available in the English language. Two reviewers will independently screen all citations and abstract data. Potential conflicts will be resolved through discussion. The study methodological quality (or risk of bias) will be appraised using the Consensus-based Standards for the selection of Health Measurement Instruments (COSMIN) checklist. The overall strength of the body of evidence will then be assessed using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. A narrative synthesis will be provided with information presented in the main text and tables to summarise and explain the characteristics and findings of the included studies. The narrative synthesis will explore the evidence for currently used PROMs in adult scoliosis patients and any areas that require further study. Discussion The review will help clinicians and researchers identify a HR-QOL PROM for use in patients with adult scoliosis. Findings from the review will be published and disseminated through a peer-reviewed journal and conference presentations. Systematic review registration This systematic review has been registered with the International Prospective Register of Systematic Reviews (PROSPERO), reference number: CRD42020219437

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Case-crossover study design in pharmacoepidemiology: systematic review and recommendations

Pharmacoepidemiology and Drug Safety ◽

10.1002/pds.3508 ◽

2013 ◽

Vol 22 (11) ◽

pp. 1146-1153 ◽

Cited By ~ 22

Author(s):

Giulia P. Consiglio ◽

Andrea M. Burden ◽

Malcolm Maclure ◽

Lisa McCarthy ◽

Suzanne M. Cadarette

Keyword(s):

Systematic Review ◽

Crossover Study ◽

Study Design ◽

Case Crossover

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To explore the barriers to and facilitators of adolescents in Low-Middle-Income- Countries (LMICs) seeking mental health care: Protocol for a Mixed-Methods Systematic Review

10.21203/rs.3.rs-215110/v1 ◽

2021 ◽

Author(s):

Sudha Subhadra Kallakuri ◽

Pallab K Maulik ◽

Prachi Kaistha ◽

Maree Hackett

Keyword(s):

Mental Health ◽

Systematic Review ◽

Mixed Methods ◽

Study Design ◽

Critical Appraisal ◽

Mental Illnesses ◽

World Health ◽

Middle Income ◽

Middle Income Countries ◽

Low Middle Income Countries

Abstract Background: Adolescence is a very important transitional phase for an individual as they move from childhood to adulthood. In 2007, the World Health Organization reported that 16% of the global burden of disease and injuries occur among adolescents i.e. those aged between 10 and 19 years, most of them starting by the age of 14 years and usually become serious; if left unrecognised or unattended at that point in time. Several risk factors are associated with increases in the mental health disorders. It is pertinent to promote interventions which teach life skills like regulating one’s emotions, building resilience, and dealing with difficult situations with confidence and strength. This mixed-methods systematic review aims to synthesise best available evidence on the barriers and facilitators to help seeking for mental illnesses among adolescents in Low-Middle-Income Countries Methods and Analyses: The systematic review will be conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Systematic searches will be carried out in electronic databases like PubMed,EMBASE, PsychINFO, Sociofile, CINAHL to identify studies relevant to the review question. At the first stage, titles and abstracts of articles retrieved through the searches will be examined against the eligibility criteria. The second stage will involve independent full-text screening of included articles by two reviewers. All qualitative, quantitative, and mixed method research studies which explicitly answer the research questions will be considered in this review. Methodological appraisal (Risk of Bias) will be conducted using the Joanna Briggs Institute's standardized critical appraisal tools or other standardized critical appraisal tools contingent on the study design by two reviewers. Data will be extracted on the aims/purpose, study design, geographical location, study population, study duration, interventions (if applicable) outcomes, and results of included studies. Data analyses will be conducted using the convergent approach to analysis of mixed methods research using JBI guidance. Discussion: The research will help to identify gaps in knowledge and generate evidence for health departments to look more specifically at the mental health of adolescents and challenges of addressing them. Systematic Review Registration: PROSPERO: CRD42020214349

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