Extracorporeal CO 2 removal and renal replacement therapy in acute severe respiratory failure in COVID‐19 pneumonia: Case report

Introduction: Sodium fluoroacetate, known as compound 1080, was discovered in Germany during the Second World War. It is usually used as a rodenticide, it is an odorless and tasteless substance, with a lethal dose in humans of 2 mg / kg that is why it was withdrawn from the market in some countries, including Colombia; however, it is obtained illegally. This substance has biochemical and physiological effects at the cellular level that alter the transport of citrate at the mitochondrial level, generating accumulation of lactic acid and alteration of the glucose use. The clinical manifestations are nonspecific since there is no any cardinal symptom. Therefore, its diagnosis is made due to high clinical suspicion associated with establishment of exposure to the compound in view of the difficulty to obtain paraclinical confirmation in a timely manner. Methods: We present a case report of intentional ingestion of sodium fluoroacetate in an adolescent that is associated with an infection added to the bloodstream by methicillin- sensitive Staphylococcus aureus (MSSA). The patient developed multiple complications that lead to support in the Intensive Care Unit (ICU) with a satisfactory outcome. In view of the lack of a specific antidote, she was treated with ethanol in order to increase the level of acetate; thus, offering an alternative substrate to the Krebs cycle. It is suggested that the ethanol offers benefits in the acute treatment of these patients. Results: The patient with sodium fluoroacetate poisoning and kidney failure received renal replacement therapy with a favorable evolution and survival at discharge from the intensive care unit of a third-level hospital in the city of Pereira, Risaralda, Colombia. Conclusions: Sodium fluoroacetate poisoning is relatively rare and can cause acute kidney injury and multi-organ failure with a high rate of complications and death. A case of self-inflicted poisoning that received a timely manner continuous renal replacement therapy with a favorable outcome in terms of ICU survival was presented.

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Physiotherapy Management of Young Male with Severe Symptoms of COVID- 19 Infection: A Case Study

International Journal of Research and Review ◽

10.52403/ijrr.20210450 ◽

2021 ◽

Vol 8 (4) ◽

pp. 422-428

Author(s):

Gauri Wakde ◽

Prajakta Patil ◽

Sumit Jadhav

Keyword(s):

Case Report ◽

Respiratory Failure ◽

Multidisciplinary Team ◽

Medical Management ◽

Young Male ◽

Age Group ◽

Severe Respiratory Failure ◽

Respiratory Illnesses ◽

Remarkable Recovery

COVID-19 is worldwide pandemic affecting every age group with symptoms ranging from asymptomatic or mild to severe respiratory failure. COVID being highly transmittable and pathogenic disease has caused huge burden worldwide for more than a year. Severe symptoms of COVID19 require immediate hospitalisation and prompt medical management. This case study illustrates the recovery of a young male patient with severe symptoms of COVID-19 with complications of ARDS and Polyneuropathy. Physiotherapy has been an integral part of multidisciplinary team in management of COVID 19 patients especially with severe respiratory illnesses. The case report mainly highlights the Physiotherapy management for the patient in camaraderie to the Medical management which resulted in remarkable recovery of the patient. Keywords: COVID, Coronavirus, case report, case study, severe symptoms, physiotherapy, ARDS, polyneuropathy.

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Iris rubeosis, severe respiratory failure and retinopathy of prematurity – case report

Ginekologia Polska ◽

10.17772/gp/1695 ◽

2014 ◽

Vol 85 (1) ◽

Cited By ~ 1

Author(s):

Monika Modrzejewska ◽

Urszula Kulik ◽

Wojciech Lubiński

Keyword(s):

Case Report ◽

Respiratory Failure ◽

Retinopathy Of Prematurity ◽

Severe Respiratory Failure

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Successful Use of Extracorporeal Life Support and Continuous Renal Replacement Therapy in the Treatment of Cardiogenic Shock Induced by Tumor Lysis Syndrome in a Pediatric Patient With Lymphoma: A Case Report

Frontiers in Medicine ◽

10.3389/fmed.2021.762788 ◽

2022 ◽

Vol 8 ◽

Author(s):

Zhulin Wang ◽

Fang Zhang ◽

Long Xiang ◽

Yinyu Yang ◽

Wei Wang ◽

...

Keyword(s):

Case Report ◽

Renal Replacement Therapy ◽

Cardiopulmonary Resuscitation ◽

Cardiogenic Shock ◽

Continuous Renal Replacement Therapy ◽

Replacement Therapy ◽

Tumor Lysis Syndrome ◽

Electrolyte Imbalance ◽

Tumor Lysis ◽

Critical Ultrasound

The use of extracorporeal membrane oxygenation (ECMO) in the treatment of cardiopulmonary failure in children with malignant tumors is controversial. There are few reports on the use of ECMO in the treatment of children with tumor lysis syndrome. This article reports a case of a 9-year-old girl who presented with hyperkalemia and cardiogenic shock. The discovery of an abdominal mass with critical ultrasound provided key evidence for the initial diagnosis of tumor lysis syndrome. Cardiopulmonary resuscitation was performed for 1 h. Veno-arterial ECMO was installed at the bedside to provide cardiopulmonary support for the patient and was combined with continuous renal replacement therapy (CRRT) to improve her internal environment. The patient was ultimately diagnosed with mature B-cell lymphoma with tumor lysis syndrome. A severe electrolyte disorder led to cardiogenic shock. After the electrolyte imbalance was corrected, the patient's heart function gradually improved, ECMO was successfully weaned, and chemotherapy was continued with the support of CRRT. One month after ECMO weaning, the organ function of the patient had recovered and there were no serious complications. In this case report, we paid attention to the rapid diagnosis of the etiology behind a patient's shock with critical ultrasound as well as the initiation and management of extracorporeal cardiopulmonary resuscitation (ECPR), which provided us with valuable experience using VA-ECMO on critically ill children with tumors. It is also important evidence for the use of ECMO in the treatment of children with cardiopulmonary arrest secondary to malignancy.

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