scholarly journals Mechanistic study on the species differences in excretion pathway of HR011303 in human and rats

2021 ◽  
pp. DMD-AR-2021-000582
Zitao Guo ◽  
Mengling Liu ◽  
Jian Meng ◽  
Yaru Xue ◽  
Qi Huang ◽  
Edward D. DeLamater ◽  
Walter R. Courtenay ◽  
Cecil Whitaker

Comparative scanning electron microscopy studies of fish scales of different orders, families, genera and species within genera have demonstrated differences which warrant elaboration. These differences in detail appear to be sufficient to act as “fingerprints”, at least, for family differences. To date, the lateral line scales have been primarily studied. These demonstrate differences in the lateral line canals; the pattern of ridging with or without secondary protuberances along the edges; the pattern of spines or their absence on the anterior border of the scales; the presence or absence of single or multiple holes on the ventral and dorsal sides of the lateral line canal covers. The distances between the ridges in the pattern appear likewise to be important.A statement of fish scale structure and a comparison of family and species differences will be presented.The authors wish to thank Dr. Donald Marzalek and Mr. Wallace Charm of the Marine and Atmospheric Laboratory of the University of Miami and Dr. Sheldon Moll and Dr. Richard Turnage of AMR for their exhaustive help in these preliminary studies.

2001 ◽  
Vol 120 (5) ◽  
pp. A145-A145
C CHO ◽  
Y YE ◽  
E LIU ◽  
V SHIN ◽  

2019 ◽  
Vol 133 (4) ◽  
pp. 474-487 ◽  
Eloísa M. Guerreiro Martins ◽  
Antonio C. de A. Moura ◽  
Christa Finkenwirth ◽  
Michael Griesser ◽  
Judith M. Burkart

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
L Wang ◽  
L Shan ◽  
G Cui ◽  
Y Chen ◽  
J li ◽  

2018 ◽  
Sandepan Maity ◽  
Robert Flowers

Despite the broad utility and application of SmI<sub>2</sub>in synthesis, the reagent is used in stoichiometric amounts and has a high molecular weight, resulting in a large amount of material being used for reactions requiring one or more equivalents of electrons. We report mechanistic studies on catalytic reactions of Sm(II) employing a terminal magnesium reductant and trimethyl silyl chloride in concert with a non-coordinating proton donor source. Reactions using this approach permitted reductions with as little as 1 mol% Sm. The mechanistic approach enabled catalysis employing HMPA as a ligand, facilitating the development of catalytic Sm(II) 5-<i>exo</i>-<i>trig </i>ketyl olefin cyclization reactions.

2019 ◽  
Chem Int

Activated carbon was prepared from molasses, which are natural precursors of vegetable origin resulting from the sugar industry. A simple elaboration process, based on chemical activation with phosphoric acid, was proposed. The final product, prepared by activation of molasses/phosphoric acid mixture in air at 500°C, presented high surface area (more than 1400 m2/g) and important maximum adsorption capacity for methylene blue (625 mg/g) and iodine (1660 mg/g). The activated carbon (MP2(500)) showed a good potential for the adsorption of Cr(VI), Cu(II) and Pb(II) from aqueous solutions. The affinity for the three ions was observed in the following order Cu2+ Cr6+ Pb2+. The process is governed by monolayer adsorption following the Langmuir model, with a correlation coefficient close to unity.

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