scholarly journals Vesicular Stomatitis Virus Chimeras Expressing the Oropouche Virus Glycoproteins Elicit Protective Immune Responses in Mice

mBio ◽  
2021 ◽  
Author(s):  
Sarah Hulsey Stubbs ◽  
Marjorie Cornejo Pontelli ◽  
Nischay Mishra ◽  
Changhong Zhou ◽  
Juliano de Paula Souza ◽  
...  

Oropouche virus (OROV), an orthobunyavirus found in Central and South America, is an emerging public health challenge that causes debilitating febrile illness. OROV is transmitted by arthropods, and increasing mobilization has the potential to significantly increase the spread of OROV globally.

2020 ◽  
Vol 99 (6) ◽  
pp. 15-31
Author(s):  
A.A. Korenkova ◽  
◽  
E.M. Mayorova ◽  
V.V. Bahmetjev ◽  
M.V. Tretyak ◽  
...  

The new coronavirus infection has posed a major public health challenge around the world, but new data on the disease raises more questions than answers. The lack of optimal therapy is a significant problem. The article examines the molecular mechanisms of SARS-CoV-2 infection and the pathogenesis of COVID-19, special attention is paid to features of pathological processes and immune responses in children. COVID-19 leads to a wide diversity of negative outcomes, many of which can persist for at least months. Many of the consequences have yet to be identified. SARS-CoV-2 may provoke autoimmune reactions. Reinfection, herd immunity, vaccines and other prevention measures are also discussed in this review.


PLoS ONE ◽  
2018 ◽  
Vol 13 (10) ◽  
pp. e0204811 ◽  
Author(s):  
Naja Hulvej Rod ◽  
Agnete Skovlund Dissing ◽  
Alice Clark ◽  
Thomas Alexander Gerds ◽  
Rikke Lund

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