scholarly journals Materials Based on Chitosan and Polylactide: From Biodegradable Plastics to Tissue Engineering Constructions

2021 ◽  
Vol 63 (2) ◽  
pp. 219-226
Author(s):  
T. S. Demina ◽  
T. A. Akopova ◽  
A. N. Zelenetsky

Abstract The transition to green chemistry and biodegradable polymers is a logical stage in the development of modern chemical science and technology. In the framework of this review, the advantages, disadvantages, and potential of biodegradable polymers of synthetic and natural origin are compared using the example of polylactide and chitosan as traditional representatives of these classes of polymers, and the possibilities of their combination via obtaining composite materials or copolymers are assessed. The mechanochemical approach to the synthesis of graft copolymers of chitosan with oligolactides/polylactides is considered in more detail.

2016 ◽  
Vol 4 (22) ◽  
pp. 3998-4008 ◽  
Author(s):  
Wenqiang Du ◽  
Jianfeng Chen ◽  
Huan Li ◽  
Gang Zhao ◽  
Guangli Liu ◽  
...  

We introduce the substrates of composite materials for sphincter tissue engineering and demonstrate the mechanisms of how dimensions, curvature and parallelism of constraints affect cellular organization.


Author(s):  
Raffaele Conte ◽  
Francesco Riccitiello ◽  
Adriana De Luise ◽  
Orsolina Petillo ◽  
Carlo Rengo ◽  
...  

1995 ◽  
Vol 394 ◽  
Author(s):  
Jeffrey S. Hrkach ◽  
Jean Ou ◽  
Noah Lotan ◽  
Robert Langer

AbstractOne of the challenges in the field of tissue engineering is the development of optimal materials for use as scaffolds to support cell growth and tissue development. For this purpose, we are developing synthetic, biodegradable polymers with functional sites that provide the opportunity to covalently attach biologically active molecules to the polymers, so they can predictably interact with cells in a favorable manner to enhance cell attachment and growth. The preparation of poly(L-lactic acid-co-aspartic acid) comb-like graft copolymers from poly(L-lactic acid-co-β-benzyl-L-aspartate), and the casting of polymer films by solvent evaporation were carried out.


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